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科研机构
上海药物研究所 [7]
武汉岩土力学研究所 [2]
力学研究所 [1]
数学与系统科学研究院 [1]
昆明植物研究所 [1]
海洋研究所 [1]
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期刊论文 [13]
发表日期
2020 [13]
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A survey on network node ranking algorithms: Representative methods, extensions, and applications
期刊论文
SCIENCE CHINA-TECHNOLOGICAL SCIENCES, 2020, 页码: 11
作者:
Liu, JiaQi
;
Li, XueRong
;
Dong, JiChang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/01/14
complex networks
node ranking methods
PageRank
HITS
algorithms
In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2020, 卷号: 60, 期号: 6, 页码: 3265-3276
作者:
Zhao, Wenfeng
;
Xiong, Muya
;
Yuan, Xiaojing
;
Li, Minjun
;
Sun, Hongbin
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/12/24
Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5
期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 12, 页码: 18
作者:
Han, Haozhen
;
Li, Chunpu
;
Li, Man
;
Yang, Lisheng
;
Zhao, Sen
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/12/24
sirtuins
inhibitor
structure-activity relationship
deacetylase
Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:
Zhou, Yan
;
Du, Dao-Hai
;
Wang, Jia
;
Cai, Xiao-Qing
;
Deng, Alicia X.
收藏
  |  
浏览/下载:102/0
  |  
提交时间:2020/07/01
embryonic ectoderm development
Enhancer of zeste homolog 2
fluorescence polarization
high-throughput screening
homogenous time-resolved fluorescence
inhibitor
polycomb repressive complex 2
Foliation Effects on Mechanical and Failure Characteristics of Slate in 3D Space Under Brazilian Test Conditions
期刊论文
ROCK MECHANICS AND ROCK ENGINEERING, 2020, 页码: 18
作者:
Ding, Changdong
;
Zhang, Yang
;
Hu, Dawei
;
Zhou, Hui
;
Shao, Jianfu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/05/25
Anisotropic slate
Brazilian test
Foliation effects
Rock mechanics
Failure characteristics
Three-dimensional (3D) space
Longitudinal interference analysis of shale gas multi-stage fracturing horizontal wells upon high-precision pressure test
期刊论文
ENERGY SCIENCE & ENGINEERING, 2020, 页码: 15
作者:
Gao DP(高大鹏)
;
Liu YW(刘曰武)
;
Pan SQ
;
Wang J
;
Zhou XM
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/08/26
industrial application
industrial engineering
multi-stage fracturing horizontal wells
numerical analysis
pressure response analysis
shale gas
well interference
High-throughput screening campaign identifies a small molecule agonist of the relaxin family peptide receptor 4
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Lin, Guang-yao
;
Lin, Lin
;
Cai, Xiao-qing
;
Dai, An-tao
;
Zhu, Yue
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  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
RXFP4
INSL5
high-throughput screening
agonist
JK1
Asperity degradation characteristics of soft rock-like fractures under shearing based on acoustic emission monitoring
期刊论文
ENGINEERING GEOLOGY, 2020, 卷号: 266, 页码: 14
作者:
Meng, Fanzhen
;
Wong, Louis Ngai Yuen
;
Zhou, Hui
;
Wang, Zaiquan
;
Zhang, Liming
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2021/05/25
Rock fracture
Acoustic emission
Asperity degradation
Damage model
AE b-value
Discovery and characterization of natural products as novel indoleamine 2,3-dioxygenase 1 inhibitors through high-throughput screening
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 423-431
作者:
Guo, Wei
;
Yao, Sheng
;
Sun, Pu
;
Yang, Tian-biao
;
Tang, Chun-ping
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2020/07/01
indoleamine 2
3-dioxygenase 1 inhibitor
natural product library
high-throughput fluorescence-based screening
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:
Weng, Zhiying
;
Xu, Guowei
;
Chen, Dingyuan
;
Yang, Yaqing
;
Song, Gao
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/03/18
Adenylyl cyclases
Homology modeling
Consensus scoring
Molecular dynamics simulation
Virtual screening
Biological evaluation
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