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科研机构
上海药物研究所 [64]
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期刊论文 [63]
会议论文 [1]
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2021 [2]
2019 [3]
2017 [4]
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Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:
Zhou, Yu
;
Li, Xiaoguang
;
Chen, Kerong
;
Ba, Qian
;
Zhang, Xu
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/06/11
Structural optimization
Lead compound
Artemisinin derivatives
Cancer
Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:
Zhou, Yu
;
Li, Xiaoguang
;
Chen, Kerong
;
Ba, Qian
;
Zhang, Xu
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/24
Structural optimization
Lead compound
Artemisinin derivatives
Cancer
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yang, Fang-ming
;
Fan, Di
;
Yang, Xiao-qian
;
Zhu, Feng-hua
;
Shao, Mei-juan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
dry eye disease
artemisinin derivative
beta-aminoarteether maleate
inflammation
macrophages
TLR4
inflammasome
Novel dihydroartemisinin dimer containing nitrogen atoms inhibits growth of endometrial cancer cells and may correlate with increasing intracellular peroxynitrite
期刊论文
SCIENTIFIC REPORTS, 2019, 卷号: 9, 页码: 14
作者:
Zhu, Yan
;
Klausen, Christian
;
Zhou, Jieyun
;
Guo, Xiangjie
;
Zhang, Yu
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2020/07/01
Quantitative Analysis of Artemisinin Derivatives: Applications and Techniques
期刊论文
SEPARATION AND PURIFICATION REVIEWS, 2019, 卷号: 48, 期号: 3, 页码: 242-266
作者:
Zhang, Lili
;
Jiang, Yanyan
;
Li, Ning
;
Pu, Yiqiong
;
Zhang, Tong
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
Artemisinin derivatives
quantitative analysis
spectroscopy
chromatography
mass spectrometry
Biological Activities of Artemisinin Derivatives Beyond Malaria
期刊论文
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2019, 卷号: 19, 期号: 3, 页码: 205-222
作者:
Liu, Xiaoyan
;
Cao, Jianguo
;
Huang, Guozheng
;
Zhao, Qingjie
;
Shen, Jingshan
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
Anticancer activity
Antiviral activity
Artemisinin
Artemisinin derivatives
Dimer
Trimer
Development of high potent and selective Bcl-2 inhibitors bearing the structural elements of natural product artemisinin
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 159, 页码: 149-165
作者:
Liu, Xiaohua
;
Zhang, Yu
;
Huang, Wenjing
;
Luo, Jia
;
Li, Yang
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  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Apoptosis
Artemisinin
Bcl-2
Venetoclax
Selectivity
Dihydroartemisinin selectively inhibits PDGFR alpha-positive ovarian cancer growth and metastasis through inducing degradation of PDGFR alpha protein
期刊论文
CELL DISCOVERY, 2017, 卷号: 3
作者:
Li, Xiaoguang
;
Ba, Qian
;
Liu, Yanling
;
Yue, Qingxi
;
Chen, Peizhan
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
Dihydroartemisinin
Epithelial-mesenchymal transition
metastasis
ovarian cancer
PDGFR alpha
Water-soluble artemisinin derivatives as promising therapeutic immunosuppressants of autoimmune diseases
期刊论文
CELLULAR & MOLECULAR IMMUNOLOGY, 2017, 卷号: 14, 期号: 11, 页码: 887-889
作者:
Li, Heng
;
Zuo, Jianping
;
Tang, Wei
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08
Incorporation of Dihydroartemisinin into Memantine Through a Propriate Spacer to Make Hybrid with Enhanced Effects to Protect PC12 Cells from Corticosterone-caused Impairments
期刊论文
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 卷号: 33, 期号: 4, 页码: 611-622
作者:
Zhang Lei
;
Zhou Fan
;
Zhang Laitao
;
Peng Lizhi
;
Guo Cuiping
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Artemisinin
Memantine
Neuroprotection
N-Methyl-D-aspartate(NMDA) receptor
Depression
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