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CORC

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Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64
作者:  Fu, Weitao;  Zhang, Minkui;  Liao, Jianing;  Tang, Qing;  Lei, Yixuan
收藏  |  浏览/下载：49/0  |  提交时间：2022/03/21
TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia 期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2021, 卷号: 378, 期号: 1, 页码: 20-30
作者:  Wang, Yu;  He, Yang;  Yang, Feipu;  Abame, Melkamu Alemu;  Wu, Chunhui
收藏  |  浏览/下载：37/0  |  提交时间：2021/11/04
Design, synthesis and biological evaluation of novel thiohydantoin derivatives as potent androgen receptor antagonists for the treatment of prostate cancer 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 31, 页码: 13
作者:  Wang, Ao;  Wang, Yawan;  Meng, Xin;  Yang, Yushe
收藏  |  浏览/下载：14/0  |  提交时间：2021/05/24
Efficacy of Pyrotinib in HER2-Overexpressing Salivary Duct Carcinoma With Lung Metastasis: A Case Report 期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:  Yang, Zi-yan;  Huang, Jia-huan;  Chen, Bo;  Xu, Chun-wei;  Lei, Lei
收藏  |  浏览/下载：26/0  |  提交时间：2020/11/30
Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays 期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 16, 期号: 6, 页码: 416-427
作者:  Hou, Tingjun;  Li, Dan;  Chang, Shan;  Xu, Lei;  Sun, Huiyong
收藏  |  浏览/下载：260/0  |  提交时间：2019/06/24
A comparison of endocrine disruption potential of nonylphenol ethoxylate, vanillin ethoxylate, 4-n-nonylphenol and vanillin in vitro 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 175, 页码: 208-214
作者:  Ji, Xiaoya;  Li, Na;  Yuan, Shengwu;  Zhou, Xiaohong;  Ding, Fengmei
收藏  |  浏览/下载：14/0  |  提交时间：2020/10/23
Identification of serotonin 2a receptor as a novel hcv entry factor by a chemical biology strategy 期刊论文
Protein & cell, 2019, 卷号: 10, 期号: 3, 页码: 178-195
作者:  Cao, Lin;  Chen, Jizheng;  Wang, Yaxin;  Yang, Yuting;  Qing, Jie
收藏  |  浏览/下载：484/0  |  提交时间：2019/05/08
Communication between the Ligand-Binding Pocket and the Activation Function-2 Domain of Androgen Receptor Revealed by Molecular Dynamics Simulations 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2019, 卷号: 59, 期号: 2, 页码: 842-857
作者:  Hou, Tingjun;  Li, Youyong;  Yu, Huidong;  Li, Dan;  Liu, Hui
收藏  |  浏览/下载：67/0  |  提交时间：2019/06/24
Targeting Purinergic Receptor P2Y2 Prevents the Growth of Pancreatic Ductal Adenocarcinoma by Inhibiting Cancer Cell Glycolysis 期刊论文
CLINICAL CANCER RESEARCH, 2019, 卷号: 25, 页码: 1318-1330
作者:  Hu, Li-Peng;  Zhang, Xiao-Xin;  Jiang, Shu-Heng;  Tao, Ling-Ye;  Li, Qing
收藏  |  浏览/下载：31/0  |  提交时间：2019/12/02
adenosine triphosphate  ar c118925xx  gemcitabine  glucose transporter 1  hypoxia inducible factor 1alpha  Myc protein  platelet derived growth factor beta receptor  platelet derived growth factor receptor  protein kinase Yes  purinergic P2Y receptor antagonist  purinergic P2Y2 receptor  unclassified drug  Yes1 protein, Akt signaling  animal experiment  animal model  animal tissue  Article  cancer inhibition  cancer prognosis  cancer staging  controlled study  drug potentiation  glycolysis  human  human cell  human tissue  inflammation  lymph node metastasis  male  mouse  mouse model  nonhuman  overall survival  pancreas adenocarcinoma  pancreatic ductal carcinoma cell line  Pi3K/Akt signaling  priority journal  RNA sequence  tumor classification  tumor differentiation  tumor microenvironment  tumor volume  tumor xenograft  
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay 期刊论文
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
作者:  Wang, Anhui;  Zhang, Pengyu;  Wang, Jixia;  Zhao, Ying;  Zhang, Xiuli
收藏  |  浏览/下载：54/0  |  提交时间：2019/06/20

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