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A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:  Zhou, Jun;  Zhan, Yan;  Zhong, Dafang;  Chen, Xiaoyan;  Zhang, Yifan
收藏  |  浏览/下载:70/0  |  提交时间:2021/11/04
Pharmacokinetic evaluation of the anticancer prodrug simmitecan in different experimental animals 期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 11, 页码: 1437-1448
作者:  Hu, Zhe-yi;  Li, Xiu-xue;  Du, Fei-fei;  Yang, Jun-ling;  Niu, Wei
收藏  |  浏览/下载:22/0  |  提交时间:2019/01/08
Accurate determination of the anticancer prodrug simmitecan and its active metabolite chimmitecan in various plasma samples based on immediate deactivation of blood carboxylesterases 期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2011, 卷号: 1218, 期号: 38, 页码: 6646-6653
作者:  Hu, Zheyi;  Sun, Yan;  Du, Feifei;  Niu, Wei;  Xu, Fang
收藏  |  浏览/下载:19/0  |  提交时间:2019/01/08
Accurate determination of the anticancer prodrug simmitecan and its active metabolite chimmitecan in various plasma samples based on immediate deactivation of blood carboxylesterases 会议论文
作者:  Hu, Zheyi;  Sun, Yan;  Li, Chuan
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08
Chk1 and Chk2 are differentially involved in homologous recombination repair and cell cycle arrest in response to DNA double-strand breaks induced by camptothecins 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2008, 卷号: 7, 期号: 6, 页码: 1440-1449
作者:  Huang, Min;  Miao, Ze-Hong;  Zhu, Hong;  Cai, Yu-Jun;  Lu, Wei
收藏  |  浏览/下载:9/0  |  提交时间:2019/01/08
Chimmitecan引起肿瘤细胞周期阻滞和DNA损伤修复关系研究 会议论文
作者:  黄敏;  朱虹;  缪泽鸿;  蔡育军;  吕伟
收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08
Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo 期刊论文
CLINICAL CANCER RESEARCH, 2007, 卷号: 13, 期号: 4, 页码: 1298-1307
作者:  Huang, Min;  Gao, Heyong;  Chen, Yi;  Zhu, Hong;  Cai, Yujun
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08
Anticancer agents discovery from nature products 会议论文
作者:  Ding, Jian
收藏  |  浏览/下载:7/0  |  提交时间:2019/01/08


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