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Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2
期刊论文
LEUKEMIA, 2022
作者:
Yang, Jing
;
Weisberg, Ellen L.
;
Qi, Shuang
;
Ni, Wei
;
Mei, Husheng
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/02/14
Effect of donor characteristics on T cell-replete haploidentical stem cell transplantation over the last 10 years at a single institution
期刊论文
BRITISH JOURNAL OF HAEMATOLOGY, 2021
作者:
Wu, Yibo
;
Lai, Xiaoyu
;
Shi, Jimin
;
Tan, Yamin
;
Zhao, Yanmin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/01/10
haploidentical
haematopoietic stem cell transplantation
donor selection
donor characteristics
donor age
female to male
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Jiang, Kai-long
;
Tong, Le-xian
;
Wang, Tao
;
Wang, Han-lin
;
Hu, Xiao-bei
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/05/24
CHK1 inhibitors
PY34
drug sensitivity
c-Myc
hematologic malignancies
Isocitrate Dehydrogenase 2 Inhibitors for the Treatment of Hematologic Malignancies: Advances and Future Opportunities
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21
作者:
Huang, Feng
;
Tian, Tian
;
Wu, Yizhe
;
Che, Jinxin
;
Yang, Haiyan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/06/15
Isocitrate dehydrogenase 2
IDH2
mutant
inhibitors
structure-activity relationship
blood cance
Inhibition of deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2
期刊论文
LEUKEMIA, 2021
作者:
Qi S(亓爽)
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/12/09
The Predictive Value of Pre-therapeutic Serum Gamma-glutamyl transferase in Efficacy and Adverse Reactions to Neoadjuvant Chemotherapy among Breast Cancer Patients
期刊论文
JOURNAL OF BREAST CANCER, 2020, 卷号: 23
作者:
Sun, Lu
;
Yin, Wenjin
;
Wu, Ziping
;
Wang, Yaohui
;
Lu, Jinsong
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/12/28
Breast cancer
Gamma-glutamyltransferase
Neoadjuvant therapy
Chemotherapy
Prognosis
Circular Bispecific Aptamer-Mediated Artificial Intercellular Recognition for Targeted T Cell Immunotherapy
期刊论文
ACS NANO, 2020, 卷号: 14
作者:
Yang, Yu
;
Sun, Xiaoqi
;
Xu, Jun
;
Cui, Cheng
;
Yazd, Hoda Safari
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  |  
浏览/下载:40/0
  |  
提交时间:2020/10/26
recognition-then-activation
circular bispecific aptamer
cb-aptamer
adoptive T cell immunotherapy
T cell immunotherapy
on shelf
Nanotechnology-Based Histone Deacetylase Inhibitors for Cancer Therapy
期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 卷号: 8, 页码: 8
作者:
Tu, Bin
;
Zhang, Meng
;
Liu, Tuanbing
;
Huang, Yongzhuo
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2020/12/24
Histone deacetylase inhibitors (HDACi)
nanotechnology
nanomedicine
cancer therapy
solid tumor
targeting drug delivery
combination therapy
The novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Hao, Bing-bing
;
Li, Xiao-jing
;
Jia, Xing-long
;
Wang, Yu-xing
;
Zhai, Lin-hui
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
immunomodulatory drugs (IMiDs)
CC-885
BNIP3L
mitophagy
CRBN
acute myeloid leukemia
mitochondria-targeting drugs
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