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上海药物研究所 [13]
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兰州大学 [4]
复旦大学上海医学院 [4]
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期刊论文 [50]
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Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11
作者:
Fan, Shijie
;
Yue, Liyan
;
Wan, Wei
;
Zhang, Yuanyuan
;
Zhang, Bidong
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2021/12/16
covalent modification
probes
proteome
LC3
post-translational modification
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion
期刊论文
ADVANCED SCIENCE, 2020, 页码: 13
作者:
Sun, Zhongya
;
Zhang, Hao
;
Zhang, Yuanyuan
;
Liao, Liping
;
Zhou, Wen
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  |  
浏览/下载:105/0
  |  
提交时间:2020/07/01
anti-metastasis activities
crystal structures
inhibitors
novel pockets
rho family proteins
Petrogenesis of volcanic rocks from Eastern Manus Basin: indications in mineralogy and geochemistry
期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 页码: 21
作者:
Zhao Xia
;
Tian Liyan
;
Sun Jianhui
;
Huang Peng
;
Li Yan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/10/26
Eastern Manus Basin
plagioclase
pyroxene
whole rock
Sr-Nd-Pb isotope
magma
Petrogenesis of volcanic rocks from Eastern Manus Basin: indications in mineralogy and geochemistry
期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 页码: 21
作者:
Zhao Xia
;
Tian Liyan
;
Sun Jianhui
;
Huang Peng
;
Li Yan
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/11/02
Eastern Manus Basin
plagioclase
pyroxene
whole rock
Sr-Nd-Pb isotope
magma
A ratiometric fluorescent probe for detecting the endogenous biological signaling molecule superoxide anion and bioimaging during tumor treatment
期刊论文
JOURNAL OF MATERIALS CHEMISTRY B, 2020, 卷号: 8, 期号: 5, 页码: 1017-1025
作者:
Wang, Yue
;
Wang, Xiaoyan
;
Zhang, Li
;
Huang, Yan
;
Bi, Liyan
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  |  
浏览/下载:36/0
  |  
提交时间:2020/07/08
CISPLATIN-INDUCED NEPHROTOXICITY
REACTIVE OXYGEN
VITAMIN-C
CELL-PROLIFERATION
LIPID-PEROXIDATION
OXIDATIVE STRESS
CURCUMIN
MECHANISMS
MITOCHONDRIA
INHIBITION
discoveryofnovelcbpbromodomaininhibitorsthroughtrfretbasedhighthroughputscreening
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 285
作者:
Zhang Fengcai
;
Sun Zhongya
;
Liao Liping
;
Zuo Yu
;
Zhang Dan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:
Lu, Wenchao
;
Wang, Jun
;
Li, Yong
;
Tao, Hongru
;
Xiong, Huan
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2020/07/01
Hippo pathway
TEAD transcription factor
Covalent inhibitor
Palmitoylation inhibitor
Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening
期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 9, 页码: 4917-4924
作者:
Tao, Hongru
;
Wang, Jun
;
Lu, Wenchao
;
Zhang, Rukang
;
Xie, Yiqian
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Loss of hypermethylated in cancer 1 (HIC1) promotes lung cancer progression
期刊论文
CELLULAR SIGNALLING, 2019, 卷号: 53
作者:
Li, Yue
;
Yao, Mengfei
;
Wu, Tianqi
;
Zhang, Liyan
;
Wang, Yingying
收藏
  |  
浏览/下载:124/0
  |  
提交时间:2019/12/05
HIC1
Lung cancer
DNA repair pathway
Tumorigenesis
Cytomegalovirus Infection May Trigger Adult-Onset Still's Disease Onset or Relapses
期刊论文
FRONTIERS IN IMMUNOLOGY, 2019, 卷号: 10
作者:
Jia, Jinchao
;
Shi, Hui
;
Liu, Mengguo
;
Liu, Tingting
;
Gu, Jieyu
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/12/05
adult-onset Still's disease
virus
CMV
IFI16
AIM2
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