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科研机构
厦门大学 [2]
上海药物研究所 [2]
武汉植物园 [2]
北京大学 [1]
高能物理研究所 [1]
中南大学 [1]
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期刊论文 [10]
学位论文 [1]
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2018 [1]
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2010 [2]
2008 [1]
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Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
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浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Marine-derived chromopeptide A, a novel class I HDAC inhibitor, suppresses human prostate cancer cell proliferation and migration
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 4, 页码: 551-560
作者:
Sun, Jing-ya
;
Wang, Ji-dong
;
Wang, Xin
;
Liu, Hong-chun
;
Zhang, Min-min
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
HDAC
chromopeptide A
FK228
human prostate cancer
cell cycle arrest
apoptosis
cancer cell migration
PC3 xenograft model
marinederivedchromopeptideaanovelclassihdacinhibitorsuppresseshumanprostatecancercellproliferationandmigration
期刊论文
actapharmacologicasinica, 2017, 卷号: 38, 期号: 4, 页码: 551
作者:
Sun Jingya
;
Wang Jidong
;
Wang Xin
;
Liu Hongchun
;
Zhang Minmin
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
HISTONE DEACETYLASE INHIBITORS
ANDROGEN DEPRIVATION THERAPY
ROMIDEPSIN
VORINOSTAT
EXPRESSION
RESISTANCE
TRIAL
DEPSIPEPTIDE
MITOXANTRONE
ABIRATERONE
HDAC
chromopeptide A
FK228
human prostate cancer
cell cycle arrest
apoptosis
cancer cell migration
PC3 xenograft model
城市污泥中有毒有机污染物的生物毒理效应及优控污染物甄别
学位论文
博士, 北京: 中国科学院研究生院, 2013
刘操
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2014/10/28
城市污泥
生物测试
化学分析
生物毒性
生态风险
北京
Sewage sludge
Bioassay
Chemical analysis
Biological toxicity
Ecological risk
Beijing
A progestin (17 alpha,20 beta-dihydroxy-4-pregnen-3-one) stimulates early stages of spermatogenesis in zebrafish
期刊论文
http://dx.doi.org/10.1016/j.ygcen.2013.01.005, 2013
Chen, Shi X.
;
Bogerd, Jan
;
Schoonen, Natasja E.
;
Martijn, Joran
;
de Waal, Paul P.
;
Schulz, Rudiger W.
;
陈仕玺
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/07/22
ANTI-MULLERIAN HORMONE
CATFISH CLARIAS-GARIEPINUS
RAINBOW-TROUT TESTIS
PRIMORDIAL GERM-CELL
I MESSENGER-RNA
DIFFERENTIAL EXPRESSION
AFRICAN CATFISH
JAPANESE EEL
IGF-I
PHARMACOLOGICAL CHARACTERIZATION
The suppression of prostate lncap cancer cells growth by selenium nanoparticles through akt/mdm2/ar controlled apoptosis
期刊论文
Biomaterials, 2011, 卷号: 32, 期号: 27, 页码: 6515-6522
作者:
Kong, Ling
;
Yuan, Qing
;
Zhu, Huarui
;
Li, Ying
;
Guo, Quanyi
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/04/23
Selenium nanoparticles
Prostate cancer
Apoptosis
Androgen receptor
Structural and functional insights into nuclear receptor signaling
期刊论文
http://dx.doi.org/10.1016/j.addr.2010.08.007, 2010
Jin, Lihua
;
Li, Yong
;
金利华
;
李勇
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/07/22
LIGAND-BINDING DOMAIN
REV-ERB-ALPHA
INDEPENDENT TRANSCRIPTIONAL ACTIVATION
TRANS-RETINOIC ACID
PREGNANE-X-RECEPTOR
CRYSTAL-STRUCTURE
ANDROGEN RECEPTOR
PPAR-GAMMA
MINERALOCORTICOID RECEPTOR
MOLECULAR RECOGNITION
Effects of extract of Buddleja officinalis eye drops on androgen receptors of lacrimal gland cells of castrated rats with dry eye
期刊论文
International Journal of Ophthalmology, 2010, 卷号: 3, 期号: 1, 页码: 203-208
作者:
Peng, Qing-Hua*
;
Yao, Xiao-Lei
;
Wu, Quan-Long
;
Tan, Han-Yu
;
Zhang, Jing-Rong
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/27
androgen receptors
androgen-like activity
castrate
dry eye
eye drops
lacrimal gland
the extract of Buddleja officinalis
Pristimerin induces apoptosis by targeting the proteasome in prostate cancer cells
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2008, 卷号: 103, 期号: 1, 页码: 234-244
作者:
Li, Lihua
;
Yang, Huanjie
;
Landis-Piwowar, Kristin R.
;
Lu, Dayan
;
Yuan, Ping
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2017/04/13
pristimerin
proteasome inhibition
natural compounds
apoptosis
prostate cancer
Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice
期刊论文
CANCER RESEARCH, 2006, 卷号: 66, 期号: 9, 页码: 4758-4765
作者:
Yang, HJ
;
Chen, D
;
Cui, QZC
;
Yuan, X
;
Dou, QP
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2017/04/13
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