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Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors
期刊论文
BMC Medicine, 2022, 卷号: 20, 期号: 1
作者:
Zhang,Pei
;
Du,Yang
;
Bai,Hua
;
Wang,Zhijie
;
Duan,Jianchun
收藏
  |  
浏览/下载:119/0
  |  
提交时间:2022/11/21
Tucidinostat
Tumor microenvironment
PD-L1
CCL5
Solid tumor
GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhang, Qing
;
Chen, Lin-hai
;
Yang, Hui
;
Fang, You-chen
;
Wang, Si-wei
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/01/18
GPR84
medium chain fatty acid receptor
GPCR
inflammatory bowel diseases
ulcerative colitis
NLRP3 inflammasome
macrophages
An inactivated bivalent vaccine effectively protects turbot (Scophthalmus maximus) against Vibrio anguillarum and Vibrio harveyi infection
期刊论文
AQUACULTURE, 2021, 卷号: 544, 页码: 7
作者:
Zhang, Jian
;
Hu, Yonghua
;
Sun, Qinglei
;
Li, Xuepeng
;
Sun, Li
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/09/18
Bivalent vaccine
Vibriosis
Relative percentage survival (RPS)
Specific immune response
Monocytes
PTP4A3 Is a Prognostic Biomarker Correlated With Immune Infiltrates in Papillary Renal Cell Carcinoma
期刊论文
FRONTIERS IN IMMUNOLOGY, 2021, 卷号: 12
作者:
Song, Qian
;
Zheng, Yutian
;
Wu, Junzhou
;
Wang, Sheng
;
Meng, Lin
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/11/15
renal cancer
prognosis
tumor infiltration
biomarker
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yu-ting
;
Ding, Hui-hua
;
Lin, Ze-min
;
Wang, Que
;
Chen, Li
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
rheumatoid arthritis
BTK inhibitors
B cells
macrophages
RANKL
osteoclastogenesis
Ternary Regulation of Tumor Microenvironment by Heparanase-Sensitive Micelle-Loaded Monocytes Improves Chemo-Immunotherapy of Metastatic Breast Cancer
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 12
作者:
Lang, Tianqun
;
Zheng, Zhong
;
Huang, Xin
;
Liu, Yiran
;
Zhai, Yihui
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/05/24
breast cancer
chemo-immunotherapy
heparinase
monocytes
tumor environments
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-Dependent TFEB Signaling Pathway
期刊论文
CIRCULATION RESEARCH, 2020, 卷号: 127, 期号: 4, 页码: 534-549
作者:
You, Yan
;
Bao, Wei-Lian
;
Zhang, Su-Lin
;
Li, Hai-Dong
;
Li, Hui
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/12/24
atherosclerosis
foam cell
lipid metabolism
monocytes
sorting nexin
A Designed alpha-GalCer Analog Promotes Considerable Th1 Cytokine Response by Activating the CD1d-iNKT Axis and CD11b-Positive Monocytes/Macrophages
期刊论文
ADVANCED SCIENCE, 2020, 卷号: 7, 期号: 14, 页码: 1-9
作者:
Ma, Juan
;
He, Peng
;
Zhao, Chuanfang
;
Ren, Quanzhong
;
Dong, Zheng
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/09/14
antitumor activity
CD11b monocytes
CD1d
Th1-biased immune responses
alpha-GalCer analogs
Calcitriol-Loaded Dual-pH-Sensitive Micelle Counteracts Pro-Metastasis Effect of Paclitaxel in Triple-Negative Breast Cancer Therapy
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2020, 页码: 12
作者:
Zheng, Zhong
;
Lang, Tianqun
;
Huang, Xin
;
Wang, Guanru
;
Lee, Robert J.
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  |  
浏览/下载:58/0
  |  
提交时间:2020/07/01
breast cancer
calcitriol
metastasis
micelles
pH-sensitive micelles
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