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	IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation
	Ai Q D; Chen Chen; Chu Shifeng; Zhang Zhao; Luo Yun; Guan Feifei; Lin Meiyu; Liu Dandan; Wang Shasha; Chen Naihong
	2019
卷号	212页码:36-53
关键词	ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain BCA = bicinchoninic acid BSA = bovine serum albumin CCA = common carotid artery CCR4 = C-C chemokine receptor type 4 CKLF1 = chemokine-like factor 1 CO-IP = coimmunoprecipitation ECA = external carotid artery ELISA = enzyme-linked immunosorbent assay FDA = Food and Drug Administration I/R = ischemic/reperfusion ICA = internal carotid artery IL-18 = interleukin 18 IL-1β = interleukin 1β LDH = lactate dehydrogenase NLRP3 = NOD-like receptor protein 3 PBS = phosphate-buffered saline SD = standard deviation TNF-α = tumor necrosis factor α TTC = 2 3 5-triphenyltetrazolium-chloride WT = wild-type pMCAO = permanent middle cerebral artery occlusion pro-Caspase-1 = precursor Caspase-1 qPCR = quantitative real-time PCR tMCAO = transient middle cerebral artery occlusion tPA = tissue plasminogen activator
ISSN号	1878-1810
DOI	10.1016/j.trsl.2019.05.007
URL标识	查看原文
收录类别	PUBMED
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/6340914
专题	中国医学科学院 北京协和医学院
推荐引用方式 GB/T 7714	Ai Q D,Chen Chen,Chu Shifeng,et al. IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation[J],2019,212:36-53.
APA	Ai Q D.,Chen Chen.,Chu Shifeng.,Zhang Zhao.,Luo Yun.,...&Chen Naihong.(2019).IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation.,212,36-53.
MLA	Ai Q D,et al."IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation".212(2019):36-53.

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