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科研机构
上海药物研究所 [5]
南华大学 [1]
北京大学 [1]
中国科学院大学 [1]
内容类型
期刊论文 [8]
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2021 [2]
2019 [1]
2016 [1]
2015 [1]
2014 [1]
2012 [1]
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Forrestiacids A and B, Pentaterpene Inhibitors of ACL and Lipogenesis: Extending the Limits of Computational NMR Methods in the Structure Assignment of Complex Natural Products
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 7
作者:
Xiong, Juan
;
Zhou, Peng-Jun
;
Jiang, Hao-Wen
;
Huang, Ting
;
He, Yu-Hang
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/11/04
forrestiacids
lipogenesis inhibitors
natural products
structure elucidation
terpenoids
S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis
期刊论文
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2021, 卷号: 11, 期号: 3, 页码: 697-724
作者:
Zhang, Linqiang
;
Zhang, Zhiguo
;
Li, Chengbin
;
Zhu, Tingting
;
Gao, Jing
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/05/24
NAFLD
S100A11
FOXO1
Autophagy
Lipid Metabolism
Inhibition of HSP90 beta Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System
期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 20, 页码: 5769-5783
作者:
Zheng, Zu-Guo
;
Zhang, Xin
;
Liu, Xiao-Xiao
;
Jin, Xiu-Xiu
;
Dai, Lunzhi
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
HSP90 beta
lipid metabolism
corylin
SREBPs
proteasomal degradation
Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 67071-67086
作者:
Qian, Jianchang
;
Chen, Yaqing
;
Meng, Tao
;
Ma, Lanping
;
Meng, Lanfang
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
mTOR kinase inhibitor
mTORC2
apoptosis
lipid metabolism
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling
期刊论文
NATURE CELL BIOLOGY, 2015
Lin, Ruiting
;
Elf, Shannon
;
Shan, Changliang
;
Kang, Hee-Bum
;
Ji, Quanjiang
;
Zhou, Lu
;
Hitosugi, Taro
;
Zhang, Liang
;
Zhang, Shuai
;
Seo, Jae Ho
;
Xie, Jianxin
;
Tucker, Meghan
;
Gu, Ting-Lei
;
Sudderth, Jessica
;
Jiang, Lei
;
Mitsche, Matthew
;
DeBerardinis, Ralph J.
;
Wu, Shaoxiong
;
Li, Yuancheng
;
Mao, Hui
;
Chen, Peng R.
;
Wang, Dongsheng
;
Chen, Georgia Zhuo
;
Hurwitz, Selwyn J.
;
Lonial, Sagar
;
Arellano, Martha L.
;
Khoury, Hanna J.
;
Khuri, Fadlo R.
;
Lee, Benjamin H.
;
Lei, Qunying
;
Brat, Daniel J.
;
Ye, Keqiang
;
Boggon, Titus J.
;
He, Chuan
;
Kang, Sumin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
ACETYL-COA CARBOXYLASE
ACTIVATED PROTEIN-KINASE
PHOSPHORYLATION SITES
GLUCOSE-6-PHOSPHATE-DEHYDROGENASE ACTIVITY
CELL METABOLISM
ENERGY STRESS
CANCER-CELLS
FATTY-ACID
IN-SITU
LKB1
Azoxystrobin, a mitochondrial complex III Q(o) site inhibitor, exerts beneficial metabolic effects in vivo and in vitro
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2014, 卷号: 1840, 期号: 7, 页码: 2212-2221
作者:
Gao, An-Hui
;
Fu, Yan-Yun
;
Zhang, Kun-Zhi
;
Zhang, Mei
;
Jiang, Hao-Wen
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Azoxystrobin
Mitochondria complex III
Metabolic diseases
AMP-activated protein kinase
ATP Citrate Lyase Inhibitors as Novel Cancer Therapeutic Agents
期刊论文
Recent Patents on Anti-Cancer Drug Discovery, 2012, 卷号: 7, 期号: 2, 页码: 154-167
作者:
Zu, Xu-Yu
;
Zhang, Qing-Hai
;
Liu, Jiang-Hua
;
Cao, Ren-Xian
;
Zhong, Jing
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/27
ACL inhibitors
ATP citrate lyase
Hydroxycitrate
Non-hydroxycitrate Citric Acid Analogues
Posttranslational regulation
Transcriptional regulation
cancer therapy
citrate
lipogenesis
small chemicals
Evaluation of the inhibitory activities of aceraceous plants on fatty acid synthase
期刊论文
Journal of enzyme inhibition and medicinal chemistry, 2007, 卷号: 22, 期号: 4, 页码: 501-510
作者:
Zhao, Wen-Hua
;
Gao, Chunchun
;
Zhang, Ying-Xia
;
Tian, Wei-Xi
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/05/10
Fatty acid synthase
Enzyme inhibition
Antitumor
Aceraceae
Kinetics
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