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Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 18
作者:
Lan, Xiao-fang
;
Olaleye, Olajide E.
;
Lu, Jun-lan
;
Yang, Wei
;
Du, Fei-fei
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/06/11
LianhuaQingwen
glycyrrhetic acid
24-hydroxyglycyrrhetic acid
Gancao-induced pseudoaldosteronism
licorice-induced pseudoaldosteronism
11β
-hydroxysteroid dehydrogenase 2
COVID-19
colonic microbiota
Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Meng, Jian
;
Zhang, Hua
;
Bao, Jing-jing
;
Chen, Zhen-dong
;
Liu, Xiao-yun
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  |  
浏览/下载:69/0
  |  
提交时间:2021/06/11
metabolism
mass balance
distribution
covalent binding
furmonertinib
Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Meng, Jian
;
Zhang, Hua
;
Bao, Jing-jing
;
Chen, Zhen-dong
;
Liu, Xiao-yun
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/06/11
metabolism
mass balance
distribution
covalent binding
furmonertinib
Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:
Qiao, Shida
;
Feng, Sisi
;
Wu, Zhitao
;
He, Ting
;
Ma, Chen
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  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Zheng, Yuan-dong
;
Zhang, Hua
;
Zhan, Yan
;
Bian, Yi-cong
;
Ma, Sheng
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  |  
浏览/下载:42/0
  |  
提交时间:2021/05/24
vicagrel
[C-14]vicagrel
vicagrel pharmacokinetics
vicagrel metabolism
mass balance
P2Y(12) receptor inhibitor
leflunomideincreasedtherenalexposureofacyclovirbyinhibitingoat13andmrp2
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 1, 页码: 129
作者:
Liao Xiaoying
;
Deng Qiangqiang
;
Han Li
;
Wu Zhitao
;
Peng Zhaoliang
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  |  
浏览/下载:83/0
  |  
提交时间:2020/07/01
leflunomide
teriflunomide
acyclovir
organic anion transporter
multidrug resistance associated protein (MRP) 2
drugdrug interaction
pharmacokinetics
Leflunomide increased the renal exposure of acyclovir by inhibiting OAT1/3 and MRP2
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 1, 页码: 129-137
作者:
Liao, Xiao-ying
;
Deng, Qiang-qiang
;
Han, Li
;
Wu, Zhi-tao
;
Peng, Zhao-liang
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  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
leflunomide
teriflunomide
acyclovir
organic anion transporter
multidrug resistance associated protein (MRP) 2
drug-drug interaction
pharmacokinetics
Identifying the active components of Baihe-Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests
期刊论文
CHINESE MEDICINE, 2019, 卷号: 14, 期号: 1, 页码: 11
作者:
Zhong, Ming
;
Tian, Xiaoting
;
Chen, Shuoji
;
Chen, Mingcang
;
Guo, Ziqiong
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Baihe-Zhimu decoction
Antidepressant
Timosaponin BII
Timosaponin BIII
Drug discovery
High degree of pharmacokinetic compatibility exists between the five-herb medicine XueBiJing and antibiotics comedicated in sepsis care
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 5, 页码: 1035-1049
作者:
Li, Jian
;
Olaleye, Olajide E.
;
Yu, Xuan
;
Jia, Weiwei
;
Yang, Junling
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
XueBiJing
Antibiotic
Combination drug therapy
Sepsis
Pharmacokinetic compatibility
Herb-drug interaction
Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans
期刊论文
DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 8, 页码: 843-853
作者:
Li, Xiuli
;
Sun, Jingchao
;
Guo, Zitao
;
Zhong, Dafang
;
Chen, Xiaoyan
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  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
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