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Role of C/EBP homologous protein and endoplasmic reticulum stress in asthma exacerbation by regulating the IL-4/signal transducer and activator of transcription 6/transcription factor EC/IL-4 receptor α positive feedback loop in M2 macrophages 期刊论文
Journal of Allergy and Clinical Immunology, 2017, 卷号: 140, 期号: 6, 页码: 1550-1561.e8
作者:  Wang, Yi;  Zhu, Jianghui;  Zhang, Lei;  Zhang, Zhijun;  He, Long
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/03
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells 期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:  Yang, Xin;  Xu, Zhipeng;  Zhang, Chunlan;  Cai, Zixin;  Zhang, Jingjing*
收藏  |  浏览/下载:35/0  |  提交时间:2019/12/03
A1c  glycated hemoglobin  AACE  American Association of Clinical Endocrinologists  ACC  acetyl-CoA carboxylase  ADA  American Diabetes Association  Akt/PKB  tyrosine kinase/protein kinase B  AMP  adenosine monophosphate  AMPK  adenosine monophosphate-activated protein  Ang II  angiotensin II  ATP  adenosine triphosphate  BAT  brown adipose tissue  CHOP  CEBP-homologous protein  CEBP  CCAAT enhancer binding protein  CoA  coenzyme A  DPP  Diabetes Prevention Program  EASD  European Association for the Study of Diabetes  eNOS  endothelial nitric oxide synthase  ER  endoplasmic reticulum  FDA  Food and Drug Administration  FFA  free fatty acid  FOXO1  forkhead box protein O1  G6P  glucose 6-phosphate  GDM  gestational diabetes mellitus  GIPR  glucose-dependent insulinotropic polypeptide receptor  GLP-1R  glucagon-like peptide-1 receptor  GLUT1  glucose transporter-1  GLUT4  glucose transporter type 4  GLUTs  glucose transporters  G6P  glucose 6-phosphate, glucose transporter-1  GPR40  G protein-coupled receptor 40  HbA1c  hemoglobin A1c  HGP  hepatic glucose production  HSL  hormone sensitive lipase  IL-6  interleukin 6  INS-1  insulinoma cells in rat  IR  insulin resistance  IRS-1  insulin receptor substrate 1  JNK  c-Jun. N-terminal kinase  Kir6.2  inwardly rectifying potassium/kalium channel  LDs  lipid droplets  LDL  low density lipoprotein  LV  left ventricular  MIN6 cells  mouse insulinoma cells  MAPK  mitogen-activated protein kinases  mPTP  mitochondrial permeability transition pore opening  mTOR  mammalian target of rapamycin  NADPH  nicotinamide adenine dinucleotide phosphate  NF-kappaB  nuclear factors-kappa B  NIT-1 cells  insulinoma cells  p70S6K  p70 ribosomal S6 kinase  PA  palmitic acid  NOS  NADPH oxidase  p38 MAPK  p38 mitogen-activated protein kinase  PA  palmitic acid  PCOS  polycystic ovary syndrome  PGC-1α  peroxisome proliferator-activated receptor-g coactivator-1α  PI3K  phosphatidylinositol 3-kinase  PKB  protein kinase B  PKC  protein kinase C  PPARα  peroxisome-proliferator activated receptor α  PTP  permeability transition pore  RCT  randomized controlled trial  RISK  reperfusion injury salvage kinase  ROS  reactive oxygen species  SERCA2  reticulum sarcoplasmic Ca2 +-ATPase  RISK  reperfusion injury salvage kinase  Smad3  mothers against decapentaplegic homolog 3  SRC-2  steroid receptor coactivator 2  T1DM  Type 1 diabetes mellitus  T2DM  Type 2 diabetes mellitus  TGFβ1  transforming growth factor β1  TLR4  Toll-like receptor  TNF-α  tumor necrosis factor α  TR4  testicular receptor 4  UKPDS  United Kingdom Prospective Diabetes Study  VLDL  very low density lipoprotein  Metformin  Pancreatic β Cells  Heart failure  Insulin sensitizer  
