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上海药物研究所 [8]
兰州大学 [3]
暨南大学 [3]
厦门大学 [2]
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期刊论文 [27]
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Analysis of Four Types of Leukemia Using Gene Ontology Term and Kyoto Encyclopedia of Genes and Genomes Pathway Enrichment Scores
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2020, 卷号: 23, 期号: 4, 页码: 295-303
作者:
Lu, Jing
;
Zhang, YuHang
;
Wang, ShaoPeng
;
Bi, Yi
;
Huang, Tao
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
Leukemia
protein-drug interactions
GO term
KEGG pathway
enrichment score
mRMR
Xanthohumol, a Prenylated Flavonoid from Hops, Induces Caspase-Dependent Degradation of Oncoprotein BCR-ABL in K562 Cells
期刊论文
ANTIOXIDANTS, 2019, 卷号: 8, 期号: 9
作者:
Lu, Xuxiu
;
Geng, Jiajia
;
Zhang, Jinman
;
Miao, Jinlai
;
Liu, Ming
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/10/29
K562
xanthohumol
BCR-ABL
degradation
autophagy
caspase
Xanthohumol, a Prenylated Flavonoid from Hops, Induces Caspase-Dependent Degradation of Oncoprotein BCR-ABL in K562 Cells
期刊论文
ANTIOXIDANTS, 2019, 卷号: 8, 期号: 9
作者:
Lu, Xuxiu
;
Geng, Jiajia
;
Zhang, Jinman
;
Miao, Jinlai
;
Liu, Ming
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/10/29
K562
xanthohumol
BCR-ABL
degradation
autophagy
caspase
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
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  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Role and Mechanism of the Interaction of BCR-ABL with E3 Ligase c-CBL in Targeting Therapy of Chronic Myelogenous Leukemia
期刊论文
Zhongguo shi yan xue ye xue za zhi, 2017, 卷号: 25, 期号: 1, 页码: 42-49
作者:
Mao, Jian-Hua
;
Huang, Qiu-Hua
;
Liu, Ping
;
Luo, Cheng
;
Xi, Xiao-Dong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
The optimal dose of arsenic trioxide induced opposite efficacy in autophagy between K562 cells and their initiating cells to eradicate human myelogenous leukemia
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2017, 卷号: 196, 页码: 29-38
作者:
Guo, Zhenzhen[1]
;
Meng, Mingjing[2]
;
Geng, Shengnan[3]
;
Du, Zhenhua[4]
;
Zheng, Yaqiu[5]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
Arsenic trioxide
Chronic myelogenous leukemia (CML)
Leukemiainitiating cells (LICs)
Autophagy
Senescence
Role and Mechanism of the Interaction of BCR-ABL with E3 Ligase c-CBL in Targeting Therapy of Chronic Myelogenous Leukemia
期刊论文
Journal of Experimental Hematology, 2017, 卷号: 25, 期号: 1, 页码: 42-49
作者:
Mao Jianhua
;
Huang Qiuhua
;
Liu Ping
;
Luo Cheng
;
Xi Xiaodong
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
BCR-ABL
c-CBL
BCR-ABL
c-CBL
chronic myelogenous leukemia
arsenic
targeting therapy
Biosensing of BCR/ABL fusion gene using an intensity-interrogation surface plasmon resonance imaging system
期刊论文
OPTICS COMMUNICATIONS, 2016, 卷号: 377, 页码: 24-32
作者:
Wu, Jiangling
;
Huang, Yu
;
Bian, Xintong
;
Li, DanDan
;
Cheng, Quan
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2018/03/15
Surface plasmon resonance imaging
Gold microarray
DNA hybridization
BCR/ABL fusion gene
Noncoding rnas and their functional involvement in regulation of chronic myeloid leukemia
期刊论文
Briefings in functional genomics, 2016, 卷号: 15, 期号: 3, 页码: 239-248
作者:
Wang, Xuefei
;
Chen, Ke
;
Guo, Guijie
;
Chen, Ji-Long
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/05/09
Cml
Cancer
Micrornas
Lncrnas
Bcr-abl
Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Leukemia
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 5, 页码: 1984-2004
作者:
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2017/11/06
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