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Solubilization, purification, and ligand binding characterization of G protein-coupled receptor SMO in native membrane bilayer using styrene maleic acid copolymer
期刊论文
PEERJ, 2022, 卷号: 10
作者:
Zhu, Lina
;
Zhao, Hongxin
;
Wang, Yizhuo
;
Yu, Chuandi
;
Liu, Juanjuan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/12/23
GPCR
Dissociation constant
Detergents
Styrene maleic acid copolymer nanodiscs
Smoothened receptors
NMR
PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 7, 页码: 10
作者:
Yang, Jun
;
Wang, Juan
;
Liu, Yuan
;
Zhang, Yu
;
Huang, Wenjing
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/08/17
Dual activation of Hedgehog and Wnt/beta-catenin signaling pathway caused by downregulation of SUFU targeted by miRNA-150 in human gastric cancer
期刊论文
AGING-US, 2021, 卷号: 13, 期号: 7, 页码: 10749-10769
作者:
Peng, Yin
;
Zhang, Xiaojing
;
Lin, Huijuan
;
Deng, Shiqi
;
Qin, Ying
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/12/01
miRNA-150
SUFU
Wnt/beta-catenin
hedgehog
EMT
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:
Liu, Xiaohua
;
Zhang, Yu
;
Li, Yalei
;
Wang, Juan
;
Ding, Huaqian
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/05/24
Medulloblastoma
Hedgehog signaling
pathway
Drug resistance
GLI
BRD4
SUFU mediates EMT and Wnt/beta-catenin signaling pathway activation promoted by miRNA-324-5p in human gastric cancer
期刊论文
CELL CYCLE, 2020, 页码: 14
作者:
Peng, Yin
;
Zhang, Xiaojing
;
Lin, Huijuan
;
Deng, Shiqi
;
Qin, Ying
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/12/10
miRNA-324-5p
SUFU negative regulator of hedgehog signaling
Wnt/beta-catenin
EMT
USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines
期刊论文
FEBS JOURNAL, 2020, 页码: 18
作者:
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Xiong, Muya
;
Zhu, Mengying
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2020/12/24
colorectal cancer
HDX-MS
inhibitor
USP25
USP28
Vismodegib
Analysis of Four Types of Leukemia Using Gene Ontology Term and Kyoto Encyclopedia of Genes and Genomes Pathway Enrichment Scores
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2020, 卷号: 23, 期号: 4, 页码: 295-303
作者:
Lu, Jing
;
Zhang, YuHang
;
Wang, ShaoPeng
;
Bi, Yi
;
Huang, Tao
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  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
Leukemia
protein-drug interactions
GO term
KEGG pathway
enrichment score
mRMR
Quantitative proteomics analysis of the treatment of asthma rats with total flavonoid extract from chamomile
期刊论文
BIOTECHNOLOGY LETTERS, 2020, 卷号: 42, 期号: 6, 页码: 905-916
作者:
Li, Q (Li, Qian)[ 1,2,3 ]
;
Zhao, SJ (Zhao, Shengjun)[ 2 ]
;
Lu, J (Lu, Jun)[ 2 ]
;
Kang, XL (Kang, Xiaolong)[ 2 ]
;
Zhang, G (Zhang, Gang)[ 2 ]
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/05/27
Asthma
Chamomile
Differential expressed proteins
KIF3A
Hedgehog signaling pathway
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling
期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 14
作者:
Zhu, Rongxuan
;
Gires, Olivier
;
Zhu, Liqun
;
Liu, Jun
;
Li, Junjian
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Signaling pathway inhibitors target breast cancer stem cells in triple-negative breast cancer
期刊论文
ONCOLOGY REPORTS, 2019, 卷号: 41, 期号: 1
作者:
Xu, Ning
;
Li, Wenlong
;
Yang, Hongmei
;
Li, Xiaoli
;
Han, Lou
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/05
TNBC
BCSCs
signaling pathway inhibitors
ALDH1
Notch
Hedgehog
JAK
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