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科研机构
上海药物研究所 [27]
内容类型
期刊论文 [27]
发表日期
2021 [2]
2020 [5]
2019 [2]
2018 [4]
2017 [1]
2016 [2]
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Itraconazole and rifampicin, as CYP3A modulators but not P-gp modulators, affect the pharmacokinetics of almonertinib and active metabolite HAS-719 in healthy volunteers
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Liu, Lu
;
Li, Wei
;
Yang, Le
;
Guo, Zi-tao
;
Xue, Hao
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2021/08/17
almonertinib
itraconazole
rifampicin
drug metabolism
drug interaction
CYP3A
P-gp
pharmacokinetics
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Jiang, Kai-long
;
Tong, Le-xian
;
Wang, Tao
;
Wang, Han-lin
;
Hu, Xiao-bei
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/05/24
CHK1 inhibitors
PY34
drug sensitivity
c-Myc
hematologic malignancies
Neuroprotective and Anti-inflammatory Ditetrahydrofuran-Containing Diarylheptanoids from Tacca chantrieri
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2020, 卷号: 83, 期号: 12, 页码: 3681-3688
作者:
Yang, Yue
;
Gong, Qi
;
Wang, Wei
;
Mao, Ying-Le
;
Wang, Xiao-Rong
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2021/05/24
Photochromic Fluorescent Probe Strategy for the Super-resolution Imaging of Biologically Important Biomarkers
期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 卷号: 142, 期号: 42, 页码: 18005-18013
作者:
Chai, Xianzhi
;
Han, Hai-Hao
;
Sedgwick, Adam C.
;
Li, Na
;
Zang, Yi
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/24
Revelation of AbfR in regulation of mismatch repair and energy metabolism in S. epidermidis by integrated proteomic and metabolomic analysis
期刊论文
JOURNAL OF PROTEOMICS, 2020, 卷号: 226, 页码: 10
作者:
Gu, Lei
;
Liu, Xing
;
Wang, Yu-Qiu
;
Zhou, Yan-ting
;
Zhu, Hong-wen
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/21
Staphylococcus epidermidis
AbfR transcription factor
Oxidation-sensing regulator
Oxidative stress
TMT10-plex labelling
Antibiotic resistance regulator
Revelation of AbfR in regulation of mismatch repair and energy metabolism in S. epidermidis by integrated proteomic and metabolomic analysis
期刊论文
JOURNAL OF PROTEOMICS, 2020, 卷号: 226, 页码: 10
作者:
Gu, Lei
;
Liu, Xing
;
Wang, Yu-Qiu
;
Zhou, Yan-ting
;
Zhu, Hong-wen
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
Staphylococcus epidermidis
AbfR transcription factor
Oxidation-sensing regulator
Oxidative stress
TMT10-plex labelling
Antibiotic resistance regulator
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 14
作者:
Xue, Ya-ru
;
Yao, Sheng
;
Liu, Qian
;
Peng, Zhao-liang
;
Deng, Qiang-qiang
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/07/01
gigantol
Chinese traditional medicine
liver injury
oxidative stress
inflammation
label-free proteomic
complement and coagulation cascades
terminal complement complex
Exploration of the structure-activity relationship and druggability of novel oxazolidinone-based compounds as Gram-negative antibacterial agents
期刊论文
ARCHIV DER PHARMAZIE, 2019, 页码: 13
作者:
Ding, Shi
;
Ji, Jing-Chao
;
Zhang, Ming-Juan
;
Yang, Yu-She
;
Wang, Rui
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
antibacterial activity
oxazolidine
QSAR
Modelling liver cancer initiation with organoids derived from directly reprogrammed human hepatocytes
期刊论文
NATURE CELL BIOLOGY, 2019, 卷号: 21, 期号: 8, 页码: 1015-+
作者:
Sun, Lulu
;
Wang, Yuqing
;
Cen, Jin
;
Ma, Xiaolong
;
Cui, Lei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Anticancer drug discovery from Chinese medicinal herbs
期刊论文
CHINESE MEDICINE, 2018, 卷号: 13
作者:
Huang, Mu-Yang
;
Zhang, Le-Le
;
Ding, Jian
;
Lu, Jin-Jian
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Chinese medicinal herbs
Anticancer
Drug discovery
Natural products
Formulae
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