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长春应用化学研究所 [11]
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Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A(2A) Receptor Targeting the Sodium Ion Pocket
期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 6, 页码: 991-1002
作者:
Lu, Yan
;
Liu, Hongyue
;
Yang, Dehua
;
Zhong, Li
;
Xin, Ye
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
Disulfide-Containing Detergents (DCDs) for the Structural Biology of Membrane Proteins
期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2019, 页码: 7
作者:
Xue, Dongxiang
;
Xu, Tiandan
;
Wang, Huixia
;
Wu, Meng
;
Yuan, Ya
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2020/07/01
detergents
disulfides
membrane proteins
micelle size
NMR spectroscopy
Identification of serotonin 2a receptor as a novel hcv entry factor by a chemical biology strategy
期刊论文
Protein & cell, 2019, 卷号: 10, 期号: 3, 页码: 178-195
作者:
Cao, Lin
;
Chen, Jizheng
;
Wang, Yaxin
;
Yang, Yuting
;
Qing, Jie
收藏
  |  
浏览/下载:484/0
  |  
提交时间:2019/05/08
Hcv
Serotonin 2a receptor
Entry
Antiviral drug
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
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  |  
浏览/下载:48/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
精神分裂症5-HT2AR基因多态性与帕利哌酮临床疗效的关联性分析
学位论文
2017
作者:
熊子珺
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/05
精神分裂症
5-羟色胺2A受体
帕利哌酮
多态性
Dahe Qin: time is limited to curb global warming
期刊论文
NATIONAL SCIENCE REVIEW, 2016, 卷号: 3, 期号: 1, 页码: 144-147
作者:
Wang, Ling
;
Zhou, Zhonghe
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2016/12/09
Cholesterol-beta(1)AR interaction versus cholesterol-beta(2)AR interaction
期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2014, 卷号: 82, 期号: 5, 页码: 760-770
作者:
Cang, Xiaohui
;
Yang, Linlin
;
Yang, Jing
;
Luo, Cheng
;
Zheng, Mingyue
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
cholesterol-binding site
beta-adrenergic receptor
molecular dynamics simulation
G protein-coupled receptor
Efficient and Heteroselective Heteroscorpionate Rare-Earth-Metal Zwitterionic Initiators for ROP of rac-Lactide: Role of sigma-Ligand
期刊论文
MACROMOLECULES, 2014, 卷号: 47, 期号: 7, 页码: 2233-2241
作者:
Mou, Zehuai
;
Liu, Bo
;
Liu, Xinli
;
Xie, Hongyan
;
Rong, Weifeng
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/04/09
GPCR A(2A)AR Agonist Binding and Induced Conformation Changes of Functional Switches
期刊论文
chinese journal of chemical physics, 2014, 卷号: 27, 期号: 1, 页码: 29-38
作者:
Pang, Xue-qin
;
Liu, Jian-yong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2015/11/17
A(2A) adenosine receptor
Molecular dynamics
Adenosine
Specific binding
Conformational dynamics
Ionic lock
Rotamer toggle switch
Secondary structure
Highly active half-sandwich chromium(III) catalysts bearing bis(imino)pyrrole ligands for ethylene (co) polymerization
期刊论文
RSC ADVANCES, 2014, 卷号: 4, 期号: 37, 页码: 19433-19439
作者:
Liu, Jing-Yu
;
Tao, Ping
;
Wang, Yong-Xia
;
Li, Yue-Sheng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/04/09
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