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浏览/检索结果: 共11条，第1-10条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 肿瘤、肠器官芯片的构建及壳寡糖活性评价 学位论文 : 中国科学院大学, 2020 作者:  荆柏林 收藏  |  浏览/下载：40/0  |  提交时间：2021/09/07 壳寡糖,器官芯片,肿瘤转移模型,蠕动大肠模型   Metabolism, pharmacokinetics, and hepatic disposition of xanthones and saponins on Zhimu treatments for exploratively interpreting the discrepancy between the herbal safety and timosaponin A3-induced hepatotoxicity 期刊论文 Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1923-1934 作者:  Xie, Yang;  Zhou, Xu;  Pei, Hu;  Chen, Ming-Cang;  Sun, Zhao-Lin 收藏  |  浏览/下载：93/0  |  提交时间：2019/01/08 Simultaneous determination of eight bioactive compounds by LC-MS/MS and its application to the pharmacokinetics, liver first-pass effect, liver and brain distribution of orally administrated Gouteng-Baitouweng (GB) in rats 期刊论文 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2018, 卷号: 1084, 页码: 122-131 作者:  Tian, Xiaoting;  Xu, Zhou;  Chen, Mingcang;  Hu, Pei;  Liu, Fang 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 Gouteng-Baitouweng  LC-MS/MS  Pharmacokinetics  Liver  Brain  liver first-pass effect   A sensitive HPLC-MS/MS method for the simultaneous determination of anemoside B4, anemoside A3 and 23-hydroxybetulinic acid: Application to the pharmacokinetics and liver distribution of Pulsatilla chinensis saponins 期刊论文 BIOMEDICAL CHROMATOGRAPHY, 2018, 卷号: 32, 期号: 3 作者:  Guo, Xiaozhen;  Xie, Yang;  Lian, Shan;  Li, Zhixiong;  Gao, Yu 收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 23-hydroxybetulinic acid  HPLC-MS  MS  liver distribution  pharmacokinetics  Pulsatilla chinensis saponins   Green Algae as Carriers Enhance the Bioavailability of C-14-Labeled Few-Layer Graphene to Freshwater Snails 期刊论文 ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2018, 卷号: 52, 期号: 3, 页码: 1591-1601 作者:  Su, Yu;  Tong, Xin;  Huang, Chi;  Chen, Jiani;  Liu, Sijin 收藏  |  浏览/下载：23/0  |  提交时间：2019/06/20 Absorption, liver first-pass effect, pharmacokinetics and tissue distribution of calycosin-7-O-beta-D-glucopyranoside (C7G) and its major active metabolite, calycosin, following oral administration of C7G in rats by LC-MS/MS 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 卷号: 148, 页码: 350-354 作者:  Tian, Xiaoting;  Chen, Shuoji;  Zhang, Yuanyuan;  Chen, Luying;  Guo, Xiaozhen 收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 Calycosin-7-O-beta-D-glucopyranoside  Calycosin  Pharmacokinetics  Liver first-pass effect  Tissue distribution   Absorption, liver first-pass effect, pharmacokinetics and tissue distribution of calycosin-7-O-ß-d-glucopyranoside (C7G) and its major active metabolite, calycosin, following oral administration of C7G in rats by LC-MS/MS. 期刊论文 Journal Of Pharmaceutical And Biomedical Analysis, 2018, 卷号: Vol.148, 页码: 350-354 作者:  Tian X;  Chen S;  Zhang Y;  Chen L;  Guo X 收藏  |  浏览/下载：9/0  |  提交时间：2019/02/25 Calycosin  Calycosin-7-O-ß-d-glucopyranoside  Liver first-pass effect  Pharmacokinetics  Tissue distribution   metabolismpharmacokineticsandhepaticdispositionofxanthonesandsaponinsonzhimutreatmentsforexplorativelyinterpretingthediscrepancybetweentheherbalsafetyandtimosaponina3inducedhepatotoxicity 期刊论文 actapharmacologicasinica, 2018, 卷号: 39, 期号: 12, 页码: 1923 作者:  Xie Yang;  Zhou Xu;  Pei Hu;  Chen Mingcang;  Sun Zhaolin 收藏  |  浏览/下载：5/0  |  提交时间：2020/07/01 B-II  LIVER-INJURY  IN-VITRO  ANEMARRHENA-ASPHODELOIDES  OXIDATIVE STRESS  RAT PLASMA  A-III  MANGIFERIN  NORATHYRIOL  EXTRACT  Zhimu  timosaponin A3  mangiferin  pharmacokinetics  metabolism  hepatotoxicity  antioxidant   Pharmacokinetics of mangiferin and its metabolite-Norathyriol, Part 1: Systemic evaluation of hepatic first-pass effect in vitro and in vivo 期刊论文 BIOFACTORS, 2016, 卷号: 42, 期号: 5, 页码: 533-544 作者:  Tian, Xiaoting;  Gao, Yu;  Xu, Zhou;  Lian, Shan;  Ma, Yuanjie 收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 mangiferin  norathyriol  pharmacokinetics  metabolism  liver   An Examination of the Potential Effect of Lipids on the First-Pass Metabolism of the Lipophilic Drug Anethol Trithione 期刊论文 JOURNAL OF PHARMACEUTICAL SCIENCES, 2011, 卷号: 100, 期号: 11, 页码: 5048-5058 作者:  Yu, Hong-Zhen;  Han, Si-Fei;  Li, Ping;  Zhu, Chun-Liu;  Zhang, Xin-Xin 收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 anethol trithione  medium chain triglycerides  first-pass metabolism  hepatic metabolism  nonlinear pharmacokinetics  dose proportionality  drug metabolizing enzymes  inhibition  formulation  lipids