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吉林大学白求恩第一医... [4]
中国医学科学院 北京... [3]
山东大学 [2]
上海中医药大学 [2]
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期刊论文 [11]
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Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Li, Heng
;
Zuo, Jianping
;
Tang, Wei
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/01/08
phosphodiesterase-4
psoriasis
atopic dermatitis
inflammatory airway diseases
inflammatory bowel
disease
roflumilast
apremilast
crisaborole
Phosphodiesterase 4 Inhibitor Roflumilast Protects Rat Hippocampal Neurons from Sevoflurane Induced Injury via Modulation of MEK/ERK Signaling Pathway
期刊论文
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, 卷号: 45, 期号: 6
作者:
Peng, Sheng
;
Yan, Hong-Zhu
;
Liu, Pei-Rong
;
Shi, Xiao-Wei
;
Liu, Chun-Liang
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
Sevoflurane
Nerve damage
Roflumilast
CAMP
Phosphodiesterase 4 inhibitor (PDE-4i)
MEK/ERK pathway
Phosphodiesterase 4 Inhibitor Roflumilast Protects Rat Hippocampal Neurons from Sevoflurane Induced Injury via Modulation of MEK/ERK Signaling Pathway
期刊论文
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, 卷号: 45, 页码: 2329-2337
作者:
Peng Sheng[1]
;
Yan Hong-Zhu[2]
;
Liu Pei-Rong[3]
;
Shi Xiao-Wei[4]
;
Liu Chun-Liang[5]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/04/24
CAMP
MEK/ERK pathway
Nerve damage
Phosphodiesterase 4 inhibitor (PDE-4i)
Roflumilast
Sevoflurane
Pharmacokinetics of single- and multiple-dose roflumilast: an open-label, three-way crossover study in healthy Chinese volunteers
期刊论文
2018, 卷号: 12, 页码: 4047-4057
作者:
Huang Jie
;
Fu Cheng-Xiao
;
Yang Xiao-Yan
;
Cui Chan
;
Yang Shuang
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
healthy volunteer
pharmacokinetics
phosphodiesterase 4 inhibitor
roflumilast
roflumilast N-oxide
The phosphodiesterase-4 inhibitor roflumilast decreases ethanol consumption in C57BL/6J mice
期刊论文
PSYCHOPHARMACOLOGY, 2017, 卷号: 234, 期号: 16, 页码: 2409-2419
作者:
Liu, Xin
;
Hao, Pi-Da
;
Yang, Ming-Feng
;
Sun, Jing-Yi
;
Mao, Lei-Lei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
cAMP signaling
Phosphodiesterase-4 (PDE4)
Roflumilast
C57BL/6J mice
Ethanol consumption
Roflumilast Reduces Cerebral Inflammation in a Rat Model of Experimental Subarachnoid Hemorrhage
期刊论文
INFLAMMATION, 2017, 卷号: 40, 期号: 4, 页码: 1245-1253
作者:
Wu, Qingjian
;
Qi, Lifeng
;
Li, Hanxia
;
Mao, Leilei
;
Yang, Mingfeng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/12
subarachnoid hemorrhage
roflumilast
cerebral inflammation
Pharmacokinetics of Roflumilast and Its Active Metabolite Roflumilast N-Oxide in Healthy Chinese Subjects After Single and Multiple Oral Doses
期刊论文
2017, 卷号: 42, 期号: 3, 页码: 371-381
作者:
Li Qian
;
Wang Yiya
;
Liu Lingye
;
Ma Pengcheng
;
Ding Li
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/04
Simultaneous determination of roflumilast and its metabolite in human plasma by LC-MS/MS: Application for a pharmacokinetic study
期刊论文
2016, 卷号: 1029-1030, 页码: 60-7
作者:
Cui Xinge
;
Huang Jie
;
Zheng Xin
;
Jiang Ji
;
Kuang Yun
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
Chinese healthy volunteers
Human plasma
LC–MS/MS
Roflumilast
Roflumilast N-oxide
Synthesis of multi-substituted 4-aminopyridines via ring-opening and recyclization reactions of 2-iminopyridines
期刊论文
rsc advances, 2014, 卷号: 4, 期号: 35, 页码: 18198-18204
Zhou, Fenguo
;
Zhang, Ning
;
Xin, Xiaoqing
;
Zhang,Xun
;
Liang,Yongjiu
;
Zhang,Rui
;
Dong,Dewen
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2015/10/19
1
PYRIDINIUM SALTS
DERIVATIVES
SUBSTITUENT
MALONONITRILE
PINACIDIL
CYCLOTRIMERIZATION
ROFLUMILAST
CROMAKALIM
TORSEMIDE
3-SULFONYL SHIFT
Roflumilast for the Treatment of COPD in an Asian Population A Randomized, Double-Blind, Parallel-Group Study
期刊论文
CHEST, 2014, 卷号: 145, 期号: 1
作者:
Zheng, Jinping
;
Yang, Jinghua
;
Zhou, Xiangdong
;
Zhao, Li
;
Hui, Fuxin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/19
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