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CORC

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Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists 期刊论文
PHARMACEUTICALS, 2022, 卷号: 15
作者:  Sun, Lei;  Zheng, Zhi-Ming;  Shao, Chang-Sheng;  Zhang, Zhi-Yong;  Li, Ming-Wei
收藏  |  浏览/下载：15/0  |  提交时间：2022/12/22
Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452
作者:  Wang, Jiang;  Yang, Dehua;  Cheng, Xi;  Yang, Linlin;  Wang, Zhaohui
收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04
Signaling profiles in HEK 293T cells co-expressing GLP-1 and GIP receptors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 8
作者:  Wang, Yu-zhe;  Yang, De-hua;  Wang, Ming-wei
收藏  |  浏览/下载：18/0  |  提交时间：2021/11/04
Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14
作者:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton
收藏  |  浏览/下载：39/0  |  提交时间：2021/08/17
Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:  Cong, Zhaotong;  Chen, Li-Nan;  Ma, Honglei;  Zhou, Qingtong;  Zou, Xinyu
收藏  |  浏览/下载：43/0  |  提交时间：2021/08/17
G protein-coupled receptors: structure- and function-based drug discovery 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 27
作者:  Yang, Dehua;  Zhou, Qingtong;  Labroska, Viktorija;  Qin, Shanshan;  Darbalaei, Sanaz
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor 期刊论文
CELL RESEARCH, 2020, 页码: 11
作者:  Sun, Wen;  Chen, Li-Nan;  Zhou, Qingtong;  Zhao, Li-Hua;  Yang, Dehua
收藏  |  浏览/下载：84/0  |  提交时间：2020/12/24
Design of G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) soft drugs with reduced gallbladder-filling effects 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 12
作者:  Han, Fanghui;  Ning, Mengmeng;  Cao, Hua;  Ye, Yangliang;  Feng, Ying
收藏  |  浏览/下载：32/0  |  提交时间：2020/12/21
Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 180, 页码: 16
作者:  Darbalaei, Sanaz;  Yuliantie, Elita;  Dai, Antao;  Chang, Rulue;  Zhao, Peishen
收藏  |  浏览/下载：18/0  |  提交时间：2020/12/21
The triterpenoid sapogenin (2 alpha-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling 期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 9, 页码: 10
作者:  Xie, Zhifu;  Jiang, Haowen;  Liu, Wei;  Zhang, Xinwen;  Chen, Dakai
收藏  |  浏览/下载：30/0  |  提交时间：2020/12/21

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