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Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:  Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li
收藏  |  浏览/下载:114/0  |  提交时间:2021/05/24
Uncovering kappa-opioid receptor agonist-induced PAK1/2 phosphorylation by quantitative phosphoproteomics 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 516, 期号: 1, 页码: 320-326
作者:  Wu, Jianhong;  Jiang, Qinghui;  Zhu, Hongwen;  Zhou, Yanting;  Lu, Dayun
收藏  |  浏览/下载:42/0  |  提交时间:2020/07/01
How Does Agonist and Antagonist Binding Lead to Different Conformational Ensemble Equilibria of the kappa-Opioid Receptor: Insight from Long-Time Gaussian Accelerated Molecular Dynamics Simulation 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 3, 页码: 1575-1584
作者:  An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Zhou, Shuangyan;  Shi, Danfeng
收藏  |  浏览/下载:57/0  |  提交时间:2019/11/10
Pharmacological Characterization of Dezocine, a Potent Analgesic Acting as a kappa Partial Agonist and mu Partial Agonist 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:  Wang, Yu-Hua;  Chai, Jing-Rui;  Xu, Xue-Jun;  Ye, Ru-Feng;  Zan, Gui-Ying
收藏  |  浏览/下载:89/0  |  提交时间:2019/01/08
7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14, 页码: 4254-4263
作者:  Sun, Hui-jiao;  Wang, Yu-hua;  Yuan, Cong-min;  Kong, Ling-hui;  Xu, Xue-jun
收藏  |  浏览/下载:80/0  |  提交时间:2019/01/08
Computational insights into the subtype selectivity and "message-address-efficacy" mechanisms of opioid receptors through JDTic binding and unbinding 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 3, 页码: 482-491
作者:  Cheng, Jian-xin;  Cheng, Tao;  Li, Wei-hua;  Liu, Gui-xia;  Zhu, Wei-liang
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Genetic association analyses and meta-analysis of Dynorphin-Kappa Opioid system potential functional variants with heroin dependence. 期刊论文
Neuroscience letters, 2018, 卷号: 685, 页码: 75-82
作者:  Yuanyuan Ji;  Rui Su;  Hua Tang;  Jingjing Cui;  Cuola Deji
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/26
Immunohistochemical identification of dynorphin A and Kappa opioid receptor-1 in the digestive system of scallop Chlamys farreri 期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2018, 卷号: 36, 期号: 6, 页码: 2288-2296
作者:  Sun Hushan;  Wang Yiyan;  Liu Xiaoli;  Liu Dcmgwu
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/11
GPCR Activation and Endocytosis Induced by a 2D Material Agonist 期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2017, 卷号: 9, 期号: 17, 页码: 14709-14715
作者:  Dou, Wei-Tao;  Kong, Ya;  He, Xiao-Peng;  Chen, Guo-Rong;  Zang, Yi
收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08
Nerve injury-induced epigenetic silencing of opioid receptors controlled by DNMT3a in primary afferent neurons 期刊论文
PAIN, 2017, 卷号: 158, 期号: 6
作者:  Sun, Linlin;  Zhao, Jian-Yuan;  Gu, Xiyao;  Liang, Lingli;  Wu, Shaogen
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/05


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