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Broad targeting of triptolide to resistance and sensitization for cancer therapy 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:  Hou, Zhen-yan;  Tong, Xiao-pei;  Peng, Yong-bo;  Zhang, Bi-Kui*;  Yan, Miao*
收藏  |  浏览/下载:50/0  |  提交时间:2019/12/03
ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  
Marine-derived chromopeptide A, a novel class I HDAC inhibitor, suppresses human prostate cancer cell proliferation and migration 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 4, 页码: 551-560
作者:  Sun, Jing-ya;  Wang, Ji-dong;  Wang, Xin;  Liu, Hong-chun;  Zhang, Min-min
收藏  |  浏览/下载:42/0  |  提交时间:2019/01/08
marinederivedchromopeptideaanovelclassihdacinhibitorsuppresseshumanprostatecancercellproliferationandmigration 期刊论文
actapharmacologicasinica, 2017, 卷号: 38, 期号: 4, 页码: 551
作者:  Sun Jingya;  Wang Jidong;  Wang Xin;  Liu Hongchun;  Zhang Minmin
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/01
城市污泥中有毒有机污染物的生物毒理效应及优控污染物甄别 学位论文
博士, 北京: 中国科学院研究生院, 2013
刘操
收藏  |  浏览/下载:50/0  |  提交时间:2014/10/28
A progestin (17 alpha,20 beta-dihydroxy-4-pregnen-3-one) stimulates early stages of spermatogenesis in zebrafish 期刊论文
http://dx.doi.org/10.1016/j.ygcen.2013.01.005, 2013
Chen, Shi X.; Bogerd, Jan; Schoonen, Natasja E.; Martijn, Joran; de Waal, Paul P.; Schulz, Rudiger W.; 陈仕玺
收藏  |  浏览/下载:3/0  |  提交时间:2015/07/22
The suppression of prostate lncap cancer cells growth by selenium nanoparticles through akt/mdm2/ar controlled apoptosis 期刊论文
Biomaterials, 2011, 卷号: 32, 期号: 27, 页码: 6515-6522
作者:  Kong, Ling;  Yuan, Qing;  Zhu, Huarui;  Li, Ying;  Guo, Quanyi
收藏  |  浏览/下载:19/0  |  提交时间:2019/04/23
Structural and functional insights into nuclear receptor signaling 期刊论文
http://dx.doi.org/10.1016/j.addr.2010.08.007, 2010
Jin, Lihua; Li, Yong; 金利华; 李勇
收藏  |  浏览/下载:5/0  |  提交时间:2015/07/22
Effects of extract of Buddleja officinalis eye drops on androgen receptors of lacrimal gland cells of castrated rats with dry eye 期刊论文
International Journal of Ophthalmology, 2010, 卷号: 3, 期号: 1, 页码: 203-208
作者:  Peng, Qing-Hua*;  Yao, Xiao-Lei;  Wu, Quan-Long;  Tan, Han-Yu;  Zhang, Jing-Rong
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/27
Pristimerin induces apoptosis by targeting the proteasome in prostate cancer cells 期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2008, 卷号: 103, 期号: 1, 页码: 234-244
作者:  Li, Lihua;  Yang, Huanjie;  Landis-Piwowar, Kristin R.;  Lu, Dayan;  Yuan, Ping
收藏  |  浏览/下载:14/0  |  提交时间:2017/04/13
Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice 期刊论文
CANCER RESEARCH, 2006, 卷号: 66, 期号: 9, 页码: 4758-4765
作者:  Yang, HJ;  Chen, D;  Cui, QZC;  Yuan, X;  Dou, QP
收藏  |  浏览/下载:8/0  |  提交时间:2017/04/13


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