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Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A(2A) Receptor Targeting the Sodium Ion Pocket 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 6, 页码: 991-1002
作者:  Lu, Yan;  Liu, Hongyue;  Yang, Dehua;  Zhong, Li;  Xin, Ye
收藏  |  浏览/下载:25/0  |  提交时间:2021/08/17
Disulfide-Containing Detergents (DCDs) for the Structural Biology of Membrane Proteins 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2019, 页码: 7
作者:  Xue, Dongxiang;  Xu, Tiandan;  Wang, Huixia;  Wu, Meng;  Yuan, Ya
收藏  |  浏览/下载:65/0  |  提交时间:2020/07/01
Identification of serotonin 2a receptor as a novel hcv entry factor by a chemical biology strategy 期刊论文
Protein & cell, 2019, 卷号: 10, 期号: 3, 页码: 178-195
作者:  Cao, Lin;  Chen, Jizheng;  Wang, Yaxin;  Yang, Yuting;  Qing, Jie
收藏  |  浏览/下载:484/0  |  提交时间:2019/05/08
Broad targeting of triptolide to resistance and sensitization for cancer therapy 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:  Hou, Zhen-yan;  Tong, Xiao-pei;  Peng, Yong-bo;  Zhang, Bi-Kui*;  Yan, Miao*
收藏  |  浏览/下载:48/0  |  提交时间:2019/12/03
ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  
精神分裂症5-HT2AR基因多态性与帕利哌酮临床疗效的关联性分析 学位论文
2017
作者:  熊子珺
收藏  |  浏览/下载:1/0  |  提交时间:2019/12/05
Dahe Qin: time is limited to curb global warming 期刊论文
NATIONAL SCIENCE REVIEW, 2016, 卷号: 3, 期号: 1, 页码: 144-147
作者:  Wang, Ling;  Zhou, Zhonghe
收藏  |  浏览/下载:13/0  |  提交时间:2016/12/09
Cholesterol-beta(1)AR interaction versus cholesterol-beta(2)AR interaction 期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2014, 卷号: 82, 期号: 5, 页码: 760-770
作者:  Cang, Xiaohui;  Yang, Linlin;  Yang, Jing;  Luo, Cheng;  Zheng, Mingyue
收藏  |  浏览/下载:44/0  |  提交时间:2019/01/08
Efficient and Heteroselective Heteroscorpionate Rare-Earth-Metal Zwitterionic Initiators for ROP of rac-Lactide: Role of sigma-Ligand 期刊论文
MACROMOLECULES, 2014, 卷号: 47, 期号: 7, 页码: 2233-2241
作者:  Mou, Zehuai;  Liu, Bo;  Liu, Xinli;  Xie, Hongyan;  Rong, Weifeng
收藏  |  浏览/下载:17/0  |  提交时间:2019/04/09
GPCR A(2A)AR Agonist Binding and Induced Conformation Changes of Functional Switches 期刊论文
chinese journal of chemical physics, 2014, 卷号: 27, 期号: 1, 页码: 29-38
作者:  Pang, Xue-qin;  Liu, Jian-yong
收藏  |  浏览/下载:16/0  |  提交时间:2015/11/17
Highly active half-sandwich chromium(III) catalysts bearing bis(imino)pyrrole ligands for ethylene (co) polymerization 期刊论文
RSC ADVANCES, 2014, 卷号: 4, 期号: 37, 页码: 19433-19439
作者:  Liu, Jing-Yu;  Tao, Ping;  Wang, Yong-Xia;  Li, Yue-Sheng
收藏  |  浏览/下载:14/0  |  提交时间:2019/04/09


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