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复旦大学上海医学院 [11]
中南大学 [4]
上海药物研究所 [3]
武汉大学 [3]
中国医学科学院 北京... [3]
北京大学 [2]
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期刊论文 [38]
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Calpain-2 Enhances Non-Small Cell Lung Cancer Progression and Chemoresistance to Paclitaxel via EGFR-pAKT Pathway
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2019, 卷号: 15, 期号: 1
作者:
Xu, Fengkai
;
Gu, Jie
;
Lu, Chunlai
;
Mao, Wei
;
Wang, Lin
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/05
Calpain-2
non-small cell lung cancer
paclitaxel
chemoresistance
prognosis
Descending-SHIP2-mediated radiosensitivity enhancement through PI3K/Akt signaling pathway in laryngeal squamous cell carcinoma
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 118
作者:
Tang, Tian
;
Xiao, Zhu-Ya
;
Shan, Guang
;
Lei, Hong-Bo
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Descending-SHIP2-mediated radiosensitivity enhancement
Laryngeal squamous cell carcinoma
SHIP2
PI3K/Akt
pAKT
Radiosensitivity
Yanghe Huayan decoction inhibits the capability of trans-endothelium and angiogenesis of HER2+breast cancer via pAkt signaling
期刊论文
BIOSCIENCE REPORTS, 2019, 卷号: 39, 期号: 2
作者:
Liu, Xiao-Fei
;
Li, Jing-Wei
;
Chen, Hong-Zhi
;
Sun, Zi-Yuan
;
Shi, Guang-Xi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
Phosphorylation of LIFR promotes prostate cancer progression by activating the AKT pathway
期刊论文
CANCER LETTERS, 2019, 卷号: 451, 页码: 110-121
作者:
Shao, Jialiang
;
Zhu, Wencheng
;
Ding, Yufeng
;
Zhu, Hongwen
;
Jing, Xiaoqian
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
LIFR
Phosphorylation
Prostate cancer
AKT
Egress of murine regulatory T cells from the thymus requires TIPE2.
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018
作者:
Fan, Tingting
;
Huang, Xiaowen
;
Liu, Cuilian
;
Liu, Ruiling
;
Wang, Ting
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/31
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
PI3K-AKT Pathway Protects Cardiomyocytes Against Hypoxia-Induced Apoptosis by MitoKATP-Mediated Mitochondrial Translocation of pAKT
期刊论文
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, 卷号: 49, 期号: 2
作者:
Song, Hua-Pei
;
Chu, Zhi-Gang
;
Zhang, Dong-Xia
;
Dang, Yong-Ming
;
Zhang, Qiong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Pi3k-AKT
Cardiomyocytes
Hypoxic
Mitochondrial
MitoKATP
Apoptosis
LncRNA PIK3CD-AS1在肾癌细胞中的功能和机制初步研究
学位论文
: 江苏大学, 2018
作者:
钱洲楠[1]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/24
肾癌
长链非编码RNA
PIK3CD-AS1
过表达载体
增殖
凋亡
基因芯片
pAKT
肿瘤胞外酸性微环境对肾癌769-P细胞株体外侵袭能力及其LncRNA表达谱的影响
学位论文
: 江苏大学, 2018
作者:
殷喜丰[1]
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/24
肿瘤胞外酸性微环境
肾癌
细胞侵袭
Snail
pAKT/AKT及ERK信号通路
长链非编码RNA
CRISPR/Cpf1
The oncoprotein HBXIP promotes human breast cancer growth through down-regulating p53 via miR-18b/MDM2 and pAKT/MDM2 pathways
期刊论文
2018, 卷号: 39, 期号: 11, 页码: 1787-1796
作者:
Li, Hang
;
Wang, Zhen
;
Jiang, Mian
;
Fang, Run-ping
;
Shi, Hui
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/01/03
HBXIP
p53
MDM2
miR-18b
pAKT
human breast cancer
cell proliferation
MCF-7 cells
cancer xenograft nude mice
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