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Effect of Hydrophobic Chain Length in Amphiphilic Chitosan Conjugates on Intracellular Drug Delivery and Smart Drug Release of Redox-Responsive Micelle
期刊论文
MARINE DRUGS, 2024, 卷号: 22, 期号: 1, 页码: 18
作者:
Yuan, Yuting
;
Tan, Wenqiang
;
Mi, Yingqi
;
Wang, Linqing
;
Qi, Zhen
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
different hydrophobic chain length
low molecular weight chitosan
trigger-release
Redox-sensitive self-assembled micelles based on low molecular weight chitosan-lipoic acid conjugates for the delivery of doxorubicin: Effect of substitution degree of lipoic acid
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 247, 页码: 14
作者:
Yuan, Yuting
;
Wang, Zhenhua
;
Su, Shengjia
;
Mi, Yingqi
;
Li, Qing
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/01/26
Amphiphilic polymer
Doxorubicin
Drug delivery
Release-trigger release
Self-assembled micelle
The reversal of anti-HER2 resistance in advanced HER2-positive breast cancer using apatinib: two cases reports and literature review
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2022
作者:
He, Libin
;
Shen, Xiabo
;
Liu, Yiyuan
;
Gao, Lu
;
Wu, Jiayi
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  |  
浏览/下载:19/0
  |  
提交时间:2022/12/23
Advanced human epidermal growth factor receptor 2-positive breast cancer (advanced HER2-positive breast cancer)
apatinib
case report
Tisotumab vedotin for the treatment of cervical carcinoma
期刊论文
DRUGS OF TODAY, 2022, 卷号: 58, 期号: 5, 页码: 213-222
作者:
Song, Xin
;
Li, Ruyi
;
Wang, Hongwei
;
Song, Peng
;
Guo, Wenjing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/06/21
Tisotumab vedotin
Antibody-drug conjugates
Cervical cancer
Tissue factor
Monomethyl auristatin E
Targeted antitumor drugs
Cancer immunotherapy
Gynecological cancers
Characterization of the metabolites of tirabrutinib generated from rat, dog and human liver microsomes using ultra-high-performance liquid chromatography combined with high-resolution mass spectrometry
期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2022, 卷号: 36
作者:
Zhang, Hongjian
;
Hu, Zhen
;
Zhang, Huiping
;
Sun, Xiyan
;
Yang, Jianming
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  |  
浏览/下载:40/0
  |  
提交时间:2022/03/28
Engineering Enzyme-Cleavable Oligonucleotides by Automated Solid-Phase Incorporation of Cathepsin B Sensitive Dipeptide Linkers
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022
作者:
Jin, Cheng
;
Ei-Sagheer, Afaf H.
;
Li, Siqi
;
Vallis, Katherine A.
;
Tan, Weihong
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  |  
浏览/下载:84/0
  |  
提交时间:2022/03/21
Cathepsin B
DNA Breakage
Dipeptide Linker
Oligonucleotide-Drug Conjugates
Solid-Phase Synthesis
Lipophilic Conjugates of Drugs: A Tool to Improve Drug Pharmacokinetic and Therapeutic Profiles
期刊论文
PHARMACEUTICAL RESEARCH, 2021, 页码: 22
作者:
Han, Sifei
;
Mei, Lianghe
;
Quach, Tim
;
Porter, Chris
;
Trevaskis, Natalie
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  |  
浏览/下载:36/0
  |  
提交时间:2021/11/04
conjugate
lipid
lymphatic
pharmacokinetics
prodrug
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
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  |  
浏览/下载:47/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
Design, synthesis, and antibacterial evaluation of vancomycin-LPS binding peptide conjugates
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 45, 页码: 8
作者:
Shi, Weiwei
;
Chen, Feifei
;
Zou, Xiangman
;
Jiao, Shang
;
Wang, Siqi
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/08/17
Vancomycin analogues
LPS binding peptides
Vancomycin-Peptide Conjugates
Antibacterial activity
Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Meng, Jian
;
Zhang, Hua
;
Bao, Jing-jing
;
Chen, Zhen-dong
;
Liu, Xiao-yun
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  |  
浏览/下载:69/0
  |  
提交时间:2021/06/11
metabolism
mass balance
distribution
covalent binding
furmonertinib
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