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牙鲆基因编辑技术构建及其应用的初步研究
学位论文
中国科学院海洋研究所: 中国科学院大学, 2021
作者:
王凌
收藏
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浏览/下载:45/0
  |  
提交时间:2021/06/05
牙鲆,显微注射及电转,CRISPR/Cas9系统,PGC迁移因子,dnali1
The association of CMTM6 expression with prognosis and PD-L1 expression in triple-negative breast cancer
期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9
作者:
Tian, Yiping
;
Sun, Xiaohui
;
Cheng, Guoping
;
Ji, Enming
;
Yang, Shifeng
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/17
CMTM6
PD-L1
triple-negative breast cancer (TNBC)
immunohistochemistry (IHC)
polymerase chain reaction (PCR)
prognosis
CKLF1 Aggravates Focal Cerebral Ischemia Injury at Early Stage Partly by Modulating Microglia/Macrophage Toward M1 Polarization Through CCR4
期刊论文
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2019, 卷号: 39, 期号: 5, 页码: 651, 669
作者:
Chen, C
;
Chu, SF
;
Ai, QD
;
Zhang, Z
;
Guan, FF
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  |  
浏览/下载:78/0
  |  
提交时间:2019/06/14
CKLF1
CHEMOKINE-LIKE FACTOR-1
CCR4
SEX-DIFFERENCES
Ischemic stroke
REPERFUSION INJURY
Microglia
RECEPTOR 5
macrophage
STROKE
Polarization
BRAIN
ACTIVATION
EXPRESSION
MICROGLIA
MECHANISM
CKLF1 aggravates neointimal hyperplasia by inhibiting apoptosis of vascular smooth muscle cells through PI3K/AKT/NF-kappa B signaling
期刊论文
2019, 卷号: 117, 页码: 108986
作者:
Duan, Yanyu
;
Zhang, Yongbao
;
Qu, Chengjia
;
Yu, Weidong
;
Tana
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/01/03
Chemokine-like factor 1
Vascular smooth muscle cells
Apoptosis
Neointimal hyperplasia
PI3 kinase
IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation
期刊论文
2019, 卷号: 212, 页码: 36-53
作者:
Ai Q D
;
Chen Chen
;
Chu Shifeng
;
Zhang Zhao
;
Luo Yun
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  |  
浏览/下载:26/0
  |  
提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain
BCA = bicinchoninic acid
BSA = bovine serum albumin
CCA = common carotid artery
CCR4 = C-C chemokine receptor type 4
CKLF1 = chemokine-like factor 1
CO-IP = coimmunoprecipitation
ECA = external carotid artery
ELISA = enzyme-linked immunosorbent assay
FDA = Food and Drug Administration
I/R = ischemic/reperfusion
ICA = internal carotid artery
IL-18 = interleukin 18
IL-1β = interleukin 1β
LDH = lactate dehydrogenase
NLRP3 = NOD-like receptor protein 3
PBS = phosphate-buffered saline
SD = standard deviation
TNF-α = tumor necrosis factor α
TTC = 2
3
5-triphenyltetrazolium-chloride
WT = wild-type
pMCAO = permanent middle cerebral artery occlusion
pro-Caspase-1 = precursor Caspase-1
qPCR = quantitative real-time PCR
tMCAO = transient middle cerebral artery occlusion
tPA = tissue plasminogen activator
Fibroblast Growth Factor 2 Modulates Hippocampal Microglia Activation in a Neuroinflammation Induced Model of Depression
期刊论文
FRONTIERS IN CELLULAR NEUROSCIENCE, 2018, 卷号: 12, 页码: 14
作者:
Tang, Ming-ming
;
Lin, Wen-juan
;
Pan, Yu-qin
;
Li, Ying-cong
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2018/09/10
Fibroblast Growth Factor 2
Microglia
Depressive-like Behavior
Neuroinflammation
Cytokines
Cx3cl1
Hippocampus
Progress in pharmacological research of chemokine like factor 1 (CKLF1)
期刊论文
2018, 卷号: 102, 页码: 41-50
作者:
Liu, Dan-Dan
;
Song, Xiu-Yun
;
Yang, Peng-Fei
;
Ai, Qi-Di
;
Wang, Ying-Ying
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/01/03
Chemokine like factor 1
C19 peptide
C27 peptide
CCR4
Allergic diseases
Autoimmune diseases
Progress in pharmacological research of chemokine like factor 1 (CKLF1)
期刊论文
Cytokine, 2018, 卷号: 102, 页码: 41-50
作者:
Liu, Dan-Dan
;
Song, Xiu-Yun
;
Yang, Peng-Fei
;
Ai, Qi-Di
;
Wang, Ying-Ying
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/27
Chemokine like factor 1
C19 peptide
C27 peptide
CCR4
Allergic diseases
Autoimmune diseases
Chemokines play complex roles in cerebral ischemia
期刊论文
Neurochemistry International, 2018, 卷号: 112, 页码: 146-158
作者:
Chen, Chen
;
Chu, Shi-Feng
;
Liu, Dan-Dan
;
Zhang, Zhao
;
Kong, Ling-Lei
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/12/27
Chemokine
Cerebral ischemia
Ischemic stroke
IS
ischemic stroke
NSCs
neural stem cell
NPCs
neural progenitor cells
BMSCs
bone marrow stromal cells
ELR
glutamic acid-leucine-arginine
MCP
monocytes chemoattractant protein
MCAo
middle cerebral artery occlusion
tMCAo
transient MCAo
CNS
central nervous system
MIP
macrophage inflammatory protein
BBB
blood brain barrier
HI
hypoxia ischemia
CSF
cerebrospinal fluid
CI
cerebral infarction
WT
wildtype
pMCAo
permanent MCAo
ET
endothelin
I/R
ischemia/reperfusion
SCID
Severe Combined Immunodeficiency
ENA-78
epithelial neutrophil-activating peptide-78
IL-8
interleukin 8
PMNL
polymorphonuclear leukocyte
MSCs
mesenchymal stem cells
VEGF
vascular endothelial growth factor
CINC
cytokine-induced neutrophil chemoattractant
IP-10
interferon-gamma inducible protein-10
NK
natural killer
SDF-1
stromal cell-derived factor-1
EPCs
endothelial progenitor cells
HSCs
hematopoietic stem cells
HUVECs
human umbilical vein endothelial cells
TIA
transient ischemic attack
OGD
oxygen glucose deprivation
GPCs
glial precursor cells
CMKLR1
chemerin-like receptor-1
AIS
acute ischemic stroke
CKLF1
chemokine-like factor 1
CBP
chemokine-binding protein
Construction and expression of DNA vaccine against reddish body iridovirus and evaluation of immune efficacy in turbot (Scophthalmus maximus)
期刊论文
AQUACULTURE RESEARCH, 2017, 卷号: 48, 期号: 8, 页码: 4174-4183
作者:
Zheng, Fengrong
;
Liu, Hongzhan
;
Sun, Xiuqin
;
Qin, Xiaoping
;
Xu, Zongjun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/08/19
eukaryotic expression vector construction
turbot reddish body iridovirus
immune response
immune efficacy
DNA vaccine
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