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中南大学 [8]
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期刊论文 [8]
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2018 [1]
2017 [2]
2016 [1]
2014 [2]
2013 [1]
2010 [1]
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Metabolomics-based evidence of the hypoglycemic effect of Ge-Gen-Jiao-Tai-Wan in type 2 diabetic rats via UHPLC-QTOF/MS analysis
期刊论文
Journal of Ethnopharmacology, 2018, 卷号: 219, 页码: 299-318
作者:
Wang, Wenbo
;
Zhao, Linlin
;
He, Zhenyu
;
Wu, Ning
;
Li, Qiuxia
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/03
GGJTW
Ge-Gen-Jiao-Tai-Wan
T2DM
type 2 diabetes mellitus
TCMs
traditional Chinese medicines
UHPLC-QTOF/MS
ultra high performance liquid chromatography coupled with quadrupole-time-of-flight tandem mass spectrometry
BAs
bile acids
Ge-Gen-Jiao-Tai-Wan
Type 2 diabetes
Metabolomics
UHPLC-QTOF/MS
Therapeutic effects
Chinese herbal medicine
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
Serum TNF-α concentrations in type 2 diabetes mellitus patients and diabetic nephropathy patients: A systematic review and meta-analysis
期刊论文
Immunology Letters, 2017, 卷号: 186, 页码: 52-58
作者:
Chen, Yin-ling
;
Qiao, Yong-chao
;
Xu, Yan
;
Ling, Wei
;
Pan, Yan-hong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
TNF-α
tumor necrosis factor-α
T2DM
type 2 diabetes mellitus
T2DN
type 2 diabetic nephropathy
Tumor necrosis factor-α
Type 2 diabetes mellitus
Diabetic nephropathy
Albuminuria
Meta-analyses
Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells
期刊论文
Cellular Signalling, 2016, 卷号: 28, 期号: 8, 页码: 1099-1104
作者:
Wang, Jing
;
Yang, Xin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/03
4E-BP1
4E binding protein
AMPK
AMP-activated protein kinase
ATF6
activating transcription factor 6
ATP
adenosine triphosphate
DEPTOR
DEP domain containing mTOR-interacting protein
CI
complexes I
CII
complex II
CIII
complex III
CIV
complex IV
CV
complex V
eIF2α
Eukaryotic Initiation Factor 2α
ER
Endoplasmic Reticulum
ERAD
ER-associated degradation
ERO1α
ER oxidoreductase 1 α
FoxO1
Forkhead box O1
GβL
G Protein β Subunit Like Protein
GRP78
78 kDa glucose-regulated protein precursor
GSIS
glucose-stimulated insulin secretion
IRE1
Inositol-requiring enzyme 1
IRS1
Insulin receptor substrate 1
IRS2
Insulin receptor substrate 2
mLST8
mammalian lethal with sec-13 protein 8
mSin1
the mammalian stress-activated MAP kinase-interaction protein 1
mtDNA
mitochondrial deoxyribonucleic acid
mTOR
mammalian TOR
mTORC1
mTOR complex 1
mTORC2
mTOR complex 2
NADPH oxidase
Nicotinamide adenine dinucleotide phosphate-oxidase
NOS
nitric oxide synthase
O2–·
superoxide anion
H2O2
hydrogen peroxide
OH·
hydroxyl radical
3O2
triplet-state molecular oxygen
OXPHOS
oxidative phosphorylation
CAT
catalase
GPx
glutathioneperoxidase
PERK
Protein kinase R-like endoplasmic reticulum kinase
PDI
ER protein disulfide isomerases
PI3K
the phosphoinositide3-kinase
PRAS40
40-kDa proline-rich Akt substrate
PRAS40
the 40-kDa proline-rich Akt substrate
PROTOR
the protein observed with RICTOR
RAPTOR
regulatory-associated protein of mTOR
RICTOR
The rapamycin-insensitive companion of mTOR
REDD1
DNA damage response 1
RNS
reactive nitrogen species
ROS
reactive oxygen species
RNS
reactive nitrogen species
S6K
S6 kinase
SOD
superoxidedismutase
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TOR
the target of rapamycin
TSC2
Tuberous sclerosis 2
UPR
unfolded protein response
Mitochondrial oxidative stress
ER stress
mTOR
Pancreatic β cells
Exploring metabolic syndrome serum profiling based on gas chromatography mass spectrometry and random forest models
期刊论文
Analytica Chimica Acta, 2014, 卷号: 827, 页码: 22-27
作者:
Lin, Zhang
;
Vicente Gonç
;
alves, Carlos M.
;
Dai, Ling
;
Lu, Hong-mei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/03
RF
Random forests
MetS
Metabolic syndrome
GC–MS
Gas chromatography–mass spectrometry
UPLC-QTOF-MS
Ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry
1H NMR
1H Nuclear magnetic resonance
HDL-C
High density lipoprotein-cholesterol
WHO
World Health Organization
NCEP
Nation Cholesterol Education Panel
IDF
International Diabetes Federation
BMI
Body mass index
SBP/DBP
Systolic blood pressure/diastolic blood pressure
TG
Triglyceride
CDS
The Chinese diabetes society
T2DM
Type 2 diabetes mellitus
CVD
Cardio vascular disorder
QC
Quality control
Metabolic syndrome
Serum profiling
GC–MS
Random forest
Biomarker
Lixisenatide treatment improves glycaemic control in Asian patients with type 2 diabetes mellitus inadequately controlled on metformin with or without sulfonylurea: a randomized, double‐blind, placebo‐controlled, 24‐week trial (GetGoal‐M‐Asia)
期刊论文
Diabetes/Metabolism Research and Reviews, 2014, 卷号: 30, 期号: 8, 页码: 726-735
作者:
Pan, Chang Yu*
;
Han, Ping
;
Liu, Xiaoming
;
Yan, Shengli
;
Feng, Ping
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/03
lixisenatide
type 2 diabetes mellitus (T2DM)
glucagon‐like peptide‐1 (GLP‐1) receptor agonists
Asia
Exploring the relationship between 5′AMP-activated protein kinase and markers related to type 2 diabetes mellitus
期刊论文
Talanta, 2013, 卷号: 110, 页码: 1-7
作者:
Huang, Jian-Hua
;
He, Rui-Hua
;
Yi, Lun-Zhao
;
Xie, Hua-Lin
;
Cao, Dong-sheng
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/03
5′AMP-activated protein kinase
AMPK
Type II diabetes mellitus
T2DM
Adenosine tri-phosphate
ATP
Random forest
RF
Multidimensional scaling
MDS
5′AMP-activated protein kinase (AMPK)
Metabolites
Random forest
GC/MS
Gender variation
Identification of free fatty acids profiling of type 2 diabetes mellitus and exploring possible biomarkers by GC-MS coupled with chemometrics
期刊论文
Metabolomics, 2010, 卷号: 6, 期号: 2, 页码: 219-228
作者:
Binbin Tan
;
Yizeng Liang
;
Lunzhao Yi
;
Hongdong Li
;
Zhiguang Zhou
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
Biomarkers
Competitive adaptive reweighted sampling (CARS)
Free fatty acids (FFAs)
Heuristic evolving latent projections (HELP)
Selective ion analysis (SIA)
Type 2 diabetes mellitus (T2DM)
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