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CORC

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Design, Synthesis, and Structure-Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 页码: 2353-2371
作者:  Xun, Qiuju[1];  Zhang, Zhang[2];  Luo, Jinfeng[3];  Tong, Linjiang[4];  Huang, Minhao[5]
收藏  |  浏览/下载：25/0  |  提交时间：2019/04/22
Design, Synthesis, and Structure-Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitors 期刊论文
2018, 卷号: 61, 期号: 6, 页码: 2353
作者:  Xun, Qiuju[1,2];  Zhang, Zhang[3];  Luo, Jinfeng[1];  Tong, Linjiang[6];  Huang, Minhao[1,2]
收藏  |  浏览/下载：16/0  |  提交时间：2019/12/10
YL143, a novel mutant selective irreversible EGFR inhibitor, overcomes EGFR(L858R, T790M)-mutant resistance in vitro and in vivo 期刊论文
2018, 卷号: 7, 期号: 4, 页码: 1430
作者:  Zhang, Zhang[1];  Zou, Jian[1];  Yu, Lei[2,3];  Luo, Jinfeng[3];  Li, Yan[4]
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/10
A Preliminary Study on the Infrared Spectra Characteristics of Radix Chuanmingshinis Violacei 期刊论文
2018, 卷号: 9, 期号: 4, 页码: 31-34
作者:  Xingguo ZHANG[1];  Anhui HAO[1];  Kunlun LI[1];  Guanghua LU[1];  Yajie LIU[2]
收藏  |  浏览/下载：7/0  |  提交时间：2019/12/16
Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2-a]pyrazin-3-ylethynyl)-4-isopropyl-N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2 期刊论文
2018, 卷号: 61, 期号: 17, 页码: 7977
作者:  Wang, Zhen[1,2];  Zhang, Yali[3];  Pinkas, Daniel M.[7];  Fox, Alice E.[7];  Luo, Jinfeng[2]
收藏  |  浏览/下载：27/0  |  提交时间：2019/12/17
Discovery of JND3229 as a New EGFR(C797S) Mutant Inhibitor with In Vivo Monodrug Efficacy 期刊论文
2018, 卷号: 9, 期号: 11, 页码: 1123
作者:  Lu, Xiaoyun[1];  Zhang, Tao[2,6,7];  Zhu, Su-Jie[3,4];  Xun, Qiuju[5];  Tong, Lingjiang[2]
收藏  |  浏览/下载：24/0  |  提交时间：2019/12/23
HMGB1 silencing in macrophages prevented their functional skewing and ameliorated EAM development: Nuclear HMGB1 may be a checkpoint molecule of macrophage reprogramming 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 卷号: 56, 页码: 277-284
作者:  Jiang, Yuanyuan[1];  Chen, Rong[2];  Shao, Xiaoyi[3];  Ji, Xiaoyun[4];  Lu, Hongxiang[5]
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/24
Targeting EGFR(L858R/T790M) and EGFR(L858R/T790M/C797S) resistance mutations in NSCLC: Current developments in medicinal chemistry 期刊论文
2018, 卷号: 38, 期号: 5, 页码: 1550
作者:  Lu, Xiaoyun[1];  Yu, Lei[2];  Zhang, Zhang[1];  Ren, Xiaomei[1];  Smaill, Jeff B.[3,4]
收藏  |  浏览/下载：9/0  |  提交时间：2019/12/06
Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in MiceSCI原文链接 期刊论文
2018, 卷号: 11
作者:  Zhu, Chengwen[1,2,3];  Cheng, Cheng[1,2,3,4];  Wang, Yanfei[5,6];  Muhammad, Waqas[2,7];  Liu, Shuang[8]
收藏  |  浏览/下载：9/0  |  提交时间：2020/01/04
A structure-guided optimization of pyrido[2,3-d]pyrimidin-7-ones as selective inhibitors of EGFR(L858R/T790M) mutant with improved pharmacokinetic properties 期刊论文
2017, 卷号: 126, 期号: [db:dc_citation_issue], 页码: 1107
作者:  Yu, Lei[1,2];  Huang, Minhao[1,2];  Xu, Tianfeng[1,2];  Tong, Linjiang[4];  Yan, Xiao-e[5,6]
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/03

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