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Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5 期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 12, 页码: 18
作者:  Han, Haozhen;  Li, Chunpu;  Li, Man;  Yang, Lisheng;  Zhao, Sen
收藏  |  浏览/下载:35/0  |  提交时间:2020/12/24
Molecular dynamics simulations reveal the mechanism of the interactions between the inhibitors and SIRT2 at atom level 期刊论文
MOLECULAR SIMULATION, 2020, 卷号: 46, 期号: 8, 页码: 638-649
作者:  Wang, Xiaoyu;  Song, Menghua;  Zhao, Shuang;  Li, Huiyu;  Zhao, Qingjie
收藏  |  浏览/下载:34/0  |  提交时间:2020/07/01
Structural Insight into the Interactions between Structurally Similar Inhibitors and SIRT6 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 7, 页码: 15
作者:  Zhao, Shuang;  Zhu, Yan-Yan;  Wang, Xiao-Yu;  Liu, Yong-Sheng;  Sun, Yun-Xiang
收藏  |  浏览/下载:30/0  |  提交时间:2020/07/01
Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:  Li, Man;  Li, Shi-chun;  Dou, Bao-kai;  Zou, Ying-xiang;  Han, Hao-zhen
收藏  |  浏览/下载:34/0  |  提交时间:2020/07/01
SIRT5 Regulates Brown Adipocyte Differentiation and Browning of Subcutaneous White Adipose Tissue 期刊论文
DIABETES, 2019, 卷号: 68, 期号: 7, 页码: 1449-1461
作者:  Shuai, Lin;  Zhang, Li-Na;  Li, Bo-Han;  Tang, Chun-Lan;  Wu, Ling-Yan
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/01
SIRT6/HIF-1 alpha axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition 期刊论文
CANCER CELL INTERNATIONAL, 2019, 卷号: 19
作者:  Yang, Zhou;  Yu, Weiping;  Huang, Renhong;  Ye, Min;  Min, Zhijun
收藏  |  浏览/下载:31/0  |  提交时间:2019/12/05
Sirtuins在肾脏疾病中的研究进展 期刊论文
Journal of Medical Research, 2019, 期号: 06
作者:  范燕琴;  丁国华
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/05
Effects of Mitochondrial Dysfunction via AMPK/PGC-1 alpha Signal Pathway on Pathogenic Mechanism of Diabetic Peripheral Neuropathy and the Protective Effects of Chinese Medicine 期刊论文
2019, 卷号: 25, 期号: 5, 页码: 386-394
作者:  Zhang Qian;  Liang Xiao-chun
收藏  |  浏览/下载:12/0  |  提交时间:2020/01/03
SIRT5 Promotes Hepatocellular Carcinoma Progression by Regulating Mitochondrial Apoptosis 期刊论文
JOURNAL OF CANCER, 2019, 卷号: 10, 期号: 16, 页码: 3871-3882
作者:  Zhang, Rixin;  Wang, Chengye;  Tian, Yu;  Yao, Yifan;  Mao, Jiakai
收藏  |  浏览/下载:46/0  |  提交时间:2019/12/02
Targeting NAD(+) degradation: The therapeutic potential of flavonoids for Alzheimer's disease and cognitive frailty 期刊论文
PHARMACOLOGICAL RESEARCH, 2018, 卷号: 128
作者:  Ruan, Qingwei;  Ruan, Jian;  Zhang, Weibin;  Qian, Feng;  Yu, Zhuowei
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/05


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