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Metabolic analysis of Panax notoginseng saponins with gut microbiota-mediated biotransformation by HPLC-DAD-Q-TOF-MS/MS 期刊论文
Journal of Pharmaceutical and Biomedical Analysis, 2018, 卷号: 150, 页码: 199-207
作者:  Chen, Man-Yun;  Shao, Li;  Zhang, Wei;  Wang, Chong-Zhi;  Zhou, Hong-Hao
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/27
ACN  acetonitrile  DAD  diode array-detector  DMSO  dimethyl sulphoxide  ESI  electrospray ionization  GAM  general anaerobic medium  GF1  ginsenoside F1  GC-K  ginsenoside compound K  GRh2  ginsenoside Rh2  HF-HP  high-fat and high-protein  HPLC-DAD-Q-TOF-MS/MS  high-performance liquid chromatography coupled with diode array detection/quadrupole tandem time-of-flight mass spectrometry  LF-PF  low-fat and plant fiber-rich  LLE  liquid-liquid extraction  PPD  protopanaxadiol  PPT  protopanaxatriol  PNS  Panax notoginseng saponins  RSDs  relative standard deviations  SEM  standard deviation of mean  TICs  total ion chromatograms  Panax notoginseng  Ginsenosides  Gut microbiota  Biotransformation  Metabolic profile  HPLCDAD-Q-TOF-MS/MS  
Detection of of 1,N-2-propano-2 '-deoxyguanosine adducts in genomic DNA by ultrahigh performance liquid chromatography-electrospray ionization-tandem mass spectrometry in combination with stable isotope dilution 期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2016, 卷号: 1450, 期号: 0, 页码: 38-44
作者:  Zhang, Ning;  Song, Yuanyuan;  Wu, Danni;  Xu, Tian;  Lu, Meiling
收藏  |  浏览/下载:23/0  |  提交时间:2017/03/27
Syntheses of coumarin-tacrine hybrids as dual-site acetylcholinesterase inhibitors and their activity against butylcholinesterase, A beta aggregation, and beta-secretase 期刊论文
Bioorganic and Medicinal Chemistry, 2014, 卷号: 22, 期号: 17, 页码: 4784-4791
作者:  Sun, Qi;  Peng, Da-Yong;  Yang, Sheng-Gang;  Zhu, Xiao-Lei;  Yang, Wen-Chao*
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/23
Activity-guided isolation of NF-κB inhibitors and PPARγ agonists from the root bark of Lycium chinense Miller 期刊论文
Journal of Ethnopharmacology, 2014, 卷号: 152, 期号: 3, 页码: 470-477
作者:  Xie, Lian-Wu;  Atanasov, Atanas G.;  Guo, De-An;  Malainer, Clemens;  Zhang, Jing-Xian
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/28
1D NMR  one-dimensional nuclear magnetic resonance spectroscopy  2D NMR  two-dimensional nuclear magnetic resonance spectroscopy  ANOVA  analysis of variance  AP-1  activator protein 1  CC  column chromatography  CDCl3  deuterated chloroform  C/EBP  CCAAT/enhancer binding protein  CHCl3  chloroform  COSY  correlation spectroscopy in 2D NMR  DCM  dichloromethane  EGFP  enhanced green fluorescent protein  ESI-MS  electrospray ionization mass spectrometry  DMEM  Dulbecco׳s modified Eagle׳s medium  DMSO  dimethyl sulfoxide  EtOAc  ethyl acetate  EtOH  ethanol  FBS  fetal bovine serum  HEK293  human embryonic kidney 293  HMBC  heteronuclear multiple-bond correlation spectroscopy in 2D NMR  HPLC  high performance liquid chromatography  HSQC  heteronuclear single-quantum correlation spectroscopy in 2D NMR  IC50  half maximal inhibitory concentration  IκB  inhibitor of kappa B  IL-6  interleukin 6  IL-1β  interleukin-1 beta  MeOH  methanol  NF-κB  nuclear factor κB  NMR  nuclear magnetic resonance spectroscopy  PE  petroleum ether  PPARγ  peroxisome proliferator-activated receptor γ  TCM  traditional Chinese medicine  TLC  thin layer chromatography  TNF-α  tumor necrosis factor α  Trans-N-(p-coumaroyl)tyramine (PubChem CID: 5372945)  Trans-N-feruloyltyramine (PubChem CID: 5280537)  Trans-N-caffeoyltyramine (PubChem CID: 9994897)  Dihydro-N-caffeoyltyramine (PubChem CID: 16119668)  CHEMBL2337120 (PubChem CID: 71524307)  CHEMBL2337119 (PubChem CID: 71524308)  CHEMBL2337118 (PubChem CID: 71524309)  CHEMBL2337115 (PubChem CID: 71719510)  CHEMBL2337117 (PubChem CID: 71524310)  Lycium chinense Miller  Lycii Radicis Cortex  NF-κB  PPARγ  Phenolic amides  Fatty acids  
