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科研机构
大连理工大学 [10]
上海药物研究所 [5]
山东大学 [5]
上海健康医学院 [4]
山东师范大学 [2]
复旦大学上海医学院 [2]
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期刊论文 [34]
会议论文 [1]
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2020 [4]
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Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5
作者:
Zhang, Bin
;
Liao, Liping
;
Wu, Fan
;
Zhang, Fengcai
;
Sun, Zhongya
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/05/24
SMYD2 inhibitors
Thermal shift assay
Structure-activity relationships
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion
期刊论文
ADVANCED SCIENCE, 2020, 页码: 13
作者:
Sun, Zhongya
;
Zhang, Hao
;
Zhang, Yuanyuan
;
Liao, Liping
;
Zhou, Wen
收藏
  |  
浏览/下载:105/0
  |  
提交时间:2020/07/01
anti-metastasis activities
crystal structures
inhibitors
novel pockets
rho family proteins
discoveryofnovelcbpbromodomaininhibitorsthroughtrfretbasedhighthroughputscreening
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 285
作者:
Zhang Fengcai
;
Sun Zhongya
;
Liao Liping
;
Zuo Yu
;
Zhang Dan
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  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 86, 页码: 494-500
作者:
Zhang, Dan
;
Han, Jie
;
Lu, Wenchao
;
Lian, Fulin
;
Wang, Jun
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Lysine acetylation
Bromodomain
Virtual screening
BPTF inhibitor
Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening
期刊论文
Bioorganic chemistry, 2019, 卷号: 86, 页码: 494-500
作者:
Zhang Dan[1]
;
Han Jie[2]
;
Lu Wenchao[3]
;
Lian Fulin[4]
;
Wang Jun[5]
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/04/22
BPTF inhibitor
Bromodomain
Lysine acetylation
Virtual screening
Effect of maternal antibody on the infant immune response to inactivated poliovirus vaccines made from Sabin strains.
期刊论文
Human vaccines & immunotherapeutics, 2019
作者:
Rong Tang
;
Kai Chu
;
Yuansheng Hu
;
Lei Chen
;
Ming Zhang
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  |  
浏览/下载:3/0
  |  
提交时间:2019/12/13
Inactivated
poliovirus
vaccine
Maternal
antibody
Sabin
strains
immune
response
inactivated
poliovirus
vaccine
Research on the Path Mechanism and Reconstruction Mode of the Combination of Sports and Related Industries
会议论文
International Conference on Arts, Management, Education and Innovation (ICAMEI), JAN 12-14, 2019
作者:
Chen Fengcai
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  |  
浏览/下载:3/0
  |  
提交时间:2019/12/31
Sports industry
industry integration
development
path
OCCURRENCE AND GENETIC CHARACTERIZATION OF GRA6 AND SAG2 FROM TOXOPLASMA GONDII OOCYSTS IN CAT FECES, KUNMING, CHINA
期刊论文
SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH, 2017, 卷号: 47, 期号: 6, 页码: 1134-1142
Liang, Yu
;
Chen, JinQing
;
Meng, Yu
;
Zou, FengCai
;
Hu, JunJie
;
Esch, G. W.
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2017/03/10
Toxoplasma gondii
cat
fecal oocyst
genetic characterization
Coupling effect on charge-transfer mechanism of surface-enhanced resonance Raman scattering
期刊论文
JOURNAL OF RAMAN SPECTROSCOPY, 2017, 卷号: 48, 页码: 560-569
作者:
Li, Quanjiang
;
Wang, Jingang
;
Ding, Qianqian
;
Chen, Maodu
;
Ma, Fengcai
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/02
coupling effect
charge transfer
SERRS
DFT
Ac@Au-7 cluster
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