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期刊论文 [28]
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Discovery of novel DNA methyltransferase 3A inhibitors via structure-based virtual screening and biological assays
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 2, 页码: 342-346
作者:
Shao, Zhiyuan
;
Xu, Pan
;
Xu, Wen
;
Li, Linjuan
;
Liu, Shien
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Epigenetics
DNMT3A inhibitors
Virtual screening
Molecular docking
Gene-gene and gene-sex epistatic interactions of DNMT1, DNMT3A and DNMT3B in autoimmune thyroid disease
期刊论文
ENDOCRINE JOURNAL, 2016, 卷号: 63, 期号: 7
作者:
Cai, Tian-tian
;
Zhang, Jian
;
Wang, Xuan
;
Song, Rong-hua
;
Qin, Qiu
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/05
DNA methyltransferases (DNMTs)
Autoimmune thyroid diseases
Graves' disease
Hashimoto's thyroiditis
Single nucleotide polymorphism (SNP)
Loss of Dnmt3b accelerates MLL-AF9 leukemia progression
期刊论文
LEUKEMIA, 2016
Zheng, Y.
;
Zhang, H.
;
Wang, Y.
;
Li, X.
;
Lu, P.
;
Dong, F.
;
Pang, Y.
;
Ma, S.
;
Cheng, H.
;
Hao, S.
;
Tang, F.
;
Yuan, W.
;
Zhang, X.
;
Cheng, T.
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
ACUTE MYELOID-LEUKEMIA
HEMATOPOIETIC STEM-CELLS
GENE-EXPRESSION PROFILES
HEMATOLOGICAL MALIGNANCIES
DNA METHYLTRANSFERASE-1
POTENT INHIBITOR
CANCER
METHYLATION
TRANSFORMATION
MUTATIONS
TET-mediated DNA demethylation controls gastrulation by regulating Lefty-Nodal signalling
期刊论文
NATURE, 2016
Dai, Hai-Qiang
;
Wang, Bang-An
;
Yang, Lu
;
Chen, Jia-Jia
;
Zhu, Guo-Chun
;
Sun, Mei-Ling
;
Ge, Hao
;
Wang, Rui
;
Hapman, Deborah L. C.
;
Tang, Fuchou
;
Sun, Xin
;
Xu, Guo-Liang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/12/03
ONE-STEP GENERATION
EARLY MOUSE EMBRYO
RNA-SEQ
MAMMALIAN DEVELOPMENT
SINGLE-CELL
METHYLTRANSFERASES DNMT3A
CRE RECOMBINASE
GERM-CELLS
METHYLATION
GENOME
Global DNA methylation and related mRNA profiles in sheep oocytes and early embryos derived from pre-pubertal and adult donors
期刊论文
Animal Reproduction Science, 2016, 卷号: 164, 页码: 144-151
作者:
Y. Fang, X. S. Zhang, J. L. Zhang, R. Z. Zhong and D. W. Zhou
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2016/11/25
Ancestral TCDD exposure promotes epigenetic transgenerational inheritance of imprinted gene Igf2: Methylation status and DNMTs
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2015, 卷号: 289, 期号: 2, 页码: 193-202
作者:
Ma, Jing
;
Chen, Xi
;
Liu, Yanan
;
Xie, Qunhui
;
Sun, Yawen
收藏
  |  
浏览/下载:148/0
  |  
提交时间:2016/03/10
2
Epigenetic transgenerational inheritance
Somatic tissue
Imprinted gene
Differentially methylated region
DNA methyltransferase
3
7
8-Tetrachlorodibenzo-p-Dioxin
Structural insight into autoinhibition and histone H3-induced activation of DNMT3A
期刊论文
NATURE, 2015, 卷号: 517, 期号: 7536, 页码: 640-U281
作者:
Guo, X
;
Wang, L
;
Li, J
;
Ding, ZY
;
Xiao, JX
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2015/07/22
Identifying Novel Selective Non-Nucleoside DNA Methyltransferase 1 Inhibitors through Docking-Based Virtual Screening
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 57, 期号: 21, 页码: 9028-9041
作者:
Chen, Shijie
;
Wang, Yulan
;
Zhou, Wen
;
Li, Shanshan
;
Peng, Jianlong
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Regulation of DNA methylation turnover at LTR retrotransposons and imprinted loci by the histone methyltransferase Setdb1
期刊论文
proceedings of the national academy of sciences of the united states of america, 2014
Leung, Danny
;
Du, Tingting
;
Wagner, Ulrich
;
Xie, Wei
;
Lee, Ah Young
;
Goyal, Preeti
;
Li, Yujing
;
Szulwach, Keith E.
;
Jin, Peng
;
Lorincz, Matthew C.
;
Ren, Bing
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/16
epigenomics
histone modifications
repetitive elements
5-hydroxymethylcytosine
EMBRYONIC STEM-CELLS
PRIMORDIAL GERM-CELLS
CONTROL REGIONS
MAMMALIAN DNA
5-HYDROXYMETHYLCYTOSINE
TET1
5-METHYLCYTOSINE
DEMETHYLATION
TRANSCRIPTION
CONVERSION
Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote
期刊论文
cell stem cell, 2014
Guo, Fan
;
Li, Xianlong
;
Liang, Dan
;
Li, Tong
;
Zhu, Ping
;
Guo, Hongshan
;
Wu, Xinglong
;
Wen, Lu
;
Gu, Tian-Peng
;
Hu, Boqiang
;
Walsh, Colum P.
;
Li, Jinsong
;
Tang, Fuchou
;
Xu, Guo-Liang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/10
BASE EXCISION-REPAIR
MOUSE PREIMPLANTATION DEVELOPMENT
EMBRYONIC STEM-CELLS
METHYLTRANSFERASES DNMT3A
METHYLATION LANDSCAPE
PATERNAL GENOME
5-HYDROXYMETHYLCYTOSINE
TET
DYNAMICS
TDG
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