CORC

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CORC

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Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Wang, Zuo-wei;  Zou, Feng-ming;  Wang, Ao-li;  Yang, Jing;  Jin, Rui
收藏  |  浏览/下载：17/0  |  提交时间：2022/12/22
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing
收藏  |  浏览/下载：77/0  |  提交时间：2021/11/04
Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 7
作者:  Wang, Yi;  Fang, Sui;  Wu, Yan;  Cheng, Xi;  Zhang, Lei-ke
收藏  |  浏览/下载：101/0  |  提交时间：2021/08/17
A robust high-throughput fluorescent polarization assay for the evaluation and screening of SARS-CoV-2 fusion inhibitors 期刊论文
Bioorganic Chemistry, 2021, 卷号: 116, 期号: 7, 页码: 2341-2363
作者:  X. J. Yin;  L. T. Chen;  S. W. Yuan;  L. Liu and Z. Z. Gao
收藏  |  浏览/下载：6/0  |  提交时间：2022/06/13
Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:  Zhou, Yan;  Du, Dao-Hai;  Wang, Jia;  Cai, Xiao-Qing;  Deng, Alicia X.
收藏  |  浏览/下载：102/0  |  提交时间：2020/07/01
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292
作者:  Zhang, Feng-cai;  Sun, Zhong-ya;  Liao, Li-ping;  Zuo, Yu;  Zhang, Dan
收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01
discoveryofnovelcbpbromodomaininhibitorsthroughtrfretbasedhighthroughputscreening 期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 285
作者:  Zhang Fengcai;  Sun Zhongya;  Liao Liping;  Zuo Yu;  Zhang Dan
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01
Integration of micro-fractionation, high-performance liquid chromatography-ultraviolet detector-charged aerosol detector-mass spectrometry analysis and cellular dynamic mass redistribution assay to accelerate alkaloid drug discovery 期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2020, 卷号: 1616
作者:  Wang, Rong;  Liu, Yanfang;  Zhou, Han;  Chen, Yue;  Wang, Jixia
收藏  |  浏览/下载：16/0  |  提交时间：2020/11/25
A Drug with Lipophilicity-Dependent Potency Can Be Metabolically Stable: Discovery of a Potent and Selective Retinoic Acid Receptor-Related Orphan Receptor C2 (RORC2) Inverse Agonist as an Orally Bioavailable Anti-Inflammatory Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 23, 页码: 10412-10414
作者:  Wang, Yibing;  Liu, Hong
收藏  |  浏览/下载：78/0  |  提交时间：2019/01/08
High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1816-1822
作者:  Wang, Jia;  Gong, Grace Qun;  Zhou, Yan;  Lee, Woo-Jeong;  Buchanan, Christina Maree
收藏  |  浏览/下载：84/0  |  提交时间：2019/01/08

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