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科研机构
山东大学 [5]
复旦大学上海医学院 [5]
西安交通大学 [3]
上海药物研究所 [3]
昆明医科大学 [3]
合肥物质科学研究院 [3]
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期刊论文 [42]
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GSK3 beta palmitoylation mediated by ZDHHC4 promotes tumorigenicity of glioblastoma stem cells in temozolomide-resistant glioblastoma through the EZH2-STAT3 axis
期刊论文
ONCOGENESIS, 2022, 卷号: 11
作者:
Zhao, Chenggang
;
Yu, Huihan
;
Fan, Xiaoqing
;
Niu, Wanxiang
;
Fan, Junqi
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2022/12/23
Discovery of IHMT-EZH2-115 as a Potent and Selective Enhancer of Zeste Homolog 2 (EZH2) Inhibitor for the Treatment of B-Cell Lymphomas
期刊论文
J. Med. Chem., 2021
作者:
Qi S(亓爽)
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/12/09
LncRNA UCA1 Antagonizes Arsenic-Induced Cell Cycle Arrest through Destabilizing EZH2 and Facilitating NFATc2 Expression
期刊论文
ADVANCED SCIENCE, 2020, 卷号: 7, 期号: 11, 页码: 1-16
作者:
Dong, Zheng
;
Gao, Ming
;
Li, Changying
;
Xu, Ming
;
Liu, Sijin
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/09/14
arsenic
cell cycle arrest
enhancer of zeste homolog 2 (EZH2)
lncRNA
tumorigenesis
urothelial cancer associated 1 (UCA1)
Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:
Zhou, Yan
;
Du, Dao-Hai
;
Wang, Jia
;
Cai, Xiao-Qing
;
Deng, Alicia X.
收藏
  |  
浏览/下载:102/0
  |  
提交时间:2020/07/01
embryonic ectoderm development
Enhancer of zeste homolog 2
fluorescence polarization
high-throughput screening
homogenous time-resolved fluorescence
inhibitor
polycomb repressive complex 2
EZH2 promotes invasion and tumour glycolysis by regulating STAT3 and FoxO1 signalling in human OSCC cells
期刊论文
Journal of Cellular and Molecular Medicine, 2019
作者:
Zheng M.
;
Cao M.-X.
;
Luo X.-J.
;
Li L.
;
Wang K.
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/11
enhancer of zeste homolog 2
epithelial-mesenchymal transition
FoxO1
invasion
oral squamous cell carcinoma
STAT3
tumour glycolysis
LncRNA SNHG17 promotes gastric cancer progression by epigenetically silencing of p15 and p57
期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: 234, 期号: 4, 页码: 5163-5174
作者:
Zhang, Guohua[1]
;
Xu, Ying[2]
;
Wang, Sijia[3]
;
Gong, Zhigang[4]
;
Zou, Chen[5]
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/24
enhancer of zeste homolog 2 (EZH2)
gastric cancer (GC)
p15
p57
polycomb repressive complex 2 (PRC2)
small nucleolar RNA host gene 17 (SNHG17)
Development of a high-throughput fluorescence polarization assay for the discovery of EZH2-EED interaction inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 302-310
作者:
Zhu, Mao-rong
;
Du, Dao-hai
;
Hu, Jun-chi
;
Li, Lian-chun
;
Liu, Jing-qiu
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  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
PRC2
EZH2
EED
protein-protein interaction
fluorescence polarization
high-throughput screening
apomorphine hydrochloride
oxyphenbutazone
nifedipine
ergonovine maleate
Androgen receptor drives hepatocellular carcinogenesis by activating enhancer of zeste homolog 2-mediated Wnt/beta-catenin signaling
期刊论文
EBIOMEDICINE, 2018, 卷号: 35
作者:
Song, Haibin
;
Yu, Zhuo
;
Sun, Xuehua
;
Feng, Jun
;
Yu, Qi
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Androgen receptor
EZH2
Wnt/beta-catenin signaling
Hepatocarcinogenesis
Epigenetics
EZH2 enhances the invasive capability of renal cell carcinoma cells via activation of STAT3
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 17, 页码: 3621-3626
作者:
Zhang, Dong
;
Yang, Xiao-Jie
;
Luo, Qi-Dong
;
Fu, De-Lai
;
Li, Hong-Liang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/11/26
enhancer of zeste homolog 2
metastasis
signal transducer and activator of transcription 3
renal cell carcinoma
Effect of long non-coding RNA PVT1 on cell proliferation and migration in melanoma
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2018, 卷号: 41, 期号: 3, 页码: 1275-1282
作者:
Chen, Lamei
;
Ma, Dongmei
;
Li, Yuanyuan
;
Li, Xiaoying
;
Zhao, Lei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
melanoma
long non-coding RNA Pvt1 oncogene (non-protein coding)
cell
proliferation
metastasis
enhancer of zeste homolog 2
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