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上海药物研究所 [10]
西北高原生物研究所 [10]
厦门大学 [8]
武汉物理与数学研究所 [6]
大连化学物理研究所 [5]
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Programmable DNA hydrogel provides suitable microenvironment for enhancing autophagy-based therapies in intervertebral disc degeneration treatment
期刊论文
JOURNAL OF NANOBIOTECHNOLOGY, 2023, 卷号: 21
作者:
Qingxin, Song
;
Kai, Jiang
;
Dandan, Zheng
;
Linyu, Jin
;
Xiuyuan, Chen
收藏
  |  
浏览/下载:121/0
  |  
提交时间:2023/11/10
Intervertebral disc degeneration
Gene therapy
DNA hydrogel
Autophagy
Extracellular matrix
Insights into symbiotic interactions from metatranscriptome analysis of deep-sea mussel Gigantidas platifrons under long-term laboratory maintenance
期刊论文
MOLECULAR ECOLOGY, 2022, 页码: 16
作者:
Sun, Yan
;
Wang, Minxiao
;
Chen, Hao
;
Wang, Hao
;
Zhong, Zhaoshan
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/01/04
Bathymodiolinae mussel
deep-sea endosymbioses
gene network analysis
laboratory maintenance
metatranscriptome
symbiotic interaction
A dynamic fluorescence probed glycolysis suppression process in HeLa cells treated with trichostatin A
期刊论文
ANALYST, 2022
作者:
Zhang, Fengqiu
;
Shao, Changsheng
;
Wu, Yahui
;
Zhao, Wei
;
Jing, Xumiao
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/12/22
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:
He, Yu-Long
;
Chen, Meng-Ting
;
Wang, Ting
;
Zhang, Ming-Ming
;
Li, Ying-Xia
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2021/11/04
Type 2 diabetes mellitus
Dual FABP4/5 inhibitors
Anti-lipolytic and anti-inflammatory effects
Metabolic stability
Anti-diabetic activities
Microbiome-Metabolomics Reveals Prebiotic Benefits of Fucoidan Supplementation in Mice
期刊论文
JOURNAL OF MARINE SCIENCE AND ENGINEERING, 2021, 卷号: 9, 期号: 5, 页码: 13
作者:
Yuan, Jingyi
;
Qin, Song
;
Li, Wenjun
;
Zhang, Yubing
;
Wang, Yuting
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
fucoidan
microbiome
metabolomics
gut microbiota
Surviving winter on the Qinghai-Tibetan Plateau: Pikas suppress energy demands and exploit yak feces to survive winter
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 30
作者:
Speakman, John R.
;
Chi, Qingsheng
;
Oldakowski, Lukasz
;
Fu, Haibo
;
Fletcher, Quinn E.
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/11/18
winter survival
metabolic suppression
thyroid axis
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
Transcriptional and metabolic response against hydroxyethane-(1,1-bisphosphonic acid) on bacterial denitrification by a halophilic Pannonibacter sp. strain DN
期刊论文
CHEMOSPHERE, 2020, 卷号: 252, 页码: 1-11
作者:
Koju, Rashmi
;
Miao, Shiyu
;
Liang, Bin
;
Joshi, Dev Raj
;
Bai, Yaohui
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/09/15
Hydroxyethane-(1,1-bisphosphonic acid)
Denitrification
Pannonibacter sp. DN
Membrane potential
Transcriptional profiling
Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Yu, Yan-yan
;
Cui, Shi-chao
;
Zheng, Tian-nan
;
Ma, Hai-jian
;
Xie, Zhi-fu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
insulin resistance
sarsasapogenin
adipose tissue inflammation
macrophage-adipocyte crosstalk
IKK/NF-kappa B
JNK
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