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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang
收藏  |  浏览/下载:62/0  |  提交时间:2022/01/18
Nano-selenium attenuates mitochondrial-associated apoptosis via the PI3K/AKT pathway in nickel-induced hepatotoxicity in vivo and in vitro 期刊论文
ENVIRONMENTAL TOXICOLOGY, 2021
作者:  Wang, Caixia;  Gu, Zhangyu;  Gu, Xueyan;  Tan, Xinyue;  Wang, Shuang
收藏  |  浏览/下载:55/0  |  提交时间:2021/11/01
Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 43, 页码: 13
作者:  Tang, Xuehang;  Ning, Mengmeng;  Ye, Yangliang;  Gu, Yipei;  Yan, Hongyi
收藏  |  浏览/下载:49/0  |  提交时间:2021/11/04
Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2021, 页码: 20
作者:  Liu, Chenglong;  Zhou, Feilong;  Yan, Ziqin;  Shen, Lian;  Zhang, Xichen
收藏  |  浏览/下载:26/0  |  提交时间:2021/06/11
Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 37, 页码: 16
作者:  Yang, Gui-Xiang;  Sun, Jia-Min;  Zheng, Lu-Lu;  Zhang, Li;  Li, Jie
收藏  |  浏览/下载:70/0  |  提交时间:2021/06/11
In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues 期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 卷号: 65, 期号: 2, 页码: 11
作者:  Uche, Fidelia Ijeoma;  Guo, Xiaozhen;  Okokon, Jude;  Ullah, Imran;  Horrocks, Paul
收藏  |  浏览/下载:25/0  |  提交时间:2021/05/24
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Dai, Meng-di;  Wang, Yue-liang;  Fan, Jun;  Dai, Yang;  Ji, Yin-chun
收藏  |  浏览/下载:33/0  |  提交时间:2021/05/24
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju
收藏  |  浏览/下载:136/0  |  提交时间:2020/09/29
The triterpenoid sapogenin (2 alpha-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling 期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 9, 页码: 10
作者:  Xie, Zhifu;  Jiang, Haowen;  Liu, Wei;  Zhang, Xinwen;  Chen, Dakai
收藏  |  浏览/下载:32/0  |  提交时间:2020/12/21
Enhanced oral bioavailability and bioefficacy of phloretin using mixed polymeric modified self-nanoemulsions 期刊论文
FOOD SCIENCE & NUTRITION, 2020, 页码: 14
作者:  Wang, Yiling;  Li, Dongli;  Lin, Huiqiong;  Jiang, Sen;  Han, Lei
收藏  |  浏览/下载:138/0  |  提交时间:2020/07/01


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