ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  

angiogenesis  aquaporin 9  hippocampus  intracranial hemorrhage  neuronal loss  

ChIP  chromatin immunoprecipitation  DFS  disease-free survival  EGF  epidermal growth factor  EMT  epithelial-mesenchymal transition  GSK-3β  glycogen synthase kinase-3β  HCC  hepatocellular carcinoma  HDAC3  histone deacetylase 3  IF  immunofluorescence  IHC  immunohistochemistry  NCoR  nuclear receptor corepressor  OS  overall survival  PCR  polymerase chain reaction  TBL1  transducin-beta-like protein 1  TBLR1  transducing-beta-like 1 X-linked receptor 1  TF  transcriptional factor  shSIK1  small hairpin RNA targeting SIK1  Salt-inducible kinase 1  Twist1  Epithelial-mesenchymal transition  β-catenin  Silencing mediator for retinoid  Thyroid receptors  

integrin-linked kinase  glycogen synthase kinase 3 beta  human peritoneal mesothelial cells  epithelial-mesenchymal transition  peritoneal dialysis  

BP  Bipolar disorder  CA  Cornu ammonis  CNS  Central nervous system  CPP  3-(2-carboxypiperazin-4-yl) propyl-1-phosphonic acid  CT  Carboxyterminal  DG  Dentate gyrus  DGCs  Dentate granule cells  DISC  Disrupted-in-schizophrenia 1  Dixdc1  Dix domain containing 1  FEZ1  Elongation Protein Zeta-1  Fz  Frizzled  GABA  γ-aminobutyric acid  Grb2  Growth factor receptor bound protein 2  GSK3β  Glycogen synthase kinase 3β  KCC2  K+–Cl− co-transporter 2  kDa  kilodalton  KIF5B  Kinesin family members 5B  LEF/TCF  Lymphoid enhancer factor/T cell factor  LIS1  Lissencephaly-1  LRP5/6  Lipoprotein receptor-related protein 5/6  MDD  Major depressive disorder  MK-801  (5R,10S)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]c-cyclohepten-5-10-imine hydrogen maleate  MW  Molecular weight  NDEL1  Nuclear distribution gene E-like homolog 1  NKCC1  Na+-K+-Cl− co-transporter1  NLS  Nuclear localization signal  NMDA-R  N-methyl-d-aspartate-type glutamate receptor  d  NSCs  Neural stem cells  NT  Unique amino  NT-3  Neutrophins-3  OB  Olfactory bulbs  PTEN  Phosphatase and tensin homolog deleted on chromosome ten  RNAi  RNA interference  RYK  Related to tyrosine kinase  SGZ  Subgranular zone  shRNA  Short hairpin RNA  siRNA  Small interference RNA  SVZ  Subventricular zone  SZ  Schizophrenia  DISC1  Signaling pathway  Neurogenesis  DG  Hippocampus