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科研机构
上海药物研究所 [17]
厦门大学 [16]
北京大学 [10]
上海生物化学与细胞... [10]
复旦大学上海医学院 [9]
清华大学 [6]
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期刊论文 [131]
学位论文 [2]
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浏览/检索结果:
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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGF beta signaling
期刊论文
ONCOGENE, 2021, 页码: 10
作者:
Kong, Ya
;
Zhang, Yutian
;
Wang, Hanlin
;
Kan, Weijuan
;
Guo, Haoran
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2022/01/04
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP)
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:
Wang, Xiaoqing
;
Li, Fei
;
Liu, Jialin
;
Ji, Chenglong
;
Wu, Huifeng
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/06/21
Triphenyl phosphate (TPP)
Multi-omit approach
Hepatotoxicity
Progress on treatment of MET signaling pathway in non-small cell lung cancer
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 2020
作者:
Yu, Xiaoqing
;
Yu, Sizhe
;
Fan, Yun
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/11/26
MET
Dysregulation
Overexpression
Amplification
Non-small cell lung cancer
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway
期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:
Xu, Qi
;
Wu, Ning
;
Li, Xiangqian
;
Guo, Chuanlong
;
Li, Chao
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/03/20
VPAC1 couples with TRPV4 channel to promote calcium-dependent gastric cancer progression via a novel autocrine mechanism
期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 20, 页码: 3946-3961
作者:
Tang, Bo
;
Wu, Jilin
;
Zhu, Michael X.
;
Sun, Xuemei
;
Liu, Jingjing
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
2-ethoxystypandrone, a novel small-molecule stat3 signaling inhibitor from polygonum cuspidatum, inhibits cell growth and induces apoptosis of hcc cells and hcc cancer stem cells
期刊论文
Bmc complementary and alternative medicine, 2019, 卷号: 19, 页码: 13
作者:
Li, Wuguo
;
Zhang, Qing
;
Chen, Kaotan
;
Sima, Zhenhua
;
Liu, Jingli
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2019/05/08
Polygonum cuspidatum
2-ethoxystypandrone
Hepatocellular carcinoma
Cancer stem cells
Stat3 signaling pathway
Cancer stemness inhibitor
2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells
期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019, 卷号: 19, 页码: 13
作者:
Li, Wuguo
;
Zhang, Qing
;
Chen, Kaotan
;
Sima, Zhenhua
;
Liu, Jingli
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
Polygonum cuspidatum
2-Ethoxystypandrone
Hepatocellular carcinoma
Cancer stem cells
STAT3 signaling pathway
Cancer stemness inhibitor
Transcriptional repression of IKK beta by p53 in arsenite-induced GADD45 alpha accumulation and apoptosis
期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 5, 页码: 731-746
作者:
Hu, Yongliang
;
Jin, Rui
;
Gao, Ming
;
Xu, Huan
;
Zou, Shuxian
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/10/21
Targeting surface nucleolin induces autophagy-dependent cell death in pancreatic cancer via AMPK activation
期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 11
作者:
Xu, Cheng
;
Wang, Yunfei
;
Tu, Qiu
;
Zhang, Zhiye
;
Chen, Mengrou
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/04
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