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CORC

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BRD4 Targets the KEAP1-Nrf2-G6PD Axis and Suppresses Redox Metabolism in Small Cell Lung Cancer 期刊论文
ANTIOXIDANTS, 2022, 卷号: 11
作者:  Lv, Yang;  Lv, Xiaotong;  Zhang, Jiahui;  Cao, Guozhen;  Xu, Changzhi
收藏  |  浏览/下载：27/0  |  提交时间：2022/05/16
Evaluation of JQ1 Combined With Docetaxel for the Treatment of Prostate Cancer Cells in 2D-and 3D-Culture Systems 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:  Xu, Yipeng;  Pachnikova, Gabriela;  Przybilla, Dorothea;  Schafer, Reinhold;  Cui, Yingying
收藏  |  浏览/下载：44/0  |  提交时间：2022/03/28
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载：28/0  |  提交时间：2021/12/16
Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution 期刊论文
CELL REPORTS, 2021, 卷号: 36, 期号: 4, 页码: 22
作者:  Gao, Mengqing;  Wang, Jin;  Rousseaux, Sophie;  Tan, Minjia;  Pan, Lulu
收藏  |  浏览/下载：63/0  |  提交时间：2021/11/04
Further new nardosinane-type sesquiterpenoids from the Xisha soft coral Litophyton nigrum 期刊论文
FITOTERAPIA, 2021, 卷号: 151, 页码: 4
作者:  Yang, Fan;  Hua, Qiang;  Yao, Li-Gong;  Liang, Lin-Fu;  Lu, Yan-Hua
收藏  |  浏览/下载：18/0  |  提交时间：2021/08/17
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:  Liu, Xiaohua;  Zhang, Yu;  Li, Yalei;  Wang, Juan;  Ding, Huaqian
收藏  |  浏览/下载：29/0  |  提交时间：2021/05/24
Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 20
作者:  Chen, Jingjing;  Li, Yalei;  Zhang, Jie;  Zhang, Minmin;  Wei, Aihuan
收藏  |  浏览/下载：25/0  |  提交时间：2021/05/24
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan
收藏  |  浏览/下载：20/0  |  提交时间：2021/05/24
Rational Design and Evaluation of 6-(Pyrimidin-2-ylamino)-3,4-dihydroquinoxalin-2(1H)-ones as Polypharmacological Inhibitors of BET and Kinases 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 17, 页码: 9787-9802
作者:  Lv, Kaikai;  Chen, Weicong;  Chen, Danqi;  Mou, Jie;  Zhang, Huijie
收藏  |  浏览/下载：12/0  |  提交时间：2020/12/21
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan
收藏  |  浏览/下载：23/0  |  提交时间：2020/12/24

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