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复旦大学上海医学院 [6]
上海药物研究所 [4]
四川大学 [3]
吉林大学白求恩第一医... [3]
海洋研究所 [2]
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期刊论文 [26]
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Paralichthys olivaceus
MLKL-mediated necroptosis is activated by RIPK1/3 and involved in anti-microbial immunity
期刊论文
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 11
作者:
Hao, Kangwei
;
Xu, Hang
;
Jiang, Shuai
;
Sun, Li
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/04/07
Paralichthys olivaceus
necroptosis
RIPK1
RIPK3
MLKL
immune defense
Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Wang, Zuo-wei
;
Zou, Feng-ming
;
Wang, Ao-li
;
Yang, Jing
;
Jin, Rui
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/22
AZD4547
RIPK1
inhibitors
SIRS model
anti-necroptosis
The pathogenesis of organ fibrosis: Focus on necroptosis
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2022
作者:
Hao, Min
;
Han, Xin
;
Yao, Zhouhui
;
Zhang, Han
;
Zhao, Mengting
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/22
liver fibrosis
lung fibrosis
MLKL
necroptosis
RIPK1
3
tissue fibrosis
Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:
Yang, Xiangbo
;
Lu, Huimin
;
Xie, Hang
;
Zhang, Binbin
;
Nie, Tianqing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/01/18
Binding studies
Drug discovery
Necroptosis
RIPK1 inhibitors
Sepsis
A Conditionally Releasable "Do not Eat Me" CD47 Signal Facilitates Microglia-Targeted Drug Delivery for the Treatment of Alzheimer's Disease
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 10
作者:
Zhang, Lun
;
Liu, Xiao-ge
;
Liu, Dong-qun
;
Yu, Xiao-lin
;
Zhang, Ling-xiao
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/06/15
Alzheimer's Disease
Brain Delivery
Cd47
Microglia
Ripk1
RIPK1 inhibitor ameliorates colitis by directly maintaining intestinal barrier homeostasis and regulating following IECs-immuno crosstalk
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 172, 页码: 16
作者:
Lu, Huimin
;
Li, Heng
;
Fan, Chen
;
Qi, Qing
;
Yan, Yuxi
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
RIPK1 inhibitor
Colitis
Barrier homeostasis
IECs-immunocytes crosstalk
Necroptosis
NF-kappa B
Microglia-derived TNF-alpha mediates endothelial necroptosis aggravating blood brain-barrier disruption after ischemic stroke
期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 18
作者:
Chen, An-Qi
;
Fang, Zhi
;
Chen, Xiao-Lu
;
Yang, Shuai
;
Zhou, Yi-Fan
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2019/10/14
Identification of the Raf kinase inhibitor TAK-632 and its analogues as potent inhibitors of necroptosis by targeting RIPK1 and RIPK3
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 12
作者:
Qin, Xia
;
Hu, Longmiao
;
Fu, Jing
;
Miao, Zhenyuan
;
Li, Zheng-gang
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2019/12/05
Necrostatin-1 Prevents Necroptosis in Brains after Ischemic Stroke via Inhibition of RIPK1-Mediated RIPK3/MLKL Signaling
期刊论文
AGING AND DISEASE, 2019, 卷号: 10, 期号: 4
作者:
Deng, Xu-Xu
;
Li, Shan-Shan
;
Sun, Feng-Yan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
RIPK1
necroptosis
necrostatin-1 (Nec-1)
cerebral stroke
inflammation
neuroprotection
High glucose-induced apoptosis and necroptosis in podocytes is regulated by UCHL1 via RIPK1/RIPK3 pathway
期刊论文
EXPERIMENTAL CELL RESEARCH, 2019, 卷号: 382, 期号: 2-3
作者:
Gao, Hongyang
;
Hu, Yuan
;
Fang, Yili
;
Qi, Chenyang
;
Huang, Jiebo
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/05
Necroptosis
Podocyte injury
RIPK1
RIPK3
UCHL1
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