ALDH1A1 induces resistance to CHOP in diffuse large B-cell lymphoma through activation of the JAK2/STAT3 pathway 期刊论文
OncoTargets and Therapy, 2016, 卷号: 9, 页码: 5349-5360
作者:  Jiang, Jinqiong;  Liu, Yiping;  Tang, Youhong;  Li, Li;  Zeng, Ruolan
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/03
Role of PERK/eIF2α/CHOP Endoplasmic Reticulum Stress Pathway in Oxidized Low-density Lipoprotein Mediated Induction of Endothelial Apoptosis 期刊论文
Biomedical and Environmental Sciences, 2016, 卷号: 29, 期号: 12, 页码: 868-876
作者:  Tao Yongkang;  Yu Pulin;  Bai Yongping;  Yan Shengtao;  Zhao Shuiping
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/03
Chop Deficiency Protects Mice Against Bleomycin-induced Pulmonary Fibrosis by Attenuating M2 Macrophage Production 期刊论文
Molecular Therapy, 2016, 卷号: 24, 期号: 5, 页码: 915-925
作者:  Yao, Yingying;  Wang, Yi;  Zhang, Zhijun;  He, Long;  Zhu, Jianghui
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/03
Expression of BAFF-R, but not BAFF, is an independent prognostic factor in diffuse large B-cell lymphoma patients treated with R-CHOP 期刊论文
Annals of Hematology, 2015, 卷号: 94, 期号: 11, 页码: 1865-1873
作者:  Wang, Yu;  Li, Ya-Jun;  Jiang, Wen-Qi;  Rao, Hui-Lan;  Huang, Jia-Jia
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/03
Chop deficiency prevents UUO-induced renal fibrosis by attenuating fibrotic signals originated from Hmgb1/TLR4/NFκB/IL-1β signaling 期刊论文
Cell Death & Disease, 2015, 卷号: 6, 期号: 8, 页码: e1847
作者:  Zhang, M;  Guo, Y;  Fu, H;  Hu, S;  Pan, J
收藏  |  浏览/下载:1/0  |  提交时间:2019/12/03
Annexin A5 inhibits diffuse large B-cell lymphoma cell invasion and chemoresistance through phosphatidylinositol 3-kinase signaling 期刊论文
Oncology Reports, 2014, 卷号: 32, 期号: 6, 页码: 2557-2563
作者:  Wang, Jingjing;  Zhang, Yang;  Liu, Xianling;  Ma, Jinan;  Liu, Ping
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
Nrf2 protects against furosemide-induced hepatotoxicity 期刊论文
Toxicology, 2014, 卷号: 324, 页码: 35-42
作者:  Qu, Qiang;  Liu, Jie;  Zhou, Hong-Hao;  Klaassen, Curtis D
收藏  |  浏览/下载:52/0  |  提交时间:2019/12/03
ARE  antioxidant responsive element  Bax  BCL2-associated X protein  Chop10 or Gadd153  C/Ebp-homologous protein  Egr1  early growth response factor  Gadd45  growth arrest and DNA-damage-inducible protein  Gclm  glutamate–cysteine ligase modifier subunit  Gclc  glutamate–cysteine ligase catalytic subunit  Ho-1  hemeoxygenase-1  IL-1β  interleukin 1 beta  Keap1  Kelch-like ECH-associated protein 1  MIP-2  macrophage inflammatory protein 2  mKC  mouse keratinocyte-derived chemokine  MT-1  metallothionein-1  Nqo1  NAD(P)H quinone oxidoreductase 1  Nrf2  nuclear factor E2-related factor-2  P450  cytochrome P450  STIM1  stromal interaction molecule 1  MAFG  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G  Furosemide  Nrf2  Hepatotoxicity  ER stress  Oxidative stress  Inflammation  
Down-regulation of GRP78 enhances apoptosis via CHOP pathway in retinal ischemia-reperfusion injury 期刊论文
Neuroscience letters, 2014, 卷号: 575, 页码: 68-73
作者:  Li, Huiling;  Zhu, Xiaohua;  Fang, Fang;  Jiang, Deyong;  Tang, Luosheng*
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/03


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