CORC

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CORC

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Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens
收藏  |  浏览/下载：74/0  |  提交时间：2021/08/17
Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:  Zhou, Yan;  Du, Dao-Hai;  Wang, Jia;  Cai, Xiao-Qing;  Deng, Alicia X.
收藏  |  浏览/下载：102/0  |  提交时间：2020/07/01
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63
作者:  Zhu, Kongkai;  Du, Daohai;  Yang, Rui;  Tao, Hongrui;  Zhang, Hua
收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595
作者:  Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-fen;  Sun, Yi-ming;  Ding, Jian
收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01
C10ORF12 modulates PRC2 histone methyltransferase activity and H3K27me3 levels 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 11, 页码: 1457-1465
作者:  Shi, Yi;  Ma, Hong-lei;  Zhuang, You-wen;  Wang, Xiao-xi;  Jiang, Yi
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01
LncRNA SNHG17 promotes gastric cancer progression by epigenetically silencing of p15 and p57 期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: 234, 期号: 4, 页码: 5163-5174
作者:  Zhang, Guohua[1];  Xu, Ying[2];  Wang, Sijia[3];  Gong, Zhigang[4];  Zou, Chen[5]
收藏  |  浏览/下载：18/0  |  提交时间：2019/12/24
c10orf12modulatesprc2histonemethyltransferaseactivityandh3k27me3levels 期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 11, 页码: 1457
作者:  Shi Yi;  Ma Honglei;  Zhuang Youwen;  Wang Xiaoxi;  Jiang Yi
收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01
Development of a high-throughput fluorescence polarization assay for the discovery of EZH2-EED interaction inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 302-310
作者:  Zhu, Mao-rong;  Du, Dao-hai;  Hu, Jun-chi;  Li, Lian-chun;  Liu, Jing-qiu
收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08
Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function 期刊论文
MOLECULAR CELL, 2018, 卷号: Vol.69 No.2, 页码: 279
作者:  Wan, LX
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/26
Long noncoding RNA SYISL regulates myogenesis by interacting with polycomb repressive complex 2 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: Vol.115 No.42, 页码: E9802-E9811
作者:  Jin, Jian Jun;  Lv, Wei;  Xia, Pan;  Xu, Zai Yan;  Zheng, An Dai
收藏  |  浏览/下载：9/0  |  提交时间：2019/12/26

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