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CORC

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Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10
作者:  Xiang, Hao-Yue;  Wang, Xiang;  Chen, Yan-Hong;  Zhang, Xi;  Tan, Cun
收藏  |  浏览/下载：35/0  |  提交时间：2021/05/24
Design, synthesis and antiproliferative activity evaluation of a series of pyrrolo [2,1-f] [1,2,4] triazine derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 12, 页码: 4
作者:  Xiang, Hao-Yue;  Chen, Yan-Hong;  Wang, Yi;  Zhang, Xi;  Ding, Jian
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01
Design, synthesis, and biological evaluation of 1,2,5-oxadiazole-3-carboximidamide derivatives as novel indoleamine-2,3-dioxygenase 1 inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 189, 页码: 14
作者:  Song, Xiaohan;  Sun, Pu;  Wang, Jiang;  Guo, Wei;  Wang, Yi
收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01
Decrease in phosphorylated ERK indicates the therapeutic efficacy of a clinical PI3K alpha-selective inhibitor CYH33 in breast cancer 期刊论文
CANCER LETTERS, 2018, 卷号: 433, 页码: 273-282
作者:  Liu, Xue-ling;  Xu, Yi-chao;  Wang, Yu-xiang;  Chen, Yi;  Wang, Bo-bo
收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08
Dicer1/miR-29/HMGCR axis contributes to hepatic free cholesterol accumulation in mouse nonalcoholic steatohepatitis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 5, 页码: 660-671
作者:  Liu, Ming-xia;  Gao, Man;  Li, Chun-zhu;  Yu, Cun-zhi;  Yan, Hong
收藏  |  浏览/下载：54/0  |  提交时间：2019/01/08
MicroRNA-1304 suppresses human non-small cell lung cancer cell growth in vitro by targeting heme oxygenase-1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 1, 页码: 110-119
作者:  Li, Cheng-gang;  Pu, Meng-fan;  Li, Chun-zhu;  Gao, Man;  Liu, Ming-xia
收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08
PH006, a novel and selective Src kinase inhibitor, suppresses human breast cancer growth and metastasis in vitro and in vivo 期刊论文
BREAST CANCER RESEARCH AND TREATMENT, 2011, 卷号: 130, 期号: 1, 页码: 85-96
作者:  Ma, Jin-gui;  Huang, He;  Chen, Si-meng;  Chen, Yi;  Xin, Xian-liang
收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08
Application of the theories of materiomic release kinetics to the evaluation of the sustained release kinetics and synchronicity of yinqiaojiedu honeyed pills 会议论文
作者:  Ling, Die;  Zhang, Ji-Wen;  Chen, Li-Bing;  Lin, Meng;  Ge, Wei-Hong
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Emerging cancer therapeutic opportunities target DNA-repair systems 期刊论文
TRENDS IN PHARMACOLOGICAL SCIENCES, 2006, 卷号: 27, 期号: 6, 页码: 338-344
作者:  Ding, Jian;  Miao, Ze-Hong;  Meng, Ling-Hua;  Geng, Mei-Yu
收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08

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