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武汉大学 [10]
上海药物研究所 [6]
中南大学 [6]
复旦大学上海医学院 [5]
山东大学 [3]
四川大学 [2]
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期刊论文 [26]
学位论文 [11]
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Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
99mTc-MIBI SPECT/CT功能影像在甲状旁腺功能亢进症中的应用研究及机制探讨
学位论文
2018
作者:
薛建军
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/11/26
甲状旁腺功能亢进症
99mTc-MIBI显像
P-gp
MRP1
GST-&pi
Endogenous Stimuli-Responsive Nucleus-Targeted Nanocarrier for Intracellular mRNA Imaging and Drug Delivery
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2018, 卷号: 10, 期号: 46, 页码: 39524-39531
作者:
Liu, Xiaoting
;
Wang, Lei
;
Xu, Xiaowen
;
Zhao, Haiyan
;
Jiang, Wei
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
nanocarrier
stimuli responsive
nucleus-targeted
MRP1 mRNA imaging
drug delivery
Reversal of multidrug resistance by icaritin in doxorubicin-resistant human osteosarcoma cells
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2018, 卷号: 16, 期号: 1, 页码: 20
作者:
Wang ZhenDong
;
Wang RuiZhi
;
Xia YuanZheng
;
Kong LingYi
;
Yang Lei
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/12/24
CHEMOTHERAPEUTIC-AGENTS
HERBA-EPIMEDII
CANCER-CELLS
TRANSPORTERS
EXPRESSION
FLAVONOIDS
PROTEIN-1
ABCB1
PHARMACOKINETICS
PROLIFERATION
Osteosarcoma
Icaritin
Multidrug resistance
MDR1
MRP1
Reversal of multidrug resistance by Marsdenia tenacissima and its main active ingredients polyoxypregnanes
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2017, 卷号: 203, 页码: 110-119
作者:
To, Kenneth K. W.
;
Wu, Xu
;
Yin, Chun
;
Chai, Stella
;
Yao, Sheng
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/01/08
ABCG2
Multidrug resistance
Marsdenia tenacissima
MRP1
P-glycoprotein
Polyoxypregnane compounds
Combination of metformin with chemotherapeutic drugs via different molecular mechanisms
期刊论文
Cancer Treatment Reviews, 2017, 卷号: 54, 页码: 24-33
作者:
Peng, Mei*
;
Darko, Kwame Oteng
;
Tao, Ting
;
Huang, Yanjun
;
Su, Qiongli
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
AIs
aromatase inhibitors
AMPK
Adenosine Monophosphate-Activated Protein Kinase
AR
androgen
ATM
Ataxia Telangiectasia Mutated
ATP
Adenosine Triphosphate
BCSS
breast cancer specific survival
CK-MB
Creatine Kinase-MB
CREB1
cAMP Response Element-Binding Protein 1
CSC
cancer stem cell
DFS
disease-free survival
DHFU
dihydrofluorouracil
DPD
dihydropyrimidine dehydrogenase
EpCAM
Epithelial Cell Adhesion Molecule
ER
estrogen
ERCC1
excision repair cross-complementary 1
ERK
extracellular signal-regulated kinases
EZH2
enhancer of zeste homolog 2
FdUMP
fluorodeoxyuridine monophosphate
FdUTP
fluorodeoxyuridine triphosphate
FHC
ferritin heavy chain
FUTP
fluorouridine triphosphate
HbA1C
hemoglobin A1c
HER
Human Epidermal Growth Factor Receptor
HIF-1α
hypoxia-inducible factor-1α
HK
hexokinase
IGF1R
insulin growth factor 1 receptor
LDH
lactate dehydrogenase
MDA
Muscular Dystrophy Association
MMP
Matrix Metallopeptidase
MRP1
multidrug resistance-associated protein 1
mTOR
mammalian target of rapamycin
MTX
methotrexate
NCCN
National Comprehensive Cancer Network
OS
overall survival
pCR
Pathologic Complete Response
PDGFR
platelet-derived growth factor receptors
PFS
progression-free survival
PKA
protein kinase A
PR
progesterone receptor
RFS
relapse-free survival
SOD
superoxide dismutase
TAM
tamoxifen
TCA
tricarboxlic acid
TS
thymidylate synthase
Combination
Mechanisms
Metformin
Chemotherapeutic drugs
Differential expression and response to arsenic stress of MRPs and ASAN1 determine sensitivity of classical multidrug-resistant leukemia cells to arsenic trioxide
期刊论文
LEUKEMIA RESEARCH, 2016, 卷号: 50, 页码: 116-122
作者:
Chen, J
;
Cheng, J
;
Yi, J
;
Xie, B
;
Lin, L
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2017/05/08
Arsenic-resistance
Multi-drug resistance
MRP1
MRP2
ASNA1
Leukemia cella
miR-145 sensitizes breast cancer to doxorubicin by targeting multidrug resistance-associated protein-1
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 37, 页码: 59714-59726
作者:
Gao, Man
;
Miao, Lingling
;
Liu, Mingxia
;
Li, Chenggang
;
Yu, Cunzhi
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
breast cancer
MRP1
miRNA
chemoresistance
doxorubicin
MiR-135a and MRP1 play pivotal roles in the selective lethality of phenethyl isothiocyanate to malignant glioma cells
期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2016, 卷号: 6, 期号: 5, 页码: 957-972
作者:
Zhang, Taolan
;
Shao, Yingying
;
Chu, Tang-Yuan
;
Huang, Hsuan-Shun
;
Liou, Yu-Ligh
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/03
MRP1
Phenethyl isothiocyanate
glioma
miR-135a
selective lethality
MRP1和PGC-1α在铅致睾丸支持细胞线粒体毒性中的作用及机制研究
学位论文
2016
作者:
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
醋酸铅
线粒体
睾丸支持细胞
MRP1
PGC-1α
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