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上海药物研究所 [33]
大连化学物理研究所 [17]
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Time- and dose-dependent detoxification and reproductive endocrine disruption induced by tetrabromobisphenol A (TBBPA) in mussel Mytilus galloprovincialis
期刊论文
MARINE ENVIRONMENTAL RESEARCH, 2023, 卷号: 183, 页码: 10
作者:
Wang, Shuang
;
Sun, Zuodeng
;
Ren, Chuanbo
;
Li, Fei
;
Xu, Yingjiang
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/08/17
Tetrabromobisphenol A
Detoxification
Reproductive endocrine disruption
Sulfation
Mytilus galloprovincialis
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
UPLC-ESI-Q-TOF/MS Based Metabolic Profiling of Protosappanin B in Rat Plasma, Bile, Feces, Urine and Intestinal Bacteria Samples
期刊论文
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 6, 页码: 491-499
作者:
Chen, Wei-Ying
;
Liang, Guang-Yan
;
Zheng, Zuo-Liang
;
Wu, Yun-Shan
;
Xu, Fang-Fang
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/11/04
Protosappanin B
Metabolic pathways
UPLC-TOF-MS
MS
Plasma
Bile
Feces
Urine
Intestinal bacteria sample
Metabolic Profiling of Nuciferine in Vivo and in Vitro
期刊论文
Journal of Agricultural and Food Chemistry, 2020, 卷号: 68, 期号: 48, 页码: 14135-14147
作者:
Gao, Hua
;
Zhang, Lei
;
Zhu, An
;
Liu, Xiaoyan
;
Wang, Tianxia
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  |  
浏览/下载:6/0
  |  
提交时间:2022/02/17
Biomolecules
Enzymes
Mammals
Mass spectrometry
Metabolites
Broad spectrum
Drug formulations
High resolution mass spectrometry
Metabolic characteristics
Metabolic profiling
Molecular docking
Nelumbo nucifera
Recombinant enzymes
A phase II randomized trial of sodium oligomannate in Alzheimer's dementia
期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2020, 卷号: 12, 期号: 1, 页码: 10
作者:
Wang, Tao
;
Kuang, Weihong
;
Chen, Wei
;
Xu, Wenwei
;
Zhang, Liming
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2020/12/21
Sodium oligomannate
Efficacy
Safety
Alzheimer's disease
Clinical trial
A phase II randomized trial of sodium oligomannate in Alzheimer’s dementia
期刊论文
Alzheimer's Research & Therapy, 2020, 卷号: 12, 期号: 1
作者:
Wang,Tao
;
Kuang,Weihong
;
Chen,Wei
;
Xu,Wenwei
;
Zhang,Liming
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2020/12/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
Exploring the protective effects of Danqi Tongmai tablet on acute myocardial ischemia rats by comprehensive metabolomics profiling
期刊论文
PHYTOMEDICINE, 2020, 卷号: 74, 页码: 9
作者:
Li Zhenwei
;
Hou Jinjun
;
Deng Yanping
;
Zhi Haijuan
;
Wu Wenyong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/12/24
Danqi Tongmai tablet
Acute myocardial ischemia
Metabolomics
Lipidomics
Network pharmacology
Tissue-specific bioaccumulation, metabolism and excretion of tris (2-ethylhexyl) phosphate (TEHP) in rare minnow (Gobiocyprisrarus)
期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 261, 页码: 1-9
作者:
Hou, Rui
;
Xu, Yiping
;
Rao, Kaifeng
;
Feng, Chenglian
;
Wang, Zijian
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/09/15
Tris (2-ethylhexyl) phosphate (TEHP)
Bioaccumulation
Toxicokinetic
Metabolite parent concentration factor
In vivo metabolism
Biotransformation of 6:2 fluorotelomer alcohol by the whole soybean (Glycine max L. Merrill) seedlings
期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 257, 页码: 1-11
作者:
Zhang, Hongna
;
Wen, Bei
;
Huang, Honglin
;
Wang, Sen
;
Cai, Zongwei
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/09/14
6:2 Fluorotelomer alcohol
Perfluorocarboxylic acid
Biotransformation
GSH-Conjugated metabolite
Soybean
A comprehensive study of pomegranate flowers polyphenols and metabolites in rat biological samples by high-performance liquid chromatography quadrupole time-of-flight mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2019, 卷号: 1604, 页码: 13
作者:
Yisimayili, Zainaipuguli
;
Abdulla, Rahima
;
Tian, Qiang
;
Wang, Yangyang
;
Chen, Mingcang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Punica granatum L. flowers
Polyphenols
Ellagitannin
Metabolism
HPLC-Q-TOF-MS2
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