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上海药物研究所 [8]
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期刊论文 [26]
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Simulating androgen receptor selection in designer yeast
期刊论文
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2022, 卷号: 7
作者:
Zhang, Haoran
;
Zhang, Lu
;
Xu, Yipeng
;
Chen, Shaoyong
;
Ma, Zhenyi
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/12/23
Androgen receptor mutations
Androgen receptor antagonists
Prostate cancer
Saccharomyces cerevisiae
Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64
作者:
Fu, Weitao
;
Zhang, Minkui
;
Liao, Jianing
;
Tang, Qing
;
Lei, Yixuan
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/03/21
Design, synthesis and biological evaluation of novel thiohydantoin derivatives as potent androgen receptor antagonists for the treatment of prostate cancer
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 31, 页码: 13
作者:
Wang, Ao
;
Wang, Yawan
;
Meng, Xin
;
Yang, Yushe
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/05/24
Androgen receptor
Novel thiohydantoin derivatives
Androgen receptor antagonists
Prostate cancer
Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays
期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 16, 期号: 6, 页码: 416-427
作者:
Hou, Tingjun
;
Li, Dan
;
Chang, Shan
;
Xu, Lei
;
Sun, Huiyong
收藏
  |  
浏览/下载:260/0
  |  
提交时间:2019/06/24
Androgen receptor
AR ligand
Virtual screening
AR agonist
AR antagonist
A comparison of endocrine disruption potential of nonylphenol ethoxylate, vanillin ethoxylate, 4-n-nonylphenol and vanillin in vitro
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 175, 页码: 208-214
作者:
Ji, Xiaoya
;
Li, Na
;
Yuan, Shengwu
;
Zhou, Xiaohong
;
Ding, Fengmei
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/10/23
Nonylphenol ethoxylate
Vanillin ethoxylate
4-n-nonylphenol
Vanillin
Nuclear receptors
Two-hybrid yeast
Design, synthesis, and biological evaluation of 2-(5-methyl-1H-pyrazol-1-yl) acetamide derivatives as androgen receptor antagonists
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2019, 卷号: 28, 期号: 3, 页码: 380-386
作者:
Dong, Junze
;
Zhang, Jingya
;
Li, Zilu
;
Asnake, Solomon
;
Zhang, Daoguang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/11
Androgen receptor
Prostate cancer
Antagonists
Pyrazole derivatives
Synthesis of androgen receptor antagonists containing a pentafluorosulfanyl (SF5) moiety
期刊论文
ARCHIV DER PHARMAZIE, 2018, 卷号: 351, 期号: 11
作者:
Jin, Jiyu
;
Zhou, Yan
;
Yang, Dehua
;
Zhang, Qiumeng
;
Wang, Ming-Wei
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2019/01/08
androgen receptor
antagonist
enzalutamide
pentafluorosulfanyl
CMKLR1 deficiency attenuates androgen-induced lipid accumulation in mice.
期刊论文
Cellular Physiology and Biochemistry, 2018
作者:
Zhao Huashan
;
Wu Linlin
;
Huang Chen
;
Xiang Liang
;
Wang Baobei
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2019/01/31
Combined Ligand/Structure-Based Virtual Screening and Molecular Dynamics Simulations of Steroidal Androgen Receptor Antagonists
期刊论文
BIOMED RESEARCH INTERNATIONAL, 2017
作者:
Wang, YW
;
Han, R
;
Zhang, HM
;
Liu, HL
;
Li, JZ
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2017/05/09
Synthesis and biological evaluation of 3-(4-fluorophenyl)-1H-pyrazole derivatives as androgen receptor antagonists
期刊论文
Anti-Cancer Drugs, 2016, 卷号: 27, 期号: 4, 页码: 278-285
作者:
Guangzhu.Guo
;
Jianzhen.Liu
;
Guanjie.Wang
;
Daoguang.Zh
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
antagonist
pyrazole derivatives
androgen receptor
prostate cancer
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