alkynylation  Ar-C(O) cleavage  ligand  palladium  late-stage diversification  

ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  

A series of late-transition metal complexes supported with chlorinated bis(arylimino)pyridine ligands [2  Ar = 2  Ar = 2  Ar = 2  Ar = 4-Cl-2  Ar = 4-Br-2  6-(ArN=CCl)(2)C5H3N]MtCl(2) (Ar = 2  6-(Pr2C6H3)-Pr-i  6-Et2C6H3  6-Me2C6H3  6-Me2C6H2  6-Me2C6H2  4  Mt = Fe (1b)  Mt = Co (1c)  Mt = Fe (1d)  Mt = Fe (1e)  Mt = Fe (1f)  6-Me3C6H2  Co (2b)  Ni (3c)  Co (2d)  Co (2e)  Co (2f)) were synthesized. At the presence of methylaluminoxane (MAO)  Mt = Fe (1a)  Fe(II)- and Co(II)- based complexes were highly active towards ethylene polymerization  Co (2a)  affording polymers with bimodal and unimodal molar. mass distributions  Ni (3a)  respectively  while the Ni(II)-based complexes gave no polymer products. Moreover  the obtained polyethylenes were predominately saturated and vinyl-terminated for Fe(II)- and Co(II)-based complexes  respectively. Changing the ligand environment  polymerization parameters also posed a great influence on the catalytic activities and the properties of the resulting polymers. (C) 2014 Elsevier Ltd. All rights reserved.  

N-HETEROCYCLIC CARBENE  UNSUPPORTED SILVER-GERMANIUM  COPPER(I) ALKYL COMPLEXES  PI-STACKING INTERACTIONS  GROUP-16 ELEMENTS  REACTIVITY  CHEMISTRY  LIGAND  AR=2,6-IPR(2)C(6)H(3)  AU  

MN-II  LIGAND  3-COORDINATE  AR=2,6-IPR(2)C(6)H(3)  DERIVATIVES  MAGNETISM  CARBENE  CORE