Activity-guided isolation of NF-κB inhibitors and PPARγ agonists from the root bark of Lycium chinense Miller 期刊论文
Journal of Ethnopharmacology, 2014, 卷号: 152, 期号: 3, 页码: 470-477
作者:  Xie, Lian-Wu;  Atanasov, Atanas G.;  Guo, De-An;  Malainer, Clemens;  Zhang, Jing-Xian
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/27
1D NMR  one-dimensional nuclear magnetic resonance spectroscopy  2D NMR  two-dimensional nuclear magnetic resonance spectroscopy  ANOVA  analysis of variance  AP-1  activator protein 1  CC  column chromatography  CDCl3  deuterated chloroform  C/EBP  CCAAT/enhancer binding protein  CHCl3  chloroform  COSY  correlation spectroscopy in 2D NMR  DCM  dichloromethane  EGFP  enhanced green fluorescent protein  ESI-MS  electrospray ionization mass spectrometry  DMEM  Dulbecco׳s modified Eagle׳s medium  DMSO  dimethyl sulfoxide  EtOAc  ethyl acetate  EtOH  ethanol  FBS  fetal bovine serum  HEK293  human embryonic kidney 293  HMBC  heteronuclear multiple-bond correlation spectroscopy in 2D NMR  HPLC  high performance liquid chromatography  HSQC  heteronuclear single-quantum correlation spectroscopy in 2D NMR  IC50  half maximal inhibitory concentration  IκB  inhibitor of kappa B  IL-6  interleukin 6  IL-1β  interleukin-1 beta  MeOH  methanol  NF-κB  nuclear factor κB  NMR  nuclear magnetic resonance spectroscopy  PE  petroleum ether  PPARγ  peroxisome proliferator-activated receptor γ  TCM  traditional Chinese medicine  TLC  thin layer chromatography  TNF-α  tumor necrosis factor α  Trans-N-(p-coumaroyl)tyramine (PubChem CID: 5372945)  Trans-N-feruloyltyramine (PubChem CID: 5280537)  Trans-N-caffeoyltyramine (PubChem CID: 9994897)  Dihydro-N-caffeoyltyramine (PubChem CID: 16119668)  CHEMBL2337120 (PubChem CID: 71524307)  CHEMBL2337119 (PubChem CID: 71524308)  CHEMBL2337118 (PubChem CID: 71524309)  CHEMBL2337115 (PubChem CID: 71719510)  CHEMBL2337117 (PubChem CID: 71524310)  Lycium chinense Miller  Lycii Radicis Cortex  NF-κB  PPARγ  Phenolic amides  Fatty acids  
SDS-PAGE-free protocol for comprehensive identification of cytochrome P450 enzymes and uridine diphosphoglucuronosyl transferases in human liver microsomes 期刊论文
proteomics, 2012, 卷号: 12, 期号: 23-24, 页码: 3464-3469
作者:  Sun, Liangliang;  Zhang, Yanyan;  Tao, Dingyin;  Zhu, Guijie;  Zhao, Qun
收藏  |  浏览/下载:84/0  |  提交时间:2015/11/13
Identification Keratin 1 as a cDDP-resistant protein in nasopharyngeal carcinoma cell lines 期刊论文
Journal of Proteomics, 2012, 卷号: 75, 期号: 8, 页码: 2352-2360
作者:  Tang, Sanyuan;  Huang, Weiguo;  Zhong, Meizuo*;  Yin, Leilan;  Jiang, Hao
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/03
KRT1  NPC  cDDP  MDR  ESI-Q-TOF-MS  2-DE  
Identification Keratin 1 as a cDDP-resistant protein in nasopharyngeal carcinoma cell lines 期刊论文
Journal of Proteomics, 2012, 卷号: 75, 期号: 8, 页码: 2352-2360
作者:  Tang, Sanyuan;  Huang, Weiguo;  Zhong, Meizuo*;  Yin, Leilan;  Jiang, Hao
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/27
KRT1  NPC  cDDP  MDR  ESI-Q-TOF-MS  2-DE  
Ultra-performance LC-photodiode array-el-ESI-MS/MS screening method for the detection of radical-scavenging natural antioxidants from Radix et Rhizoma Rhei 期刊论文
Journal of Separation Science, 2011, 卷号: 34, 页码: 268-277
作者:  Shi YP(师彦平);  Shi YP(师彦平)
收藏  |  浏览/下载:20/0  |  提交时间:2012/10/18
iTRAQ-2DLC-ESI-MS/MS Based Identification of a New Set of Immunohistochemical Biomarkers for Classification of Dysplastic Nodules and Small Hepatocellular Carcinoma 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2011, 卷号: 10, 期号: 8
作者:  Jin, Guang-Zhi;  Li, Yan;  Cong, Wen-Ming;  Yu, Hua;  Dong, Hui
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/19


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