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科研机构
上海药物研究所 [47]
内容类型
期刊论文 [47]
发表日期
2021 [47]
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发表日期:2021
专题:上海药物研究所
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Remodeling immune microenvironment in periodontitis using resveratrol liposomes as an antibiotic-free therapeutic strategy
期刊论文
Journal of Nanobiotechnology, 2021, 卷号: 19, 期号: 1
作者:
Shi,Junyu
;
Zhang,Yi
;
Zhang,Xiaomeng
;
Chen,Ruiying
;
Wei,Jianxu
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/01/04
Resveratrol
Macrophage
Periodontitis
Liposome
Immune microenvironment
Local delivery
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14
作者:
Zhang, Chun
;
Sun, Yi-Tao
;
Gao, Li-Xin
;
Feng, Bo
;
Yan, Xue
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/01/18
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Dong, Ying
;
Tang, Bi-xi
;
Wang, Qi
;
Zhou, Li-wei
;
Li, Cong
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2022/01/04
idiopathic pulmonary fibrosis
DDRs
kinase inhibitor
indazole derivatives
XBLJ-13
nintedanib
bleomycin-induced pulmonary fibrosismouse model
Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGF beta signaling
期刊论文
ONCOGENE, 2021, 页码: 10
作者:
Kong, Ya
;
Zhang, Yutian
;
Wang, Hanlin
;
Kan, Weijuan
;
Guo, Haoran
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2022/01/04
SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 339, 页码: 297-306
作者:
Huang, Ying
;
Wang, Lei
;
Cheng, Zhiyang
;
Yang, Biyu
;
Yu, Jiahui
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/12/01
Antitumour
Chemotherapy
SN38
Drug delivery systems
Albumin
Structural characteristics of Heparan sulfate required for the binding with the virus processing Enzyme Furin
期刊论文
GLYCOCONJUGATE JOURNAL, 2021, 页码: 11
作者:
Zeng, Jiaxin
;
Meng, Yuan
;
Chen, Shi-Yi
;
Zhao, Gaofeng
;
Wang, Lianchun
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2021/12/01
Furin
Heparan sulfate
Heparin
Virus infection
Carbohydrate-protein interaction
Discovery of a Potential Liver Fibrosis Inhibitor from a Mushroom Endophytic Fungus by Genome Mining of a Silent Biosynthetic Gene Cluster
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 38, 页码: 11303-11310
作者:
Cheng, Jin-Tao
;
Wang, Han-Min
;
Yu, Jia-Hui
;
Sun, Chen-Fan
;
Cao, Fei
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/12/01
fungus
Calcarisporium arbuscula
natural product
gene cluster activation
liver fibrosis
Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain
期刊论文
MOLECULAR BRAIN, 2021, 卷号: 14, 期号: 1, 页码: 22
作者:
Shao, Fang-bing
;
Fang, Jun-fan
;
Wang, Si-si
;
Qiu, Meng-ting
;
Xi, Dan-ning
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2021/11/04
Chronic inflammatory pain
Anxiety-like behavior
GABAergic system
Anterior cingulate cortex
synaptic transmission
Forrestiacids A and B, Pentaterpene Inhibitors of ACL and Lipogenesis: Extending the Limits of Computational NMR Methods in the Structure Assignment of Complex Natural Products
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 7
作者:
Xiong, Juan
;
Zhou, Peng-Jun
;
Jiang, Hao-Wen
;
Huang, Ting
;
He, Yu-Hang
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2021/11/04
forrestiacids
lipogenesis inhibitors
natural products
structure elucidation
terpenoids
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