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科研机构
上海药物研究所 [124]
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期刊论文 [122]
会议论文 [1]
学位论文 [1]
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2021 [8]
2020 [4]
2019 [7]
2018 [17]
2017 [11]
2016 [5]
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Improving Stability of Vitamin B5 Through Double Salt Formation
期刊论文
CRYSTAL GROWTH & DESIGN, 2021, 卷号: 21, 期号: 9, 页码: 4997-5005
作者:
Liang, Xuan
;
Zhang, Qi
;
Zhang, Zaiyong
;
Ding, Qiaoce
;
Mei, Xuefeng
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/11/04
Molecular simulation studies of the interactions between the human/ pangolin/cat/bat ACE2 and the receptor binding domain of the SARS-CoV-2 spike protein
期刊论文
BIOCHIMIE, 2021, 卷号: 187, 页码: 1-13
作者:
Ma, Shaojie
;
Li, Hui
;
Yang, Jun
;
Yu, Kunqian
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/08/17
SARS-CoV-2
ACE2
Molecular simulation
Binding energy
Animal hosts
Liquid chromatography-mass spectrometry method for the quantification of an anti-sclerostin monoclonal antibody in cynomolgus monkey serum
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2021, 卷号: 11, 期号: 4, 页码: 472-479
作者:
Gao, Yuxiong
;
Chen, Zhendong
;
Yang, Changyong
;
Zhong, Dafang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/11/04
Anti-sclerostin monoclonal antibody (SHR-1222)
LC-MS/MS
Anti-drug antibody
Toxicokinetic
Expression, purification and characterization of the second DUSP domain of deubiquitinase USP20/VDU2
期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2021, 卷号: 181, 页码: 6
作者:
Hu, Shuwei
;
Chen, Xiaoyu
;
Zhu, Mengying
;
Hu, Huifang
;
Zhou, Chen
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/05/24
Deubiquitinase
USP20
DUSP domain
NMR
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:
Wu, Xiaowei
;
Dai, Mengdi
;
Cui, Rongrong
;
Wang, Yulan
;
Li, Chunpu
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
Tyrosine kinase
Covalent FGFR inhibitors
Virtual screening
Pyrazolo[3,4-d] pyridazinone
Structure-activity relationships
Antitumor efficacy
Challenges and stepwise fit-for-purpose optimization for bioanalyses of remdesivir metabolites nucleotide monophosphate and triphosphate in mouse tissues using LC-MS/MS
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 194, 页码: 10
作者:
Hu, Wenjuan
;
Chang, Lu
;
Ke, Changqiang
;
Xie, Yuanchao
;
Shen, Jingshan
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
Remdesivir
Nucleotide monophosphate
Nucleotide triphosphate
Stability
Recovery
LC-MS/MS
Different Solid Forms of Vitamin K-3 and Their Effect on the Chemical Stability
期刊论文
CRYSTAL GROWTH & DESIGN, 2021, 卷号: 21, 期号: 1, 页码: 528-535
作者:
Yang, Zeen
;
Zhu, Bingqing
;
Jiang, Yuhang
;
Zhang, Zaiyong
;
Dai, Wenjuan
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  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and osteoclastogenesis
期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 20, 页码: 9821-9832
作者:
Li, Xiaoxun
;
Liang, Yajun
;
Lian, Cheng
;
Peng, Fangli
;
Xiao, Yansen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/01/04
Breast cancer
Bone metastasis
Osteoclastogenesis
CST6
Peptide drug
Intrinsic stability study of L-alpha-glycerylphosphorylcholine with HPLC method development and validation
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 188, 页码: 6
作者:
Zhao, Hongwei
;
Sun, Ling
;
Chen, Huanhuan
;
Xiang, Lili
;
Chen, Dongying
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/12/24
L-alpha-Glycerylphosphorylcholine
Phosphate ester bond
Forced degradation
HPLC
Intrinsic stability
Kinetics study
Drug-Drug Cocrystals Provide Significant Improvements of Drug Properties in Treatment with Progesterone
期刊论文
CRYSTAL GROWTH & DESIGN, 2020, 卷号: 20, 期号: 5, 页码: 3053-3063
作者:
Guo, Chunyang
;
Zhang, Qi
;
Zhu, Bingqing
;
Zhang, Zaiyong
;
Ma, Xiaoyu
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
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