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科研机构
上海药物研究所 [3]
复旦大学上海医学院 [3]
高能物理研究所 [1]
山东大学 [1]
中南大学 [1]
武汉大学 [1]
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期刊论文 [11]
发表日期
2018 [11]
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The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors
期刊论文
Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842
作者:
Wang, Xinyi
;
Ai, Jing
;
Liu, Hongyan
;
Peng, Xia
;
Chen, Hui
收藏
  |  
浏览/下载:135/0
  |  
提交时间:2019/01/08
1,4-Diaryl-2-azetidinone
Combretastatin A-4
Tubulin polymerization
Antitumor
C11, a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor, suppresses breast cancer metastasis and angiogenesis
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Chen, Zhuo
;
Tong, Lin-Jiang
;
Tang, Bai-You
;
Liu, Hong-Yan
;
Wang, Xin
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2019/01/08
A Novel 2-Phenylamino-Quinazoline-Based Compound Expands the Neural Stem Cell Pool and Promotes the Hippocampal Neurogenesis and the Cognitive Ability of Adult Mice
期刊论文
STEM CELLS, 2018, 卷号: 36, 期号: 8, 页码: 1273-1285
作者:
Lu, Hui
;
Cheng, Gang
;
Hong, Feng
;
Zhang, Lei
;
Hu, Youhong
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
Neural stem cells
Notch signaling pathway
Hes5
Adult hippocampal neurogenesis
Learning and memory
2-phenylamino-quinazoline
FOXQ1/NDRG1 axis exacerbates hepatocellular carcinoma initiation via enhancing crosstalk between fibroblasts and tumor cells
期刊论文
CANCER LETTERS, 2018, 卷号: 417
作者:
Luo, Qin
;
Wang, Chao-Qun
;
Yang, Lu-Yu
;
Gao, Xiao-Mei
;
Sun, Hao-Ting
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Hepatocellular carcinoma
Cancer associated fibroblast
Initiation
Forkhead box Q1
N-myc downstream-regulated gene 1
The impact of cancer-associated fibroblasts on major hallmarks of pancreatic cancer
期刊论文
THERANOSTICS, 2018, 卷号: 8, 期号: 18
作者:
Sun, Qiqing
;
Zhang, Bo
;
Hu, Qiangsheng
;
Qin, Yi
;
Xu, Wenyan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/05
pancreatic cancer
tumor microenvironment
hallmarks of cancer
cancer-associated fibroblast
Cancer-Associated Fibroblasts in Pancreatic Cancer: Should They Be Deleted or Reeducated?
期刊论文
INTEGRATIVE CANCER THERAPIES, 2018, 卷号: 17, 期号: 4
作者:
Qu, Chao
;
Wang, Qing
;
Meng, Zhiqiang
;
Wang, Peng
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
cancer-associated fibroblast
pancreatic cancer
curcumin
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Molecular mechanism of gd@c-82(oh)(22) increasing collagen expression: implication for encaging tumor
期刊论文
Biomaterials, 2018, 卷号: 152, 页码: 24-36
作者:
Liu, Jing
;
Kang, Seung-gu
;
Wang, Peng
;
Wang, Yue
;
Lv, Xiaonan
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/04/23
Cancer therapeutics
Fibrosarcoma cells
Molecular dynamics
Gd-metallofullerenol
Tnf receptors
Caging cancer cells
FSP1-positive fibroblasts are adipogenic niche and regulate adipose homeostasis
期刊论文
PLOS BIOLOGY, 2018, 卷号: 16, 期号: 8, 页码: e2001493
作者:
Zhan, Rui
;
Gao, Yuan
;
Zhao, Xiaotong
;
Gao, Mei
;
Wu, Yanjun
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/04/28
Matrix Metalloproteinases
Adipocyte Differentiation
Insulin-resistance
In-vivo
Tissue
Cancer
White
Fat
Obesity
Cells
Upregulation of Fibroblast Growth Factor 19 Is Associated with the Initiation of Colorectal Adenoma
期刊论文
Digestive Diseases, 2018
作者:
Wang D.
;
Zhang J.
;
Li Z.
;
Han J.
;
Gao Y.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Biological marker
Colorectal adenoma
Colorectal cancer
Fibroblast growth factor 19
Fibroblast growth factor receptor 4
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