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湖南中医药大学 [2]
兰州大学 [1]
金属研究所 [1]
化学研究所 [1]
复旦大学上海医学院 [1]
中国医学科学院 北京... [1]
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期刊论文 [7]
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2019 [2]
2018 [1]
2017 [1]
2011 [1]
2008 [2]
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IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation
期刊论文
2019, 卷号: 212, 页码: 36-53
作者:
Ai Q D
;
Chen Chen
;
Chu Shifeng
;
Zhang Zhao
;
Luo Yun
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain
BCA = bicinchoninic acid
BSA = bovine serum albumin
CCA = common carotid artery
CCR4 = C-C chemokine receptor type 4
CKLF1 = chemokine-like factor 1
CO-IP = coimmunoprecipitation
ECA = external carotid artery
ELISA = enzyme-linked immunosorbent assay
FDA = Food and Drug Administration
I/R = ischemic/reperfusion
ICA = internal carotid artery
IL-18 = interleukin 18
IL-1β = interleukin 1β
LDH = lactate dehydrogenase
NLRP3 = NOD-like receptor protein 3
PBS = phosphate-buffered saline
SD = standard deviation
TNF-α = tumor necrosis factor α
TTC = 2
3
5-triphenyltetrazolium-chloride
WT = wild-type
pMCAO = permanent middle cerebral artery occlusion
pro-Caspase-1 = precursor Caspase-1
qPCR = quantitative real-time PCR
tMCAO = transient middle cerebral artery occlusion
tPA = tissue plasminogen activator
NK cells in cerebral ischemia
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, 卷号: 109, 页码: 547-554
作者:
Chen, Chen
;
Ai, Qi-Di
;
Chu, Shi-Feng
;
Zhang, Zhao
;
Chen, Nai-Hong*
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  |  
浏览/下载:36/0
  |  
提交时间:2019/12/27
tPA
tissue plasminogen activator
IS
ischemic stroke
BBB
blood-brain barrier
IFN-γ
interferon-γ
pMCAO
permanent middle cerebral artery occlusion
tMCAO
transient middle cerebral artery occlusion
CX3CR1
CX3CL1 receptor
CNS
central nervous system
AchE
acetylcholine esterase
CFSE
arboxyfluorescein diacetate succinimidyl ester
HI
hypoxic ischemia
MCAO IP-10
interferon-inducible protein-10
IL
interleukin
GFAP
glial fibrillary acidic protein
tg
transgenic
WT
wild-type
APC
antigen presenting cell
SAI
stroke-associated infection
STAT3
signal transducer and activator of transcription-3
HPA
hypothalamic-pituitary-adrenal
cSVD
cerebral small vessel disease
SHR
spontaneously hypertensive rat
CSF
cerebrospinal fluid
aSAH
aneurysmal subarachnoid hemorrhage
DCI
delayed cerebral ischemia
MRI
magnetic resonance imaging
CT
computed tomography
EVs
extracellular vesicles
MSC
mesenchymal stem cell
MNCs
bone marrow-derived mononuclear cells
CpG-ODN
cytosine-guanine oligodideoxynucleotide
TLR9
toll-like receptor 9
TNF
tumor necrosis factor
NK cells
Cerebral ischemia
Inflammation
Immunodpression
Infection
Chemokines play complex roles in cerebral ischemia
期刊论文
Neurochemistry International, 2018, 卷号: 112, 页码: 146-158
作者:
Chen, Chen
;
Chu, Shi-Feng
;
Liu, Dan-Dan
;
Zhang, Zhao
;
Kong, Ling-Lei
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/12/27
Chemokine
Cerebral ischemia
Ischemic stroke
IS
ischemic stroke
NSCs
neural stem cell
NPCs
neural progenitor cells
BMSCs
bone marrow stromal cells
ELR
glutamic acid-leucine-arginine
MCP
monocytes chemoattractant protein
MCAo
middle cerebral artery occlusion
tMCAo
transient MCAo
CNS
central nervous system
MIP
macrophage inflammatory protein
BBB
blood brain barrier
HI
hypoxia ischemia
CSF
cerebrospinal fluid
CI
cerebral infarction
WT
wildtype
pMCAo
permanent MCAo
ET
endothelin
I/R
ischemia/reperfusion
SCID
Severe Combined Immunodeficiency
ENA-78
epithelial neutrophil-activating peptide-78
IL-8
interleukin 8
PMNL
polymorphonuclear leukocyte
MSCs
mesenchymal stem cells
VEGF
vascular endothelial growth factor
CINC
cytokine-induced neutrophil chemoattractant
IP-10
interferon-gamma inducible protein-10
NK
natural killer
SDF-1
stromal cell-derived factor-1
EPCs
endothelial progenitor cells
HSCs
hematopoietic stem cells
HUVECs
human umbilical vein endothelial cells
TIA
transient ischemic attack
OGD
oxygen glucose deprivation
GPCs
glial precursor cells
CMKLR1
chemerin-like receptor-1
AIS
acute ischemic stroke
CKLF1
chemokine-like factor 1
CBP
chemokine-binding protein
Effects of Dl-3-n-butylphthalide on Cerebral Ischemia Infarction in Rat Model by Mass Spectrometry Imaging
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 卷号: 18, 期号: 11
作者:
Liu, Run-Zhe
;
Fan, Chao-Xin
;
Zhang, Zhi-Lin
;
Zhao, Xin
;
Sun, Yi
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/04/09
Dl-3-n-butylphthalide
Permanent Middle Cerebral Artery Occlusion (Pmcao)
Matrix-assisted Laser Desorption Time Of Flight Ionization Mass Spectrometry Imaging (maldi-tOf-ms Imaging)
Metabolites
Bilobalide inhibits the expression of aquaporin 1,4 and glial fibrillary acidic protein in rat brain tissue after permanent focal cerebral ischemia
期刊论文
NEURAL REGENERATION RESEARCH, 2011, 卷号: 6, 期号: 27, 页码: 2105-2111
作者:
Qin Haiming
;
Song Fulin
;
Han Hongguang
;
Qu Hong
;
Zhai Xingwen
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2021/02/26
ARTERY OCCLUSION
WATER CHANNELS
EXTRACT EGB-761
EDEMA
NEUROPROTECTION
PERMEABILITY
ASTROCYTES
PROTECTION
MEMBRANE
INJURY
bilobalide
aquaporin
brain edema
permanent middle cerebral artery occlusion
glial fibrillary acidic protein
neural regeneration
用阿托伐他汀保护急性脑缺血大鼠脑的研究
期刊论文
第四军医大学学报, 2008, 期号: 7, 页码: 619-622
作者:
陈凤
;
王江昆
;
王德贵
;
侯一平
;
宋焱峰
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2016/09/09
阿托伐他汀
脑缺血
药物疗法
红四氮唑
CD34
微血管计数
延迟亚低温治疗对大鼠永久性大脑中动脉阻塞后凋亡相关蛋白表达的影响
期刊论文
中风与神经疾病杂志, 2008, 卷号: 25, 期号: 1
作者:
吕佳宁(1)
;
韩锁成(2)
;
郭景春(3)
;
范薇(1)
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
pMCAO
凋亡
亚低温
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