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科研机构
中南大学 [11]
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期刊论文 [11]
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Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Decreased expression of mitochondrial aldehyde dehydrogenase‐2 induces liver injury via activation of the mitogen‐activated protein kinase pathway
期刊论文
Transplant International, 2016, 卷号: 29, 期号: 1, 页码: 98-107
作者:
Zhong, Zibiao
;
Ye, Shaojun
;
Xiong, Yan
;
Wu, Lianxi
;
Zhang, Meng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
apoptosis
brain death
mitochondrial aldehyde dehydrogenase 2
mitogen‐activated protein kinase pathway
Promyelocytic leukemia protein induces arsenic trioxide resistance through regulation of aldehyde dehydrogenase 3 family member A1 in hepatocellular carcinoma
期刊论文
Cancer Letters, 2015, 卷号: 366, 期号: 1, 页码: 112-122
作者:
Zhang, Xin
;
Yang, Xin-Rong
;
Sun, Chao
;
Hu, Bo
;
Sun, Yun-Fan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/03
HCC
hepatocellular carcinoma
ATO
arsenic trioxide
APL
acute promyelocytic leukemia
PML
promyelocytic leukemia protein
RARα
retinoic acid receptor α
ALDH3A1
aldehyde dehydrogenase 3 family member A1
qRT-PCR
quantitative real-time reverse transcriptase polymerase chain reaction
TMA
tissue microarray
OS
overall survival
TTR
time to recurrence
DMEM
Dulbecco's modified Eagle's medium
CB7
1-[(4-fluorophenyl) sulfonyl]-2-methyl-1H-benzimidazole
siRNA
small interfering RNA
shRNA
small hairpin RNA
GFP
green fluorescent protein
MTT
3-(4,5-dimethylthiazol2-yl)-2,5-diphenyltetrazolium bromide
ChIP
chromatin immunoprecipitation
ORF
open reading frame
ROS
reactive oxygen species
DCFH-DA
2,7-dichlorfluorescein-diacetate
AFP
α-fetoprotein
ALT
alanine aminotransferase
TTP
time to progression
GO
gene ontology
NFκB
nuclear factor kappa-light-chain-enhancer of activated B cells
Bcl-2
B-cell lymphoma 2
Promyelocytic leukemia protein
Aldehyde dehydrogenase 3 family member A1
Reactive oxygen species
Tumor growth
Drug resistance
Cancer stem cell vaccine inhibits metastases of primary tumors and induces humoral immune responses against cancer stem cells.
期刊论文
OncoImmunology, 2015, 卷号: 4, 期号: 3, 页码: e990767
作者:
Lu, Lin
;
Tao, Huimin
;
Chang, Alfred E.
;
Hu, Yangyang
;
Shu, Guoshun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
ALDH, aldehyde dehydrogenase
CSC, cancer stem cell
CSC-DC, CSC lysate-pulsed dendritic cell
DC, dendritic cell
H-DC
RT, radiation therapy
antitumor immunity
cancer stem cell
dendritic cell
heterogeneous
metastasis
qRT-PCR, real time quantitative PCR
unsorted tumor cell lysate-pulsed dendritic cell
vaccine
Alda-1 reduces cerebral ischemia/reperfusion injury in rat through clearance of reactive aldehydes
期刊论文
Naunyn-Schmiedeberg's Archives of Pharmacology, 2014, 卷号: 387, 期号: 1, 页码: 87-94
作者:
Fu, Si-Hai
;
Zhang, Hong-Feng
;
Yang, Zhong-Bao
;
Li, Ting-Bo
;
Liu, Bin
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/03
Alda-1
Ischemia/reperfusion
Aldehyde dehydrogenase 2
Reactive aldehydes
Brain
Mitochondrial aldehyde dehydrogenase, a potential drug target for protection of heart and brain from ischemia/reperfusion injury.
期刊论文
Current Drug Targets, 2014, 卷号: 15, 期号: 10, 页码: 948-955
作者:
Luo, Xiu-Ju
;
Liu, Bin
;
Ma, Qi-Lin
;
Peng, Jun*
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
4-hydroxy-2-nonenal (4-HNE)
Alda-1
Aldehyde
Ischemia/reperfusion injury
Mitochondrial aldehyde dehydrogenase (ALDH2)
Oxidative stress
Alpha lipoic acid protects heart against myocardial ischemia-reperfusion injury through a mechanism involving aldehyde dehydrogenase 2 activation
期刊论文
European Journal of Pharmacology, 2012, 卷号: 678, 期号: 1-3, 页码: 32-38
作者:
Lan He
;
Bin Liu
;
Zhong Dai
;
Hong-Feng Zhang
;
Yi-Shuai Zhang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
Ischemia–reperfusion
Alpha-lipoic acid
ALDH2 (aldehyde dehydrogenase 2)
Hypoxia–reoxygenation
4-HNE (4-hydroxy-2-nonenal)
Comparison of quantum dot technology with conventional immunohistochemistry in examining aldehyde dehydrogenase 1A1 as a potential biomarker for lymph node metastasis of head and neck cancer
期刊论文
European Journal of Cancer, 2012, 卷号: 48, 期号: 11, 页码: 1682-1691
作者:
Xu, Jing
;
Mueller, Susan
;
Nannapaneni, Sreenivas
;
Pan, Lin
;
Wang, Yuxiang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
Aldehyde dehydrogenase 1
Biomarker
Metastasis
Immunohistochemistry
Head and neck cancer
Quantum dot
Nanotechnology
PITX3 gene polymorphism is associated with Parkinson's disease in Chinese population
期刊论文
Brain Research, 2011, 卷号: 1392, 页码: 116-120
作者:
Liu, Jia
;
Sun, Qi-Ying
;
Tang, Bei-Sha
;
Hu, Liang
;
Yu, Ren-He
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/03
Pitx3
Single nucleotide polymorphisms
Parkinson's disease
Meta-analysis
PD
Parkinson's disease
SPD
Sporadic PD
SNpc
Substantia nigra pars compacta
LB
Lewy body
mDA
Midbrain dopaminergic
TH
Tyrosine hydroxylase
AHD2
Aldehyde dehydrogenase
GDNF
Glial cell line derived neurotrophic factor
BDNF
Brain derived neurotrophic factor
LOPD
Late onset PD
EOPD
Early onset PD
RFLP
Restricted fragment length polymorphism
Identification of musashi-1 and ALDH1 as carcinogenesis, progression, and poor-prognosis related biomarkers for gallbladder adenocarcinoma
期刊论文
Cancer Biomarkers, 2010, 卷号: 8, 期号: 3, 页码: 113-121
作者:
Liu, Dong-Cai
;
Yang, Zhu-Lin*
;
Jiang, Song
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Gallbladder neoplasms, gallbladder polyp, chronic cholecystitis, aldehyde dehydrogenase1, musashi-1, immunohistochemistry
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