Biological Activities of Artemisinin Derivatives Beyond Malaria

doi:10.2174/1568026619666190122144217

	Biological Activities of Artemisinin Derivatives Beyond Malaria
	Liu, Xiaoyan 1,3; Cao, Jianguo 3; Huang, Guozheng 2,3; Zhao, Qingjie 1; Shen, Jingshan 1
刊名	CURRENT TOPICS IN MEDICINAL CHEMISTRY
	2019
卷号	19 期号:3 页码:205-222
关键词	Anticancer activity Antiviral activity Artemisinin Artemisinin derivatives Dimer Trimer
ISSN号	1568-0266
DOI	10.2174/1568026619666190122144217
通讯作者	Huang, Guozheng(g.huang@ms.xjb.ac.cn) ; Zhao, Qingjie(zhaoqingjie@simm.ac.cn)
英文摘要	Artemisinin is isolated from Artemisia annua L. with peroxide-containing sesquiterpene lactone structure. Because of its unique structural characteristics and promising anticancer, antivirus activities, it has recently received increasing attention. The aim of this review is to summarize recent discoveries of artemisinin's novel derivatives with new pharmaceutical effects beyond malaria with a focus on its antitumor and antivirus activity, as well as potential results of combination therapy with other clinical drugs.
资助项目	Shanghai Pujiang Program[16PJ1410700] ; Institutes for Drug Discovery and Development, Chinese Academy of Sciences[CASIMM0120164019] ; Personalized Medicines-Molecular Signature-based Drug Discovery and Development, Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12040322]
WOS关键词	TRADITIONAL CHINESE MEDICINE ; CELL-CYCLE ARREST ; PLASMODIUM-FALCIPARUM ; IN-VITRO ; HUMAN CYTOMEGALOVIRUS ; NATURAL-PRODUCTS ; CANCER-CELLS ; ANTICANCER ACTIVITY ; ANTIVIRAL ACTIVITY ; ANTITUMOR-ACTIVITY
WOS研究方向	Pharmacology & Pharmacy
语种	英语
出版者	BENTHAM SCIENCE PUBL LTD
WOS记录号	WOS:000464102200006
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/289982]
专题	中国科学院上海药物研究所
通讯作者	Huang, Guozheng; Zhao, Qingjie
作者单位	1.Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, Shanghai 201203, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Urumqi 830011, Peoples R China 3.Shanghai Normal Univ, Coll Life & Environm Sci, Shanghai 201418, Peoples R China
推荐引用方式 GB/T 7714	Liu, Xiaoyan,Cao, Jianguo,Huang, Guozheng,et al. Biological Activities of Artemisinin Derivatives Beyond Malaria[J]. CURRENT TOPICS IN MEDICINAL CHEMISTRY,2019,19(3):205-222.
APA	Liu, Xiaoyan,Cao, Jianguo,Huang, Guozheng,Zhao, Qingjie,&Shen, Jingshan.(2019).Biological Activities of Artemisinin Derivatives Beyond Malaria.CURRENT TOPICS IN MEDICINAL CHEMISTRY,19(3),205-222.
MLA	Liu, Xiaoyan,et al."Biological Activities of Artemisinin Derivatives Beyond Malaria".CURRENT TOPICS IN MEDICINAL CHEMISTRY 19.3(2019):205-222.