CORC

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CORC

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Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Wang, Zuo-wei;  Zou, Feng-ming;  Wang, Ao-li;  Yang, Jing;  Jin, Rui
收藏  |  浏览/下载：17/0  |  提交时间：2022/12/22
Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing
收藏  |  浏览/下载：22/0  |  提交时间：2022/01/18
RIPK1 inhibitor ameliorates colitis by directly maintaining intestinal barrier homeostasis and regulating following IECs-immuno crosstalk 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 172, 页码: 16
作者:  Lu, Huimin;  Li, Heng;  Fan, Chen;  Qi, Qing;  Yan, Yuxi
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01
Identification of the Raf kinase inhibitor TAK-632 and its analogues as potent inhibitors of necroptosis by targeting RIPK1 and RIPK3 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 12
作者:  Qin, Xia;  Hu, Longmiao;  Fu, Jing;  Miao, Zhenyuan;  Li, Zheng-gang
收藏  |  浏览/下载：72/0  |  提交时间：2019/12/05
Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis 期刊论文
2019, 卷号: 10
作者:  Hou, Jue;  Ju, Jie;  Zhang, Zili;  Zhao, Cong;  Li, Zhanhui
收藏  |  浏览/下载：14/0  |  提交时间：2020/01/03
Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNF alpha and ROS production 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 4, 页码: 1995-2008
作者:  Yu, Xinfang;  Deng, Qipan;  Li, Wei;  Xiao, Lanbo;  Luo, Xiangjian
收藏  |  浏览/下载：59/0  |  提交时间：2015/06/29
Drug discovery against tumor metastasis：identification of 5--7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as a new class of RIPK1 inhibitors,which showed potent activity in a tumor metastasis model 会议论文
第11届世界华人药物化学研讨会（ISCMC 2018）, 中国河南郑州, 2018
作者:  Yueshan Li;  Yu Xiong;  Shengyong Yang
收藏  |  浏览/下载：3/0  |  提交时间：2019/02/25

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